دورية أكاديمية
Predictors of symptomatic intracerebral hemorrhage after endovascular treatment for acute ischemic stroke due to tandem lesion in anterior circulation.
| العنوان: | Predictors of symptomatic intracerebral hemorrhage after endovascular treatment for acute ischemic stroke due to tandem lesion in anterior circulation. |
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| المؤلفون: | Havlíček R; Comprehensive Stroke Center, Department of Neurology, Palacký University Medical School and University Hospital Olomouc, Czech Republic; Comprehensive Stroke Center, Department of Neurology, Central Military Hospital Prague, Czech Republic., Šaňák D; Comprehensive Stroke Center, Department of Neurology, Palacký University Medical School and University Hospital Olomouc, Czech Republic. Electronic address: daniel.sanak@centrum.cz., Černík D; Comprehensive Stroke Center, Department of Neurology, Masaryk Hospital, KZ a.s., Ústí nad Labem, Czech Republic., Neradová J; Comprehensive Stroke Center, Department of Neurology, Masaryk Hospital, KZ a.s., Ústí nad Labem, Czech Republic., Leško N; Department of Neurology, P.J. Šafarik University, Faculty of Medicine and University Hospital L. Pasteur Košice, Slovakia., Gdovinová Z; Department of Neurology, P.J. Šafarik University, Faculty of Medicine and University Hospital L. Pasteur Košice, Slovakia., Köcher M; Department of Neurology, Palacký University Medical School and University Hospital Olomouc, Czech Republic., Cihlář F; Department of Radiology, J. E. Purkinje University, Masaryk Hospital, KZ a.s., Ústí nad Labem, Czech Republic., Malik J; Department of Radiology, Central Military Hospital Prague, Czech Republic., Fedorko J; Department of Radiodiagnostics and Imaging techniques, P.J. Šafarik University, Faculty of Medicine and University Hospital L. Pasteur Košice, Slovakia., Pedowski P; Department of Radiodiagnostics and Imaging techniques, P.J. Šafarik University, Faculty of Medicine and University Hospital L. Pasteur Košice, Slovakia., Zapletalová J; Department of Biophysics and Statistics, Palacký University Medical School Olomouc, Czech Republic. |
| المصدر: | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2024 Jul 08; Vol. 33 (9), pp. 107852. Date of Electronic Publication: 2024 Jul 08. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Saunders Country of Publication: United States NLM ID: 9111633 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8511 (Electronic) Linking ISSN: 10523057 NLM ISO Abbreviation: J Stroke Cerebrovasc Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia, PA : Saunders Original Publication: New York, NY : Demos Publications, [1991- |
| مستخلص: | Background: Endovascular treatment (EVT) of tandem lesion (TL) in the anterior circulation acute ischemic stroke (IS) usually requires periprocedural antithrombotic treatment and early initiation of dual antiplatelet therapy (DAPT) after carotid stenting. However, it may contribute to an occurrence of symptomatic intracerebral hemorrhage (SICH) in some cases. We investigated factors influencing the SICH occurrence and assessed the possible predictors of SICH after EVT. Methods: IS patients with TL in the anterior circulation treated with EVT were enrolled in the multicenter retrospective ASCENT study. A good three-month clinical outcome was scored as 0-2 points in modified Rankin Scale (mRS) and recanalization using the TICI scale. SICH was assessed using the SITS-MOST criteria. Logistic regression analysis was used for the assessment of possible predictors of SICH with adjustment for potential confounders. Results: In total, 300 (68.7 % males, mean age 67.3 ± 10.2 years) patients with median of admission NIHSS 17 were analyzed. Recanalization (TICI 2b-3) was achieved in 290 (96.7 %) patients and 176 (58.7 %) had mRS 0-2. SICH occurred in 25 (8.3 %) patients. Patients with SICH did not differ from those without SICH in the rate of periprocedural antithrombotic treatment (64 vs. 57.5 %, p = 0.526) and in the rate of DAPT started within the first 12 h after EVT (20 vs. 42.2 %, p = 0.087). After adjustment, admission NIHSS and admission glycemia were found as the only predictors of SICH after EVT. Conclusion: Admission NIHSS and glycemia were found as the only predictors of SICH after EVT for TL. No associations between periprocedural antithrombotic treatment, early start of DAPT after EVT and SICH occurrence were found. Competing Interests: Declaration of competing interest All authors have no conflict of interest. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Acute ischemic stroke; Dual antiplatelet therapy; Endovascular treatment; Symptomatic intracerebral hemorrhage; Tandem lesion |
| تواريخ الأحداث: | Date Created: 20240710 Latest Revision: 20240803 |
| رمز التحديث: | 20240804 |
| DOI: | 10.1016/j.jstrokecerebrovasdis.2024.107852 |
| PMID: | 38986970 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1532-8511 |
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| DOI: | 10.1016/j.jstrokecerebrovasdis.2024.107852 |