دورية أكاديمية
أعرض في EDS

Comparison of the therapeutic effects of lens capsular flap transplantation and autologous retinal transplantation in the management of refractory macular holes.

التفاصيل البيبلوغرافية
العنوان: Comparison of the therapeutic effects of lens capsular flap transplantation and autologous retinal transplantation in the management of refractory macular holes.
المؤلفون: Wang Q; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Xu Y; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Guo Y; Lixiang Eye Hospital of Soochow University, Suzhou, China., Zhang J; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Zhu M; Lixiang Eye Hospital of Soochow University, Suzhou, China. zhumanhuieye@126.com., Xie L; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China. xielaiqing@suda.edu.cn.
المصدر: International ophthalmology [Int Ophthalmol] 2024 Jul 09; Vol. 44 (1), pp. 324. Date of Electronic Publication: 2024 Jul 09.
نوع المنشور: Journal Article; Comparative Study
اللغة: English
بيانات الدورية: Publisher: Kluwer Country of Publication: Netherlands NLM ID: 7904294 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2630 (Electronic) Linking ISSN: 01655701 NLM ISO Abbreviation: Int Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: Dordrecht : Kluwer
Original Publication: The Hague, Junk.
مواضيع طبية MeSH: Retinal Perforations*/surgery , Retinal Perforations*/diagnosis , Retinal Perforations*/physiopathology , Visual Acuity* , Transplantation, Autologous* , Surgical Flaps* , Tomography, Optical Coherence* , Vitrectomy*/methods , Retina*/transplantation, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Aged ; Lens Capsule, Crystalline/surgery ; Lens Capsule, Crystalline/transplantation ; Treatment Outcome ; Follow-Up Studies ; Adult
مستخلص: Purpose: To report the comparison of the therapeutic effects of lens capsular flap transplantation (LCT) and autologous retinal transplantation (ART) in refractory macular hole (MH) treatment.
Methods: Thirty-one patients (31 eyes) with refractory MH were retrospectively reviewed. The patients were divided into two groups based on the surgical procedures: the LCT group (13 eyes) and the ART group (18 eyes). Patients were monitored for a minimum of 6 months. Best corrected visual acuity (BCVA), hole closure rate, postoperative central foveolar thickness (CFT), and some complications (e.g. graft loss or dislocation, postoperative retinal detachment, or postoperatively elevated intraocular pressure) were the primary outcome measures.
Results: The mean preoperative MH diameter was 1104 ± 287 μm in the LCT group and 1066 ± 297 μm in the ART group (t = 0.353, P = 0.727). The MH was closed in 12 patients (92.3%) of the LCT group and 17 patients (94.4%) of the ART group (χ 2  = 0.057, P = 0.811); the MHs of 10 patients (76.9%) in the LCT group and 11 patients (61.1%) in the ART group were completely closed (χ 2  = 0.864, P = 0.353). The BCVA improved from 2.3 ± 1.0 logMAR preoperatively to 1.3 ± 0.9 logMAR postoperatively in the LCT group and 2.3 ± 0.9 logMAR preoperatively to 1.0 ± 0.6 logMAR postoperatively in the ART group (postoperative BCVA vs preoperative BCVA in the LCT group: t = 4.374, P = 0.001; postoperative BCVA vs preoperative BCVA in the ART group: t = 5.899, P = 0.000018). The visual improvement was 1.3 ± 0.9 logMAR in the ART group and 1.0 ± 0.8 logMAR in the LCT group (t = - 1.033, P = 0.310). The postoperative CFT was 139.7 ± 48.3 μm in the LCT and 199.2 ± 25.1 μm in the ART group (t = - 4.062, P = 0.001). Graft dislocation emerged in 2 patients (15.4%) in the LCT group and 1 patient (5.6%) in the ART group.
Conclusions: Applications of LCT and ART may both enhance anatomical and visual outcomes in refractory MH cases. The ART group exhibited a more optimal postoperative CFT than the LCT group one.
(© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)
References: Ip MS, Baker BJ, Duker JS, Reichel E, Baumal CR, Gangnon R, Puliafito CA (2002) Anatomical outcomes of surgery for idiopathic macular hole as determined by optical coherence tomography. Arch Ophthalmol 120(1):29–35. https://doi.org/10.1001/archopht.120.1.29. (PMID: 10.1001/archopht.120.1.2911786054)
Michalewska Z, Michalewski J, Adelman RA, Nawrocki J (2010) Inverted internal limiting membrane flap technique for largemacular holes. Ophthalmology 117(10):2018–2025. https://doi.org/10.1016/j.ophtha.2010.02.011. (PMID: 10.1016/j.ophtha.2010.02.01120541263)
Morizane Y, Shiraga F, Kimura S, Hosokawa M, Shiode Y, Kawata T, Hosogi M, Shirakata Y, Okanouchi T (2014) Autologous transplantation of the internal limiting membrane for refractory macular holes. Am J Ophthalmol 157(4):861–869. https://doi.org/10.1016/j.ajo.2013.12.028. (PMID: 10.1016/j.ajo.2013.12.02824418265)
Chen SN, Yang CM (2016) Lens capsular flap transplantation in the management of refractory macular hole from multiple etiologies. Retina 36(1):163–170. https://doi.org/10.1097/IAE.0000000000000674. (PMID: 10.1097/IAE.000000000000067426200509)
Grewal DS, Mahmoud TH (2016) Autologous neurosensory retinal free falp closure of refractory myopic macular holes. JAMA Ophthalmol 134(2):229–230. https://doi.org/10.1001/jamaophthalmol.2015.5237. (PMID: 10.1001/jamaophthalmol.2015.523726720054)
Peiquan ZH, Jiao LY (2020) The surgical strategy of vitrectomy for refractory macular hole. Chin J Ocular Fundus Dis. https://doi.org/10.3760/cma.j.cn511434-20200622-00301. (PMID: 10.3760/cma.j.cn511434-20200622-00301)
De Novelli FJ, Preti RC, Ribeiro Monteiro ML, Pelayes DE, Junqueira Nóbrega M, Takahashi WY (2015) Autologous internal limiting membrane fragment transplantation for large, chronic, and refractory macular holes. Ophthalmic Res 55(1):45–52. https://doi.org/10.1159/000440767. (PMID: 10.1159/00044076726569390)
Rizzo S, Caporossi T, Tartaro R, Finocchio L, Franco F, Barca F, Giansanti F (2019) A human amniotic membrane plug to promote retinal breaks repair and recurrent macular hole closure. Retina 39(Suppl 1):S95–S103. https://doi.org/10.1097/IAE.0000000000002320. (PMID: 10.1097/IAE.000000000000232030312261)
Reis R, Ferreira N, Meireles A (2012) Management of stage IV macular holes: when standard surgery fails. Case Rep Ophthalmol 3(2):240–250. https://doi.org/10.1159/000342007. (PMID: 10.1159/000342007230714653457032)
Charles S, Randolph JC, Neekhra A, Salisbury CD, Littlejohn N, Calzada JI (2013) Arcuate retinotomy for the repair of large macular holes. Ophthalmic Surg Lasers Imaging Retina 44(1):69–72. https://doi.org/10.3928/23258160-20121221-15. (PMID: 10.3928/23258160-20121221-1523418735)
Peng J, Chen C, Zhang H, Zhang L, Liu J, Ren J, Zhao P (2021) Long-term surgical outcomes of lens capsular flap transplantation in the management of refractory macular hole. Retina 41(4):726–734. https://doi.org/10.1097/IAE.0000000000002922. (PMID: 10.1097/IAE.000000000000292232732611)
Peng J, Chen C, Zhang L, Huang Y, Zhang H, Zheng Y et al (2022) Lens capsular flap transplantation as primary treatment for closure of large macular holes. Retina 42(2):306–312. https://doi.org/10.1097/IAE.0000000000003315. (PMID: 10.1097/IAE.000000000000331535050929)
Peng J, Chen C, Jin H, Zhang H, Zhao P (2018) Autologous lens capsular flap transplantation combined with autologous blood application in the management of refractory macular hole. Retina 38(11):2177–2183. https://doi.org/10.1097/IAE.0000000000001830. (PMID: 10.1097/IAE.000000000000183029045320)
Wu AL, Liu YT, Chou HD, Chuang LH, Chen KJ, Chen YP et al (2021) Role of growth factors and internal limiting membrane constituents in müller cell migration. Exp Eye Res 202:108352. https://doi.org/10.1016/j.exer.2020.108352. (PMID: 10.1016/j.exer.2020.10835233166502)
Romano MR, Rossi T, Borgia A, Catania F, Sorrentino T, Ferrara M (2022) Management of refractory and recurrent macular holes: a comprehensive review. Surv Ophthalmol 67(4):908–931. https://doi.org/10.1016/j.survophthal.2022.01.006. (PMID: 10.1016/j.survophthal.2022.01.00635101550)
Moysidis SN, Koulisis N, Adrean SD, Charles S, Chetty N, Chhablani JK et al (2021) Autologous retinal transplantation for primary and refractory macular holes and macular hole retinal detachments: the global consortium. Ophthalmology 128(5):672–685. https://doi.org/10.1016/j.ophtha.2020.10.007. (PMID: 10.1016/j.ophtha.2020.10.00733045315)
Grewal DS, Charles S, Parolini B, Kadonosono K, Mahmoud TH (2019) Autologous retinal transplant for refractory macular holes: multicenter international collaborative study group. Ophthalmology 126(10):1399–1408. https://doi.org/10.1016/j.ophtha.2019.01.027. (PMID: 10.1016/j.ophtha.2019.01.02730711606)
Patel SN, Mahmoud TH, Kazahaya M, Todorich B (2021) Autologous neurosensory retinal transplantation: bridging the gap. Retina 41(12):2417–2423. https://doi.org/10.1097/IAE.0000000000003210. (PMID: 10.1097/IAE.000000000000321033990116)
Frisina R, Gius I, Tozzi L, Midena E (2022) Refractory full thickness macular hole: current surgical management. Eye 36(7):1344–1354. https://doi.org/10.1038/s41433-020-01330-y. (PMID: 10.1038/s41433-020-01330-y33479488)
معلومات مُعتمدة: SJCX23_ 1673 Postgraduate Research & Practice Innovation Program of Jiangsu Province under Grant; No.(2022)192 Gusu Health Talent Program Project in Suzhou; M2020053 the Medical Research Project of Jiangsu Provincial Health Commission under Grant; SKJY2021083 Suzhou Science and Technology Fund of China under Grant
فهرسة مساهمة: Keywords: Autologous retinal transplantation; Lens capsular flap transplantation; Refractory macular hole; Surgery
تواريخ الأحداث: Date Created: 20240709 Date Completed: 20240709 Latest Revision: 20240709
رمز التحديث: 20240709
DOI: 10.1007/s10792-024-03155-0
PMID: 38980539
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-2630
DOI:10.1007/s10792-024-03155-0