دورية أكاديمية
Characteristics of gallbladder microbiome in healthy dogs and cats, dogs with gallbladder mucocele, and cats with suspected cholangitis/cholangiohepatitis.
| العنوان: | Characteristics of gallbladder microbiome in healthy dogs and cats, dogs with gallbladder mucocele, and cats with suspected cholangitis/cholangiohepatitis. |
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| المؤلفون: | Phumthanakorn N; Department of Pre-Clinic and Applied Animal Science (Phumthanakorn) and Department of Clinical Sciences and Public Health (Soonthornsit), Faculty of Veterinary Science (Potivanakul, Kitjarak, Lopnapun, Moonkaew, Changtrakul, Chotimol), Mahidol University, Salaya Campus, 999 Phutthamonthon Sai 4 Road Salaya, Phutthamonthon, Nakhon Pathom, Thailand., Potivanakul S; Department of Pre-Clinic and Applied Animal Science (Phumthanakorn) and Department of Clinical Sciences and Public Health (Soonthornsit), Faculty of Veterinary Science (Potivanakul, Kitjarak, Lopnapun, Moonkaew, Changtrakul, Chotimol), Mahidol University, Salaya Campus, 999 Phutthamonthon Sai 4 Road Salaya, Phutthamonthon, Nakhon Pathom, Thailand., Kitjarak S; Department of Pre-Clinic and Applied Animal Science (Phumthanakorn) and Department of Clinical Sciences and Public Health (Soonthornsit), Faculty of Veterinary Science (Potivanakul, Kitjarak, Lopnapun, Moonkaew, Changtrakul, Chotimol), Mahidol University, Salaya Campus, 999 Phutthamonthon Sai 4 Road Salaya, Phutthamonthon, Nakhon Pathom, Thailand., Lopnapun T; Department of Pre-Clinic and Applied Animal Science (Phumthanakorn) and Department of Clinical Sciences and Public Health (Soonthornsit), Faculty of Veterinary Science (Potivanakul, Kitjarak, Lopnapun, Moonkaew, Changtrakul, Chotimol), Mahidol University, Salaya Campus, 999 Phutthamonthon Sai 4 Road Salaya, Phutthamonthon, Nakhon Pathom, Thailand., Moonkaew N; Department of Pre-Clinic and Applied Animal Science (Phumthanakorn) and Department of Clinical Sciences and Public Health (Soonthornsit), Faculty of Veterinary Science (Potivanakul, Kitjarak, Lopnapun, Moonkaew, Changtrakul, Chotimol), Mahidol University, Salaya Campus, 999 Phutthamonthon Sai 4 Road Salaya, Phutthamonthon, Nakhon Pathom, Thailand., Changtrakul T; Department of Pre-Clinic and Applied Animal Science (Phumthanakorn) and Department of Clinical Sciences and Public Health (Soonthornsit), Faculty of Veterinary Science (Potivanakul, Kitjarak, Lopnapun, Moonkaew, Changtrakul, Chotimol), Mahidol University, Salaya Campus, 999 Phutthamonthon Sai 4 Road Salaya, Phutthamonthon, Nakhon Pathom, Thailand., Chotimol W; Department of Pre-Clinic and Applied Animal Science (Phumthanakorn) and Department of Clinical Sciences and Public Health (Soonthornsit), Faculty of Veterinary Science (Potivanakul, Kitjarak, Lopnapun, Moonkaew, Changtrakul, Chotimol), Mahidol University, Salaya Campus, 999 Phutthamonthon Sai 4 Road Salaya, Phutthamonthon, Nakhon Pathom, Thailand., Soonthornsit J; Department of Pre-Clinic and Applied Animal Science (Phumthanakorn) and Department of Clinical Sciences and Public Health (Soonthornsit), Faculty of Veterinary Science (Potivanakul, Kitjarak, Lopnapun, Moonkaew, Changtrakul, Chotimol), Mahidol University, Salaya Campus, 999 Phutthamonthon Sai 4 Road Salaya, Phutthamonthon, Nakhon Pathom, Thailand. |
| المصدر: | Canadian journal of veterinary research = Revue canadienne de recherche veterinaire [Can J Vet Res] 2024 Jul; Vol. 88 (3), pp. 77-86. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Canadian Veterinary Medical Association Country of Publication: Canada NLM ID: 8607793 Publication Model: Print Cited Medium: Internet ISSN: 1928-9022 (Electronic) Linking ISSN: 08309000 NLM ISO Abbreviation: Can J Vet Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Ottawa, Ont. : Canadian Veterinary Medical Association, c1986- |
| مواضيع طبية MeSH: | Dog Diseases*/microbiology , Microbiota* , Mucocele*/veterinary , Mucocele*/microbiology , Gallbladder*/microbiology , Gallbladder Diseases*/veterinary , Gallbladder Diseases*/microbiology , Cat Diseases*/microbiology, Animals ; Dogs ; Cats ; Cholangitis/veterinary ; Cholangitis/microbiology ; Bacteria/classification ; Bacteria/isolation & purification ; Bacteria/genetics ; Male ; Female |
| مستخلص: | The aim of this study was to investigate and characterize the microbiome in bile samples obtained from dogs with gallbladder mucocele (6), cats with suspected cholangitis/cholangiohepatitis (4), as well as from healthy dogs (6) and cats (4). Our goal was to compare the microbiome patterns with clinical findings and bacterial culture results in diseases of the gallbladder and to identify a potential microbial biomarker of diseased groups. The microbial taxa composition revealed that Proteobacteria were the most dominant phylum in healthy and diseased individuals in all groups. Individuals from six families including Burkholderiaceae , Phyllobacteriaceae , Bradyrhizobiaceae , Sphingomonadaceae , Moraxellaceae , and Caulobacteraceae , constituted the core microbiome in the gallbladder of healthy dogs. A combination of LEfSe analysis and Taxa2ASV decomposer revealed that Pseudomonaceae and Ruminococcaceae exclusively occurred in the mucocele group. In conclusion, this study determined the core microbiome in the gallbladder of healthy dogs and the possible biomarkers ( Pseudomonaceae and Ruminococcaceae ) of gallbladder mucocele in dogs. (Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.) |
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| فهرسة مساهمة: | Local Abstract: [Publisher, French] Le but de cette étude était d’étudier et de caractériser le microbiome dans des échantillons de bile obtenus auprès de chiens atteints de mucocèle de la vésicule biliaire (6), de chats suspectés de cholangite/cholangiohépatite (4), ainsi que de chiens (6) et de chats en bonne santé (4). Notre objectif était de comparer les modèles de microbiome avec les résultats cliniques et les résultats de cultures bactériennes dans les maladies de la vésicule biliaire et d’identifier un biomarqueur microbien potentiel des groupes malades. La composition des taxons microbiens a révélé que les protéobactéries constituaient le phylum le plus dominant chez les individus sains et malades de tous les groupes. Des individus de six familles, dont Burkholderiaceae , Phyllobacteriaceae , Bradyrhizobiaceae , Sphingomonadaceae , Moraxellaceae et Caulobacteraceae , constituaient le microbiome central de la vésicule biliaire de chiens en bonne santé. Une combinaison de l’analyse LEfSe et du décomposeur Taxa2ASV a révélé que les Pseudomonaceae et les Ruminococcaceae étaient exclusivement présentes dans le groupe des mucocèles. En conclusion, cette étude a déterminé le microbiome central de la vésicule biliaire de chiens en bonne santé et les biomarqueurs possibles ( Pseudomonaceae et Ruminococcaceae ) de la mucocèle de la vésicule biliaire chez le chien.(Traduit par Docteur Serge Messier). |
| تواريخ الأحداث: | Date Created: 20240711 Date Completed: 20240711 Latest Revision: 20240712 |
| رمز التحديث: | 20240712 |
| مُعرف محوري في PubMed: | PMC11232090 |
| PMID: | 38988335 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1928-9022 |
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