دورية أكاديمية
Medical Biomonitoring of Maternal and Fetal Exposure to Carbon Monoxide and its Modification by Demographic and Obstetric Characteristics.
| العنوان: | Medical Biomonitoring of Maternal and Fetal Exposure to Carbon Monoxide and its Modification by Demographic and Obstetric Characteristics. |
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| المؤلفون: | Mkpe A; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Chijioke AS; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Oloyede OA; Department of Obstetrics and Gynaecology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria., Iwo-Amah RS; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Kua PL; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Okagua EK; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Altraide BO; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Horsfall F; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Nonye-Enyidah EI; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Kwosah NJ; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Mba AG; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Ocheche US; PAMO University of Medical Sciences. Port Harcourt, Rivers State, Nigeria., Sapira-Ordu L; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., John DH; Rivers State University Teaching Hospital (RSUTH), Port Harcourt, Rivers State, Nigeria., Inimgba NM; PAMO University of Medical Sciences. Port Harcourt, Rivers State, Nigeria. |
| المصدر: | Nigerian medical journal : journal of the Nigeria Medical Association [Niger Med J] 2024 Feb 22; Vol. 64 (6), pp. 744-758. Date of Electronic Publication: 2024 Feb 22 (Print Publication: 2023). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nigerian Medical Association Country of Publication: Nigeria NLM ID: 0315137 Publication Model: eCollection Cited Medium: Print ISSN: 0300-1652 (Print) Linking ISSN: 03001652 NLM ISO Abbreviation: Niger Med J Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2021- : Abuja, Nigeria : Nigerian Medical Association Original Publication: Lagos : Literamed Publications (Nig.) Ltd. |
| مستخلص: | Background: There is a paucity of organized human biomonitoring, including that of carbon monoxide (CO) in the Niger Delta, Nigeria. The study aims to quantify the impact of maternal exposure to CO in the first trimester of pregnancy and its modification by maternal demographic and obstetric factors. Methodology: It was of cross-sectional design conducted at the Rivers State University Teaching Hospital (RSUTH) in Nigeria. Four hundred and ninety consecutive pregnant women in the first trimester were recruited from the antenatal clinic from January 2021 to January 2022. Demographic, social, and obstetric characteristics were recorded. Maternal exhaled CO concentration (ECOC) and maternal and fetal carboxyhaemoglobin concentrations (MCOHC and FCOHC) were measured with the aid of a smokelyzer. Data were analyzed, using SPSS version 25.0 software. Ethical approval was obtained from the RSUTH Ethics Committee. Results: The mean values of ECOC, MCOHC, and FCOHC were 3.25±2.51 ppm, 1.15±0.40%, and 0.93±0.72% respectively and the severity (mild, moderate, and severe) of the impact was inversely proportional to the number of women affected. There were statistically significant differences in the mean values of ECOC, MCOHC, and FCOHC in the following maternal characteristics: age, educational levels, BMI, gravidity, and parity. In the case of FCOHC, the measures of the differences were as follows: p:<0.019, <0.020, <0.0001, <0.0001, and <0.038 for age categories, educational levels, BMI, gravidity, and parity respectively. There were statistically significant positive correlations between the BMI and the mean values of ECOC, MCOHC, and FCOHC. Conclusion: The higher the severity of exposure to CO (mild, moderate, and severe), the lower the number of impacted pregnant women. There were statistically significant differences in the mean values of ECOC, MCOHC, and FCOHC in women of different ages, educational levels, BMI, gravidity, and parity categories. (Copyright © 2023 Nigerian Medical Association.) |
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| فهرسة مساهمة: | Keywords: Carbon Monoxide; Characteristics; Maternal and Fetal Exposure; Medical Biomonitoring; Modification |
| تواريخ الأحداث: | Date Created: 20240709 Latest Revision: 20240710 |
| رمز التحديث: | 20240710 |
| مُعرف محوري في PubMed: | PMC11227630 |
| DOI: | 10.60787/nmj-64-6-192 |
| PMID: | 38979054 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0300-1652 |
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| DOI: | 10.60787/nmj-64-6-192 |