دورية أكاديمية

Utilization of Additive Manufacturing Techniques for the Development of a Novel Scaffolds with Magnetic Properties for Potential Application in Enhanced Bone Regeneration.

التفاصيل البيبلوغرافية
العنوان: Utilization of Additive Manufacturing Techniques for the Development of a Novel Scaffolds with Magnetic Properties for Potential Application in Enhanced Bone Regeneration.
المؤلفون: Orozco-Osorio YA; Universidad Nacional de Colombia sede Medellín, Carrera 65 # 59A-100, Medellin, Antioquia, 050034, Colombia., Gaita-Anturi AV; Universidad de Antioquia, Calle 70 # 52-21, 1226, Medellín, 050010, Colombia., Ossa-Orozco CP; Universidad de Antioquia, Calle 70 # 52-21, 1226, Medellín, 050010, Colombia., Arias-Acevedo M; Instituto Tecnológico Metropolitano, Calle 73 #76A-354, Campus Robledo, Medellín, Antioquia, 50034, Colombia., Uribe D; Instituto Tecnológico Metropolitano, Calle 73 #76A-354, Campus Robledo, Medellín, Antioquia, 50034, Colombia., Paucar C; Universidad Nacional de Colombia sede Medellín, Carrera 65 # 59A-100, Medellin, Antioquia, 050034, Colombia., Vasquez AF; New Stetic, Cra. 53 #50-09, Guarne, Antioquia, 054050, Colombia., Saldarriaga W; Universidad Nacional de Colombia sede Medellín, Carrera 65 # 59A-100, Medellin, Antioquia, 050034, Colombia., Ramirez JG; Universidad Nacional de Colombia sede Medellín, Carrera 65 # 59A-100, Medellin, Antioquia, 050034, Colombia., Lopera A; Grupo de Nanoestructuras y Física Aplicada (NANOUPAR), Universidad Nacional de Colombia, La Paz, 202017, Colombia., García C; Universidad Nacional de Colombia sede Medellín, Carrera 65 # 59A-100, Medellin, Antioquia, 050034, Colombia.
المصدر: Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Jul 14, pp. e2402419. Date of Electronic Publication: 2024 Jul 14.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101235338 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1613-6829 (Electronic) Linking ISSN: 16136810 NLM ISO Abbreviation: Small Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Weinheim, Germany : Wiley-VCH, c2005-
مستخلص: This study focuses on designing and evaluating scaffolds with essential properties for bone regeneration, such as biocompatibility, macroporous geometry, mechanical strength, and magnetic responsiveness. The scaffolds are made using 3D printing with acrylic resin and iron oxides synthesized through solution combustion. Utilizing triply periodic minimal surfaces (TPMS) geometry and mask stereolithography (MSLA) printing, the scaffolds achieve precise geometrical features. The mechanical properties are enhanced through resin curing, and magnetite particles from synthesized nanoparticles and alluvial magnetite are added for magnetic properties. The scaffolds show a balance between stiffness, porosity, and magnetic responsiveness, with maximum compression strength between 4.8 and 9.2 MPa and Young's modulus between 58 and 174 MPa. Magnetic properties such as magnetic coercivity, remanence, and saturation are measured, with the best results from scaffolds containing synthetic iron oxides at 1% weight. The viscosity of the mixtures used for printing is between 350 and 380 mPas, and contact angles between 90° and 110° are achieved. Biocompatibility tests indicate the potential for clinical trials, though further research is needed to understand the impact of magnetic properties on cellular interactions and optimize scaffold design for specific applications. This integrated approach offers a promising avenue for the development of advanced materials capable of promoting enhanced bone regeneration.
(© 2024 Wiley‐VCH GmbH.)
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معلومات مُعتمدة: Project Hermes 53992. SEGUNDA CONVOCATORIA CONJUNTA DE PROYECTOS DE I+D+i EN EL MARCODE LA AGENDA REGIONAL DE I+D → i
فهرسة مساهمة: Keywords: Bone regeneration; Scaffolds; additive manufacturing; magnetic properties; material synthesis
تواريخ الأحداث: Date Created: 20240715 Latest Revision: 20240715
رمز التحديث: 20240715
DOI: 10.1002/smll.202402419
PMID: 39004887
قاعدة البيانات: MEDLINE
الوصف
تدمد:1613-6829
DOI:10.1002/smll.202402419