دورية أكاديمية
Ethiopia National Cholera Elimination Plan 2022-2028: Experiences, Challenges, and the Way Forward.
| العنوان: | Ethiopia National Cholera Elimination Plan 2022-2028: Experiences, Challenges, and the Way Forward. |
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| المؤلفون: | Hussen M; Public Health Emergency Management, Ethiopia Public Health Institute, Addis Ababa, Ethiopia., Worku Demlie Y; Public Health Emergency Management, Ethiopia Public Health Institute, Addis Ababa, Ethiopia., Edosa M; Public Health Emergency Management, Ethiopia Public Health Institute, Addis Ababa, Ethiopia., Kebede M; Public Health Emergency Management, Ethiopia Public Health Institute, Addis Ababa, Ethiopia., Wossen M; Public Health Emergency Management, Ethiopia Public Health Institute, Addis Ababa, Ethiopia., Mulugeta Chane A; Public Health Emergency Management, Ethiopia Public Health Institute, Addis Ababa, Ethiopia., Abate G; Public Health Emergency Management, Ethiopia Public Health Institute, Addis Ababa, Ethiopia., Hailu Asfaw W; Public Health Emergency Management, Ethiopia Public Health Institute, Addis Ababa, Ethiopia., Hailu D; Clinical, Assessment, Regulatory, and Evaluation Unit, International Vaccine Institute, Seoul, Republic of Korea.; School of Public Health, Hawassa University, Hawassa, Ethiopia., Teferi M; Clinical Trials Directorate, Armauer Hansen Research Institute, Addis Ababa, Ethiopia., Jeon Y; Clinical, Assessment, Regulatory, and Evaluation Unit, International Vaccine Institute, Seoul, Republic of Korea., Gedefaw A; Clinical, Assessment, Regulatory, and Evaluation Unit, International Vaccine Institute, Seoul, Republic of Korea.; College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia., Park SE; Clinical, Assessment, Regulatory, and Evaluation Unit, International Vaccine Institute, Seoul, Republic of Korea.; Department of Global Health and Disease Control, Yonsei University Graduate School of Public Health, Seoul, Republic of Korea. |
| المصدر: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2024 Jul 12; Vol. 79 (Supplement_1), pp. S1-S7. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2011- : Oxford : Oxford University Press Original Publication: Chicago, IL : The University of Chicago Press, c1992- |
| مواضيع طبية MeSH: | Cholera*/prevention & control , Cholera*/epidemiology , Disease Outbreaks*/prevention & control , Disease Eradication*, Ethiopia/epidemiology ; Humans ; Cholera Vaccines/administration & dosage ; Cholera Vaccines/economics ; Cholera Vaccines/supply & distribution |
| مستخلص: | Cholera remains a significant public health concern in Ethiopia. More than 15.9 million Ethiopians, constituting 15% of the total population, live in areas with a history of recurrent cholera outbreaks. The last 9 years of national cholera surveillance data show the country has been experiencing cholera outbreaks every year. The current cholera outbreak, starting in August 2022, has affected the entire country, with 841 reported cases and a 3.13% case fatality rate (CFR) in 2022, and >30 000 cases with nearly a 1.4% CFR in 2023. In line with "Ending Cholera-A Global Roadmap to 2030," the government of Ethiopia is committed to eliminate cholera in the country and has prepared its "National Cholera Elimination Plan (NCP): 2022-2028" with aims to achieve zero local transmission in cholera hotspot areas by 2028 and 90% fatality reduction from the recent (2020-2022) average of 1.8% CFR. The plan is multisectoral, has a clear coordination platform, contains all interventions with in-depth situational analysis, is concordant with existing plans and strategies, and is cascaded at the regional level and implemented with existing government and public structures. Nationwide, total 118 cholera hotspot woredas (districts) were identified, and a comprehensive situation analysis of the existing cholera outbreak response capacity was assessed. This multisectoral and multiyear NCP has forecasted around US$404 million budget estimates with >90% allocated to improving the country's water, sanitation, and hygiene (US$222 million; 55% of total NCP budget) and case management (US$149 million; 37%). The cholera vaccination strategy included in the NCP exhibited a 5-year oral cholera vaccine (OCV) introduction plan with 2 doses (30 604 889 doses) and single dose (3 031 266 doses) in selected cholera hotspot areas. However, its implementation is challenged due to a lack of financial support, inability to get the requested vaccine for targeted hotspot woredas (due to the current shortage of doses in the OCV global stockpile), recurrent cholera outbreaks, and high humanitarian needs in the country. It is recommended to have a sustainable financial mechanism to support implementation, follow the requested vaccine doses, and reorganize the planned coordination platform to foster the implementation. Competing Interests: Potential conflicts of interest. The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. (© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America.) |
| References: | Clin Infect Dis. 2024 Jul 12;79(Supplement_1):S20-S32. (PMID: 38996040) Front Public Health. 2022 May 30;10:870276. (PMID: 35712321) Clin Infect Dis. 2024 Jul 12;79(Supplement_1):S33-S42. (PMID: 38996035) Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4436-4441. (PMID: 28396423) Clin Infect Dis. 2024 Jul 12;79(Supplement_1):S8-S19. (PMID: 38996039) PLoS Negl Trop Dis. 2015 Jun 04;9(6):e0003832. (PMID: 26043000) |
| معلومات مُعتمدة: | CHMTD05083-010 Korea Support Committee of the International Vaccine Institute; CHMTD05083-020 LG Electronics |
| فهرسة مساهمة: | Keywords: Cholera; Cholera Plan; Ethiopia; NCP; National Cholera Elimination Plan |
| المشرفين على المادة: | 0 (Cholera Vaccines) |
| تواريخ الأحداث: | Date Created: 20240712 Date Completed: 20240712 Latest Revision: 20240716 |
| رمز التحديث: | 20240716 |
| مُعرف محوري في PubMed: | PMC11244260 |
| DOI: | 10.1093/cid/ciae200 |
| PMID: | 38996038 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1537-6591 |
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| DOI: | 10.1093/cid/ciae200 |