دورية أكاديمية
"Intraosseous administration of tenecteplase for thrombolysis of an acute ischemic stroke".
| العنوان: | "Intraosseous administration of tenecteplase for thrombolysis of an acute ischemic stroke". |
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| المؤلفون: | Chung J; University of Illinois Hospital and Health Sciences System, United States; University of Illinois Chicago College of Pharmacy, United States. Electronic address: Jinjoo.chung@gmail.com., Bundy J; University of Illinois Hospital and Health Sciences System, United States., Khan S; University of Illinois Hospital and Health Sciences System, United States., Hunt A; University of Illinois Chicago College of Pharmacy, United States., Carroll S; University of Illinois Hospital and Health Sciences System, United States; University of Illinois Chicago College of Pharmacy, United States., Ali A; University of Illinois Hospital and Health Sciences System, United States., Shafi N; University of Illinois Hospital and Health Sciences System, United States., Tesoro E; University of Illinois Hospital and Health Sciences System, United States; University of Illinois Chicago College of Pharmacy, United States. |
| المصدر: | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2024 Jul 04; Vol. 33 (9), pp. 107850. Date of Electronic Publication: 2024 Jul 04. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Saunders Country of Publication: United States NLM ID: 9111633 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8511 (Electronic) Linking ISSN: 10523057 NLM ISO Abbreviation: J Stroke Cerebrovasc Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia, PA : Saunders Original Publication: New York, NY : Demos Publications, [1991- |
| مستخلص: | Intro: Current guidelines for acute ischemic stroke recommend timely administration of intravascular thrombolytic therapy to promote functional and neurologic outcomes. Tenecteplase is an emerging off-label therapy for this indication and being utilized by various institutions due to its simpler administration strategy. In emergent situations in which intravenous access cannot be obtained, intraosseous access is a viable option for medication administration. However, there has been minimal published cases to support the efficacy and safety of intraosseous administration of tenecteplase for acute ischemic stroke. Case: We describe the case of a 51-year-old woman who developed acute ischemic stroke within our institution. Due to difficulty achieving intravenous access and time-dependent efficacy of thrombolytic therapy, the decision was made to administer tenecteplase by the intraosseous route. Stroke symptoms improved within 48 hours following administration without complication. Conclusion: Intraosseous administration of tenecteplase may be considered for treatment of acute ischemic stroke if intravenous access is unattainable. Competing Interests: Declaration of competing interest None. (Copyright © 2024. Published by Elsevier Inc.) |
| فهرسة مساهمة: | Keywords: Intraosseous; Ischemic; Stroke; Tenecteplase; Thrombolytic |
| تواريخ الأحداث: | Date Created: 20240706 Latest Revision: 20240728 |
| رمز التحديث: | 20240729 |
| DOI: | 10.1016/j.jstrokecerebrovasdis.2024.107850 |
| PMID: | 38971481 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1532-8511 |
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| DOI: | 10.1016/j.jstrokecerebrovasdis.2024.107850 |