دورية أكاديمية
Differential inducibility of transmembrane peptidoglycan recognition proteins (PGRPs) by bacterial challenges in the earthworm, Eisenia andrei.
| العنوان: | Differential inducibility of transmembrane peptidoglycan recognition proteins (PGRPs) by bacterial challenges in the earthworm, Eisenia andrei. |
|---|---|
| المؤلفون: | Jun Park B; Department of Life Science, Chung-Ang University, Seoul, 06974, Republic of Korea., Bin Yoon Y; Department of Life Science, Chung-Ang University, Seoul, 06974, Republic of Korea., Cheol Park S; Department of Life Science, Chung-Ang University, Seoul, 06974, Republic of Korea., Ho Lee D; Da Vinci College of General Education, Chung-Ang University, Seoul 06974, Republic of Korea., Chung D; Natural Environment Research Division, National Institute of Environmental Research, Incheon 22689, Republic of Korea., Kwak HJ; Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, Faculty of Science, Hebrew University of Jerusalem, Jerusalem 9190401, Israel., Kim JW; Department of Life Science, Chung-Ang University, Seoul, 06974, Republic of Korea. Electronic address: jungkim@cau.ac.k., Cho SJ; Department of Biological Sciences and Biotechnology, Chungbuk National University, Chungbuk 28644, Republic of Korea. Electronic address: sjchobio@chungbuk.ac.kr. |
| المصدر: | Journal of invertebrate pathology [J Invertebr Pathol] 2024 Jul 14; Vol. 206, pp. 108166. Date of Electronic Publication: 2024 Jul 14. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: United States NLM ID: 0014067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0805 (Electronic) Linking ISSN: 00222011 NLM ISO Abbreviation: J Invertebr Pathol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, NY : Academic Press Original Publication: New York. |
| مستخلص: | Peptidoglycan recognition proteins (PGRPs) and Toll-like receptors (TLRs) are highly conserved pattern recognition receptors (PRRs). Earthworms possess genes encoding TLRs that specifically respond to Gram-positive bacteria. In addition, several PGRPs have been recently identified, which are predicted to exhibit amidase activity but lack receptor function. In lophotrochozoans, a membrane-bound PRR responsible for detecting Gram-negative bacteria remains unidentified. This study reveals several novel transmembrane peptidoglycan recognition proteins (Ean-PGRPLs) in earthworms, whose mRNA expression increases in response to Gram-negative but not Gram-positive bacteria. This indicates that Ean-PGRPLs may serve as a PRR associated with intracellular signaling for Gram-negative bacteria. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| تواريخ الأحداث: | Date Created: 20240714 Latest Revision: 20240730 |
| رمز التحديث: | 20240731 |
| DOI: | 10.1016/j.jip.2024.108166 |
| PMID: | 39004164 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1096-0805 |
|---|---|
| DOI: | 10.1016/j.jip.2024.108166 |