دورية أكاديمية

Colorectal cancer and inulin supplementation: the good, the bad, and the unhelpful.

التفاصيل البيبلوغرافية
العنوان: Colorectal cancer and inulin supplementation: the good, the bad, and the unhelpful.
المؤلفون: Oliero M; Nutrition and Microbiome Laboratory, Institut du cancer de Montréal, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada., Alaoui AA; Nutrition and Microbiome Laboratory, Institut du cancer de Montréal, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada., McCartney C; Nutrition and Microbiome Laboratory, Institut du cancer de Montréal, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada., Santos MM; Nutrition and Microbiome Laboratory, Institut du cancer de Montréal, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
المصدر: Gastroenterology report [Gastroenterol Rep (Oxf)] 2024 Jul 09; Vol. 12, pp. goae058. Date of Electronic Publication: 2024 Jul 09 (Print Publication: 2024).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Oxford University Press and Science Digestive Pub. Co Country of Publication: England NLM ID: 101620508 Publication Model: eCollection Cited Medium: Print ISSN: 2052-0034 (Print) NLM ISO Abbreviation: Gastroenterol Rep (Oxf) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Oxford] : Oxford University Press and Science Digestive Pub. Co., 2013-
مستخلص: The prebiotic inulin has been vaunted for its potential to reduce the risk of colorectal cancer. Inulin fermentation resulting in the production of short-chain fatty acids, primarily butyrate, has been reported to be associated with properties that are beneficial for gut health and has led to an increased consumption of inulin in the Western population through processed food and over-the-counter dietary supplements. However, in clinical trials, there is limited evidence of the efficacy of inulin in preventing colorectal cancer. Moreover, recent data suggest that improper inulin consumption may even be harmful for gastro-intestinal health under certain circumstances. The main objective of this review is to provide insight into the beneficial and potentially detrimental effects of inulin supplementation in the context of colorectal cancer prevention and enhancement of treatment efficacy.
Competing Interests: The authors declare no conflicts of interest in this study.
(© The Author(s) 2024. Published by Oxford University Press and Sixth Affiliated Hospital of Sun Yat-sen University.)
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فهرسة مساهمة: Keywords: colorectal cancer; gut microbiota; inulin; prebiotic; short-chain fatty acids
تواريخ الأحداث: Date Created: 20240710 Latest Revision: 20240711
رمز التحديث: 20240711
مُعرف محوري في PubMed: PMC11231048
DOI: 10.1093/gastro/goae058
PMID: 38984069
قاعدة البيانات: MEDLINE
الوصف
تدمد:2052-0034
DOI:10.1093/gastro/goae058