دورية أكاديمية
Interplay of Race and Neighborhood Deprivation on Resting and Ambulatory Blood Pressure in Young Adults.
| العنوان: | Interplay of Race and Neighborhood Deprivation on Resting and Ambulatory Blood Pressure in Young Adults. |
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| المؤلفون: | Jeong S; Kinesiology, Auburn University, Auburn, AL, United States., Linder BA; Department of Kinesiology, Indiana University, Bloomington, Indiana, United States., Barnett AM; Orthopaedics, University of Florida, Gainesville, FL, United States., Tharpe MA; School of Kinesiology, Auburn University, Auburn, AL, United States., Hutchison ZJ; School of Kinesiology, Auburn University, Auburn, AL, United States., Culver MN; School of Kinesiology, Auburn University, Auburn, AL, United States., Sanchez SO; Cooperative Extenison Services, Auburn University, Auburn, AL, United States., Nichols OI; Auburn University, United States., Grosicki GJ; Biodynamics and Human Performance Center, Georgia Southern University, Savannah, Georgia, United States., Bunsawat K; Department of Internal Medicine, University of Utah, Salt Lake City, UT, United States., Nasci VL; Vanderbilt University Medical Center, Nashville, United States., Gohar EY; Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN, United States., Fuller-Rowell TE; Auburn University, United States., Robinson AT; Department of Kinesiology, Indiana University, Bloomington, IN, United States. |
| المصدر: | American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2024 Jul 12. Date of Electronic Publication: 2024 Jul 12. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1539 (Electronic) Linking ISSN: 03636135 NLM ISO Abbreviation: Am J Physiol Heart Circ Physiol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Bethesda, Md. : American Physiological Society, |
| مستخلص: | Background: Nighttime BP and BP dipping (daytime-nighttime BP) are prognostic for cardiovascular disease. Compared with other racial/ethnic groups, Black Americans exhibit elevated nighttime BP and attenuated BP dipping. Neighborhood deprivation may contribute to disparities in cardiovascular health, but its effects on resting and ambulatory BP patterns in young adults is unclear. Therefore, we examined associations between neighborhood deprivation with resting and nighttime BP and BP dipping in young Black and White adults. Methods: We recruited 19 Black and 28 White participants (23 M/24 F, 21±1 years, body mass index: 26±4 kg/m 2 ) for 24-hour ambulatory BP monitoring. We assessed resting BP, nighttime BP, and BP dipping (absolute dip and nighttime:daytime BP ratio). We used the area deprivation index (ADI) to assess average neighborhood deprivation during early- and mid-childhood, and adolescence. Results: Compared with White participants, Black participants exhibited higher resting systolic and diastolic BP ( ps ≤0.029), nighttime systolic BP (114±9 vs. 108±9 mmHg, p =0.049), diastolic BP (63±8 vs. 57±7 mmHg, p =0.010), and attenuated absolute systolic BP dipping (12±5 vs. 9±7 mmHg, p =0.050). Black participants experienced greater average ADI scores compared with White participants (110(10) vs. 97(22), p =0.002), and select ADI scores correlated with resting BP and some ambulatory BP measures. Within each race, select ADI scores correlated with some BP measures for Black participants, but there were no ADI and BP correlations for White participants. Conclusions: Our findings suggest neighborhood deprivation may contribute to higher resting BP and impaired ambulatory BP patterns in young adults warranting further investigation in larger cohorts. |
| التعليقات: | Update of: medRxiv. 2023 Sep 12:2023.09.11.23295160. doi: 10.1101/2023.09.11.23295160. (PMID: 37745604) |
| معلومات مُعتمدة: | K01HL147998 HHS | National Institutes of Health (NIH); R15HL165325 HHS | National Institutes of Health (NIH); R15HL140504 HHS | National Institutes of Health (NIH); UL1TR003096 HHS | National Institutes of Health (NIH); UL1TR003096 HHS | National Institutes of Health (NIH); K99/R00DK119413 HHS | National Institutes of Health (NIH); 24PRE1201426 American Heart Association (AHA); IK2RX003670 U.S. Department of Veterans Affairs (VA); Presidential Graduate Research Fellowship Auburn University (AU) |
| فهرسة مساهمة: | Keywords: ambulatory blood pressure; cardiovascular disease; health behaviors; racial disparities; social determinants of health |
| تواريخ الأحداث: | Date Created: 20240712 Latest Revision: 20240722 |
| رمز التحديث: | 20240722 |
| DOI: | 10.1152/ajpheart.00726.2023 |
| PMID: | 38995211 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1522-1539 |
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| DOI: | 10.1152/ajpheart.00726.2023 |