دورية أكاديمية
Salbutamol repurposing ameliorates neuromuscular junction defects and muscle atrophy in Col6a1 -/- mouse model of collagen VI-related myopathies.
العنوان: | Salbutamol repurposing ameliorates neuromuscular junction defects and muscle atrophy in Col6a1 -/- mouse model of collagen VI-related myopathies. |
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المؤلفون: | Calabrò S; Department of Molecular Medicine, University of Padova, Padova, Italy.; Department of Biology, University of Padova, Padova, Italy., Nogara L; Department of Biomedical Sciences, University of Padova, Padova, Italy.; Venetian Institute of Molecular Medicine, Padova, Italy.; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Jian Y; Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Valentin M; Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Bizzotto D; Department of Molecular Medicine, University of Padova, Padova, Italy., Braghetta P; Department of Molecular Medicine, University of Padova, Padova, Italy., Russo L; Department of Molecular Medicine, University of Padova, Padova, Italy., Gambarotto L; Department of Molecular Medicine, University of Padova, Padova, Italy., Blaauw B; Department of Biomedical Sciences, University of Padova, Padova, Italy.; Venetian Institute of Molecular Medicine, Padova, Italy., Hashemolhosseini S; Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Bonaldo P; Department of Molecular Medicine, University of Padova, Padova, Italy., Cescon M; Department of Molecular Medicine, University of Padova, Padova, Italy. |
المصدر: | Clinical and translational medicine [Clin Transl Med] 2024 Jul; Vol. 14 (7), pp. e1688. |
نوع المنشور: | Letter; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326 (Electronic) Linking ISSN: 20011326 NLM ISO Abbreviation: Clin Transl Med Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2020- : [Hoboken, NJ] : Wiley Original Publication: Heidelberg : Springer-Verlag |
مواضيع طبية MeSH: | Disease Models, Animal* , Collagen Type VI*/genetics , Collagen Type VI*/metabolism , Muscular Atrophy*/drug therapy , Neuromuscular Junction*/drug effects, Animals ; Mice ; Muscular Diseases/drug therapy ; Muscular Diseases/genetics ; Drug Repositioning/methods |
References: | Hum Mol Genet. 2018 May 1;27(9):1556-1564. (PMID: 29462491) Neuromuscul Disord. 2013 Feb;23(2):170-5. (PMID: 23219351) Autophagy. 2015;11(12):2142-52. (PMID: 26565691) Hum Mol Genet. 1998 Dec;7(13):2135-40. (PMID: 9817932) Neurobiol Dis. 2016 Jan;85:11-24. (PMID: 26459114) Hum Mol Genet. 2019 Jul 15;28(14):2339-2351. (PMID: 31220253) Physiol Rev. 2008 Apr;88(2):729-67. (PMID: 18391178) Acta Neuropathol. 2018 Sep;136(3):483-499. (PMID: 29752552) Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5225-9. (PMID: 18362356) Autophagy. 2023 Dec;19(12):3221-3229. (PMID: 37528588) |
معلومات مُعتمدة: | #22360 AFM Telethon; University of Padova; GGP19229 Telethon Foundation; P2022Y2A3L Italian Ministry of Education, University and Research; P20227YB93 Italian Ministry of Education, University and Research; 201742SBXA Italian Ministry of Education, University and Research; HA3309/3-1 German Research Council; HA3309/6-1 German Research Council; HA3309/7-1 German Research Council; National Center for Gene Therapy and Drugs Based on RNA Technology; National Recovery and Resilience Plan (NRRP); Strengthening research structures for supporting the creation of National Centres, national R&D leaders on some Key Enabling Technologies; Project CN00000041 European Union - Next Generation EU; CUP B93D21010860004 European Union - Next Generation EU |
المشرفين على المادة: | 0 (Collagen Type VI) |
تواريخ الأحداث: | Date Created: 20240710 Date Completed: 20240710 Latest Revision: 20240712 |
رمز التحديث: | 20240712 |
مُعرف محوري في PubMed: | PMC11234414 |
DOI: | 10.1002/ctm2.1688 |
PMID: | 38984773 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2001-1326 |
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DOI: | 10.1002/ctm2.1688 |