دورية أكاديمية
أعرض في EDS

Difficulty in diagnosing intracranial infection caused by Mycobacterium avium in an AIDS patient: case report and review of the literature.

التفاصيل البيبلوغرافية
العنوان: Difficulty in diagnosing intracranial infection caused by Mycobacterium avium in an AIDS patient: case report and review of the literature.
المؤلفون: Wang M; Department II of Infectious Diseases, Xixi Hospital of Hangzhou, Hangzhou Xixi Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Hangzhou, China., Cui Y; Department of Neurosurgery, Xixi Hospital of Hangzhou, Hangzhou Xixi Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Hangzhou, China., Shi J; Department II of Infectious Diseases, Xixi Hospital of Hangzhou, Hangzhou Xixi Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Hangzhou, China., Yan J; Department II of Infectious Diseases, Xixi Hospital of Hangzhou, Hangzhou Xixi Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Hangzhou, China. 18989847860@126.com.
المصدر: Diagnostic pathology [Diagn Pathol] 2024 Jul 09; Vol. 19 (1), pp. 96. Date of Electronic Publication: 2024 Jul 09.
نوع المنشور: Case Reports; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101251558 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-1596 (Electronic) Linking ISSN: 17461596 NLM ISO Abbreviation: Diagn Pathol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, 2006-
مواضيع طبية MeSH: Mycobacterium avium-intracellulare Infection*/diagnosis , Mycobacterium avium-intracellulare Infection*/microbiology , Mycobacterium avium-intracellulare Infection*/complications , AIDS-Related Opportunistic Infections*/microbiology , AIDS-Related Opportunistic Infections*/diagnosis , Mycobacterium avium Complex*/isolation & purification, Humans ; Male ; Adult ; Fatal Outcome ; Acquired Immunodeficiency Syndrome/complications ; Brain/pathology ; Brain/microbiology
مستخلص: Background: Mycobacterium avium complex (MAC) is an uncommon clinical pathogen, especially in the central nervous system (CNS), and carries a poor prognosis. MAC infections commonly present as immune reconstitution disease (IRD) in HIV patients. Herein, we report a case of intracranial infection caused by MAC in an AIDS patient without disseminated MAC (DMAC) and immune reconstitution inflammatory syndrome (IRIS).
Case Presentation: A 31-year-old HIV-positive male presented us with progressively worsening CNS symptoms, and neuroimaging revealed ring-enhancing lesions. The intracranial lesions worsened after the empirical therapy for toxoplasma encephalitis and fungal infection. Due to the rapid progression of the disease, the patient died. Mycobacterium avium was the only pathogen in brain tissue after cultures and molecular biology tests.
Conclusion: MAC infection in CNS is challenging to diagnose in HIV patients. Our findings emphasize that obtaining tissue samples and applying molecular biology methods is essential to help diagnose the patient as soon as possible to receive adequate treatment.
(© 2024. The Author(s).)
References: J Transl Med. 2007 Oct 15;5:50. (PMID: 17937815)
Ann Intern Med. 2000 Oct 3;133(7):493-503. (PMID: 11015162)
Open Forum Infect Dis. 2021 Oct 30;8(11):ofab450. (PMID: 35559128)
AIDS Rev. 2020;22(1):9-15. (PMID: 32167509)
Eur J Clin Microbiol Infect Dis. 2001 Mar;20(3):199-201. (PMID: 11347672)
MMWR Recomm Rep. 2009 Apr 10;58(RR-4):1-207; quiz CE1-4. (PMID: 19357635)
Intern Med. 2008;47(14):1349-54. (PMID: 18628585)
Ann Indian Acad Neurol. 2012 Jan;15(1):54-5. (PMID: 22412276)
Clin Infect Dis. 1996 Dec;23(6):1266-73. (PMID: 8953070)
Trop Med Health. 2023 Sep 25;51(1):54. (PMID: 37749661)
IDCases. 2014 Nov 24;2(1):19-21. (PMID: 26793442)
Can J Infect Dis Med Microbiol. 2005 May;16(3):187-9. (PMID: 18159542)
Eur J Clin Microbiol Infect Dis. 2004 Feb;23(2):142-4. (PMID: 14689317)
J Microbiol Immunol Infect. 2013 Feb;46(1):68-72. (PMID: 22227308)
Mayo Clin Proc. 2009 May;84(5):394. (PMID: 19411433)
Microbiol Spectr. 2017 Apr;5(2):. (PMID: 28429679)
J Antimicrob Chemother. 2012 Jan;67(1):222-5. (PMID: 21980068)
فهرسة مساهمة: Keywords: CNS; Case report; HIV; MAC; Mycobacterium avium
تواريخ الأحداث: Date Created: 20240709 Date Completed: 20240710 Latest Revision: 20240712
رمز التحديث: 20240712
مُعرف محوري في PubMed: PMC11232309
DOI: 10.1186/s13000-024-01515-z
PMID: 38982440
قاعدة البيانات: MEDLINE
الوصف
تدمد:1746-1596
DOI:10.1186/s13000-024-01515-z