دورية أكاديمية
Chitosan/MgO NPs/CQDs bionanocomposite coating: Fabrication, characterization and determination of antimicrobial efficacy.
| العنوان: | Chitosan/MgO NPs/CQDs bionanocomposite coating: Fabrication, characterization and determination of antimicrobial efficacy. |
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| المؤلفون: | Basati M; Department of Materials Science and Engineering, Razi University, Kermanshah, Iran., Moghadam A; Department of Materials Science and Engineering, Razi University, Kermanshah, Iran. Electronic address: a.moghadam@razi.ac.ir., Khazaei BA; Department of Materials Science and Engineering, Razi University, Kermanshah, Iran., Hajkarim MC; Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. |
| المصدر: | International journal of biological macromolecules [Int J Biol Macromol] 2024 Sep; Vol. 276 (Pt 1), pp. 133693. Date of Electronic Publication: 2024 Jul 05. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Guildford, Eng., IPC Science and Technology Press. |
| مواضيع طبية MeSH: | Chitosan*/chemistry , Chitosan*/pharmacology , Nanocomposites*/chemistry , Magnesium Oxide*/chemistry , Magnesium Oxide*/pharmacology , Staphylococcus aureus*/drug effects , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Microbial Sensitivity Tests*, Quantum Dots/chemistry ; Coated Materials, Biocompatible/chemistry ; Coated Materials, Biocompatible/pharmacology |
| مستخلص: | The development of new polymer nanocomposites or antibacterial coatings is crucial in combating drug-resistant infections, particularly bacterial infections. In this study, a new chitosan polymer based nanocomposite reinforced with magnesium oxide nanopowders and carbon quantum dots was fabricated by sol-gel technique and coated on 316 L stainless steel. In order to gaining the optimal amount of components to achieve the maximum antibacterial properties, the effect of concentration of nanocomposite components on its antibacterial properties was investigated. Crystal structure, microstructure, elemental dispersion, size distribution, chemical composition and morphology of nanocomposite and coating were characterized with various analyses. The obtained results exhibited that the carbon quantum dot and magnesium oxide nanopowders were distributed uniformly and without agglomeration in the chitosan matrix and created a uniform coating. The antibacterial properties of the synthesized samples against Staphylococcus aureus bacteria (gram positive) were evaluated using disk diffusion and minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) antibacterial tests. The inhibition growth zone formed around the antibiotic and nanocomposite 25 mg/ml under dark and light was about 32 and 14, 11 mm, respectively. Also, MIC and MBC values for final nanocomposite were 62.5 and 125 μg/ml, respectively. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: The authors declare that no funds, grants, or other support were received during the preparation of this manuscript. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Antibacterial; Carbon quantum dots; Chitosan; Magnesium oxide; Nanocomposite coating; Sol-gel dipping process |
| المشرفين على المادة: | 9012-76-4 (Chitosan) 3A3U0GI71G (Magnesium Oxide) 0 (Anti-Bacterial Agents) 0 (Coated Materials, Biocompatible) |
| تواريخ الأحداث: | Date Created: 20240706 Date Completed: 20240823 Latest Revision: 20240823 |
| رمز التحديث: | 20240823 |
| DOI: | 10.1016/j.ijbiomac.2024.133693 |
| PMID: | 38971277 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-0003 |
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| DOI: | 10.1016/j.ijbiomac.2024.133693 |