دورية أكاديمية
أعرض في EDS

Predictive accuracy of genetic variants for eye color in a Kazakh population using the IrisPlex system.

التفاصيل البيبلوغرافية
العنوان: Predictive accuracy of genetic variants for eye color in a Kazakh population using the IrisPlex system.
المؤلفون: Bukayev A; National Center for Biotechnology, Astana, 010000, Kazakhstan., Gorin I; Research Centre for Medical Genetics, Moscow, 115522, Russia., Aidarov B; National Center for Biotechnology, Astana, 010000, Kazakhstan., Darmenov A; Karaganda Academy of the Ministry of Internal Affairs of the Republic of Kazakhstan named after Barimbek Beisenov, Karaganda, 100000, Kazakhstan., Balanovska E; Research Centre for Medical Genetics, Moscow, 115522, Russia., Zhabagin M; National Center for Biotechnology, Astana, 010000, Kazakhstan. zhabagin@biocenter.kz.
المصدر: BMC research notes [BMC Res Notes] 2024 Jul 05; Vol. 17 (1), pp. 187. Date of Electronic Publication: 2024 Jul 05.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Biomed Central Country of Publication: England NLM ID: 101462768 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-0500 (Electronic) Linking ISSN: 17560500 NLM ISO Abbreviation: BMC Res Notes Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Biomed Central, 2008.
مواضيع طبية MeSH: Eye Color*/genetics, Humans ; Kazakhstan ; Genetic Variation/genetics ; Phenotype ; Genotype ; Genetics, Population/methods ; Asian People/genetics
مستخلص: Objective: This study assesses the accuracy of the IrisPlex system, a genetic eye color prediction tool for forensic analysis, in the Kazakh population. The study compares previously published genotypes of 515 Kazakh individuals from varied geographical and ethnohistorical contexts with phenotypic data on their eye color, introduced for the first time in this research.
Results: The IrisPlex panel's effectiveness in predicting eye color in the Kazakh population was validated. It exhibited slightly lower accuracy than in Western European populations but was higher than in Siberian populations. The sensitivity was notably high for brown-eyed individuals (0.99), but further research is needed for blue and intermediate eye colors. This study establishes IrisPlex as a useful predictive tool in the Kazakh population and provides a basis for future investigations into the genetic basis of phenotypic variations in this diverse population.
(© 2024. The Author(s).)
References: Forensic Sci Int Genet. 2023 Jul;65:102870. (PMID: 37084623)
Croat Med J. 2013 Aug;54(4):381-6. (PMID: 23986280)
Hum Genet. 2011 Apr;129(4):443-54. (PMID: 21197618)
Am J Hum Genet. 2008 Feb;82(2):424-31. (PMID: 18252222)
Mol Biol (Mosk). 2022 Sep-Oct;56(5):860-880. (PMID: 36165022)
Am J Hum Genet. 2007 Dec;81(6):1119-32. (PMID: 17999355)
Sci Adv. 2021 Mar 10;7(11):. (PMID: 33692100)
Pigment Cell Melanoma Res. 2016 Mar;29(2):141-62. (PMID: 26547379)
Forensic Sci Int Genet. 2014 Jul;11:1-6. (PMID: 24631691)
Bioinformatics. 2012 Oct 1;28(19):2537-9. (PMID: 22820204)
Biomedicines. 2023 Apr 20;11(4):. (PMID: 37189847)
Genome Res. 2012 Mar;22(3):446-55. (PMID: 22234890)
Forensic Sci Int Genet. 2013 Jan;7(1):28-40. (PMID: 22709892)
J Invest Dermatol. 2009 Sep;129(9):2250-7. (PMID: 19340012)
Croat Med J. 2013 Jun;54(3):248-56. (PMID: 23771755)
Hum Genet. 2015 Aug;134(8):823-35. (PMID: 25963972)
Sci Rep. 2017 Feb 27;7:43359. (PMID: 28240252)
PLoS Genet. 2010 May 06;6(5):e1000934. (PMID: 20463881)
Am J Hum Genet. 2007 Feb;80(2):241-52. (PMID: 17236130)
PLoS One. 2012;7(10):e48294. (PMID: 23118974)
Eur J Hum Genet. 2013 Nov;21(11):1320-3. (PMID: 23486544)
Genes (Basel). 2023 Aug 10;14(8):. (PMID: 37628655)
Forensic Sci Int Genet. 2019 Mar;39:109-118. (PMID: 30639910)
Forensic Sci Int Genet. 2014 Mar;9:111-7. (PMID: 24528589)
Am J Hum Genet. 2008 Feb;82(2):411-23. (PMID: 18252221)
Forensic Sci Int Genet. 2019 May;40:192-200. (PMID: 30884346)
Pigment Cell Res. 2002 Jun;15(3):217-24. (PMID: 12028586)
PLoS Genet. 2010 Jun 24;6(6):e1000993. (PMID: 20585627)
Methods Mol Biol. 2016;1420:213-31. (PMID: 27259743)
Forensic Sci Int Genet. 2013 Sep;7(5):508-15. (PMID: 23948321)
Forensic Sci Int Genet. 2011 Jun;5(3):170-80. (PMID: 20457092)
J Invest Dermatol. 2015 Jul;135(7):1735-1742. (PMID: 25705849)
Nature. 1985 Dec 12-18;318(6046):577-9. (PMID: 3840867)
Int J Legal Med. 2014 May;128(3):447-53. (PMID: 24395150)
Sci Rep. 2022 Jul 27;12(1):12803. (PMID: 35896692)
Science. 2019 Sep 6;365(6457):. (PMID: 31488661)
Genes (Basel). 2022 Nov 11;13(11):. (PMID: 36421769)
BMC Res Notes. 2024 Feb 18;17(1):51. (PMID: 38369539)
Forensic Sci Int Genet. 2012 May;6(3):330-40. (PMID: 21813346)
Int J Mol Sci. 2016 Jul 15;17(7):. (PMID: 27428965)
Nat Ecol Evol. 2019 Jun;3(6):966-976. (PMID: 31036896)
Nat Rev Genet. 2011 Mar;12(3):179-92. (PMID: 21331090)
PLoS Genet. 2008 May 16;4(5):e1000074. (PMID: 18483556)
معلومات مُعتمدة: AP09058276 Science Committee of the Ministry of Science and Higer Education of the Republic of Kazakhstan; AP09058276 Science Committee of the Ministry of Science and Higer Education of the Republic of Kazakhstan; AP09058276 Science Committee of the Ministry of Science and Higer Education of the Republic of Kazakhstan; AP09058276 Science Committee of the Ministry of Science and Higer Education of the Republic of Kazakhstan
فهرسة مساهمة: Keywords: Eye color; Forensic genetics, IrisPlex System; Kazakh population; Microarray; SNP Genotyping
تواريخ الأحداث: Date Created: 20240705 Date Completed: 20240706 Latest Revision: 20240708
رمز التحديث: 20240708
مُعرف محوري في PubMed: PMC11227171
DOI: 10.1186/s13104-024-06856-y
PMID: 38970104
قاعدة البيانات: MEDLINE
الوصف
تدمد:1756-0500
DOI:10.1186/s13104-024-06856-y