دورية أكاديمية
أعرض في EDS

Circadian disruption, clock genes, and metabolic health.

التفاصيل البيبلوغرافية
العنوان: Circadian disruption, clock genes, and metabolic health.
المؤلفون: Schrader LA; Molecular and Environmental Toxicology Center and., Ronnekleiv-Kelly SM; Molecular and Environmental Toxicology Center and.; Department of Surgery, Division of Surgical Oncology, School of Medicine and Public Health, University of Wisconsin, Madison Wisconsin, USA., Hogenesch JB; Divisions of Human Genetics and Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Bradfield CA; Molecular and Environmental Toxicology Center and.; Department of Oncology and., Malecki KM; Molecular and Environmental Toxicology Center and.; Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.; Division of Environmental and Occupational Health Sciences, University of Illinois Chicago, Chicago, Illinois, USA.
المصدر: The Journal of clinical investigation [J Clin Invest] 2024 Jul 15; Vol. 134 (14). Date of Electronic Publication: 2024 Jul 15.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : Ann Arbor, MI : American Society for Clinical Investigation
Original Publication: New Haven [etc.] American Society for Clinical Investigation.
مواضيع طبية MeSH: Circadian Rhythm*/genetics , CLOCK Proteins*/genetics , CLOCK Proteins*/metabolism , Diabetes Mellitus, Type 2*/genetics , Diabetes Mellitus, Type 2*/metabolism, Humans ; Animals ; Obesity/genetics ; Obesity/metabolism ; Metabolic Syndrome/genetics ; Metabolic Syndrome/metabolism ; Circadian Clocks/genetics
مستخلص: A growing body of research has identified circadian-rhythm disruption as a risk factor for metabolic health. However, the underlying biological basis remains complex, and complete molecular mechanisms are unknown. There is emerging evidence from animal and human research to suggest that the expression of core circadian genes, such as circadian locomotor output cycles kaput gene (CLOCK), brain and muscle ARNT-Like 1 gene (BMAL1), period (PER), and cyptochrome (CRY), and the consequent expression of hundreds of circadian output genes are integral to the regulation of cellular metabolism. These circadian mechanisms represent potential pathophysiological pathways linking circadian disruption to adverse metabolic health outcomes, including obesity, metabolic syndrome, and type 2 diabetes. Here, we aim to summarize select evidence from in vivo animal models and compare these results with epidemiologic research findings to advance understanding of existing foundational evidence and potential mechanistic links between circadian disruption and altered clock gene expression contributions to metabolic health-related pathologies. Findings have important implications for the treatment, prevention, and control of metabolic pathologies underlying leading causes of death and disability, including diabetes, cardiovascular disease, and cancer.
References: Sci Rep. 2019 Dec 27;9(1):20114. (PMID: 31882641)
MMWR Morb Mortal Wkly Rep. 2016 Feb 19;65(6):137-41. (PMID: 26890214)
Cell Rep. 2022 Apr 19;39(3):110703. (PMID: 35443162)
Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16219-24. (PMID: 25349387)
Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):E9247-E9256. (PMID: 30201705)
Mol Nutr Food Res. 2015 Dec;59(12):2556-64. (PMID: 26346429)
Proc Natl Acad Sci U S A. 1998 May 12;95(10):5474-9. (PMID: 9576906)
Curr Biol. 2012 May 22;22(10):939-43. (PMID: 22578422)
J Biol Chem. 1997 Mar 28;272(13):8581-93. (PMID: 9079689)
Am J Physiol Endocrinol Metab. 2020 Jan 1;318(1):E1-E10. (PMID: 31613643)
Chronobiol Int. 2006;23(1-2):497-509. (PMID: 16687322)
Science. 2010 Dec 3;330(6009):1349-54. (PMID: 21127246)
Cell. 2000 Dec 22;103(7):1009-17. (PMID: 11163178)
Cell Metab. 2012 Jun 6;15(6):848-60. (PMID: 22608008)
J Biol Chem. 2009 Apr 3;284(14):9066-73. (PMID: 19211562)
Nat Commun. 2021 May 17;12(1):2862. (PMID: 34001884)
Diabetes Obes Metab. 2015 Sep;17 Suppl 1:6-11. (PMID: 26332962)
Curr Biol. 2019 Mar 18;29(6):957-967.e4. (PMID: 30827911)
Sci Transl Med. 2018 Sep 12;10(458):. (PMID: 30209245)
Proc Natl Acad Sci U S A. 2018 May 22;115(21):5540-5545. (PMID: 29735673)
J Clin Invest. 2010 Jul;120(7):2600-9. (PMID: 20577050)
Int J Obes Relat Metab Disord. 1999 Sep;23(9):973-8. (PMID: 10490804)
Int J Obes (Lond). 2015 May;39(5):842-8. (PMID: 25601363)
Nutrients. 2020 Apr 29;12(5):. (PMID: 32365676)
Genome Med. 2017 Feb 28;9(1):19. (PMID: 28241858)
Sci Adv. 2021 Dec 03;7(49):eabg9910. (PMID: 34860550)
Nat Rev Mol Cell Biol. 2020 Feb;21(2):67-84. (PMID: 31768006)
Allergy. 2015 May;70(5):467-73. (PMID: 25689046)
J Biol Rhythms. 2019 Apr;34(2):167-177. (PMID: 30712475)
Int J Environ Res Public Health. 2022 Dec 14;19(24):. (PMID: 36554651)
Obesity (Silver Spring). 2009 Nov;17(11):2100-2. (PMID: 19730426)
Clin Endocrinol (Oxf). 2013 Dec;79(6):807-11. (PMID: 23199168)
iScience. 2020 Jun 26;23(6):101161. (PMID: 32480126)
Front Nutr. 2020 Apr 17;7:39. (PMID: 32363197)
Circulation. 2009 Oct 20;120(16):1640-5. (PMID: 19805654)
Lancet Oncol. 2019 Aug;20(8):1058-1059. (PMID: 31281097)
Front Physiol. 2019 Jun 25;10:682. (PMID: 31293431)
Biology (Basel). 2021 Dec 24;11(1):. (PMID: 35053018)
Int J Mol Sci. 2019 Mar 30;20(7):. (PMID: 30935034)
Science. 2015 Nov 6;350(6261):aac4250. (PMID: 26542580)
J Community Health. 2020 Apr;45(2):219-227. (PMID: 31489537)
Science. 2005 May 13;308(5724):1043-5. (PMID: 15845877)
PLoS One. 2016 Jan 04;11(1):e0145563. (PMID: 26726810)
Sci Transl Med. 2012 Apr 11;4(129):129ra43. (PMID: 22496545)
Science. 2001 Jan 19;291(5503):490-3. (PMID: 11161204)
Cell. 2015 Mar 26;161(1):84-92. (PMID: 25815987)
Elife. 2017 Feb 20;6:. (PMID: 28218891)
Int J Obes (Lond). 2016 Jun;40(6):899-906. (PMID: 26902807)
Metabolism. 2016 May;65(5):714-727. (PMID: 27085778)
Physiol Genomics. 2021 Aug 1;53(8):319-335. (PMID: 34056925)
Nature. 2002 May 16;417(6886):329-35. (PMID: 12015613)
J Clin Endocrinol Metab. 2015 Dec;100(12):4612-20. (PMID: 26580236)
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E682-91. (PMID: 24449876)
Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7789-7794. (PMID: 29987027)
Scand J Work Environ Health. 2014 May 1;40(3):295-304. (PMID: 24402410)
Ann Work Expo Health. 2019 Jul 24;63(6):651-665. (PMID: 30865270)
Elife. 2014 Dec 19;3:. (PMID: 25525750)
Pancreas. 2022 Jan 1;51(1):80-89. (PMID: 35195599)
J Clin Invest. 2018 Aug 31;128(9):3826-3839. (PMID: 29953415)
Cell. 2017 Nov 30;171(6):1232-1235. (PMID: 29195066)
Annu Rev Nutr. 2019 Aug 21;39:291-315. (PMID: 31180809)
Nature. 2010 Jul 29;466(7306):627-31. (PMID: 20562852)
Nutrients. 2019 May 30;11(6):. (PMID: 31151228)
J Sleep Res. 2015 Dec;24(6):639-47. (PMID: 26250860)
Obes Rev. 2018 Jan;19(1):28-40. (PMID: 28975706)
PLoS One. 2014 Nov 03;9(11):e111678. (PMID: 25365257)
J Biol Rhythms. 2011 Oct;26(5):423-33. (PMID: 21921296)
Cardiovasc Diabetol. 2016 Jan 07;15:4. (PMID: 26739996)
BMJ. 2018 Nov 21;363:k4641. (PMID: 30464025)
Nucleic Acids Res. 2013 Jul;41(12):6161-74. (PMID: 23620290)
Cell. 2006 Aug 25;126(4):801-10. (PMID: 16923398)
Nutr Metab (Lond). 2012 Sep 10;9(1):78. (PMID: 22963033)
Trends Cell Biol. 2014 Feb;24(2):90-9. (PMID: 23916625)
Chronobiologia. 1980 Jul-Sep;7(3):303-27. (PMID: 6108838)
Neurosci Lett. 2009 Feb 27;451(3):246-51. (PMID: 19159659)
Curr Biol. 2016 May 23;26(10):R432-43. (PMID: 27218855)
Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15643-8. (PMID: 20798039)
Chronobiol Int. 2020 May;37(5):673-685. (PMID: 32126839)
Nutrients. 2021 Nov 22;13(11):. (PMID: 34836433)
Cell. 1997 May 16;89(4):655-67. (PMID: 9160756)
Science. 2022 Oct 21;378(6617):276-284. (PMID: 36264811)
PLoS Biol. 2004 Nov;2(11):e377. (PMID: 15523558)
Cell Metab. 2014 Dec 2;20(6):991-1005. (PMID: 25470547)
Nat Commun. 2020 Sep 16;11(1):4643. (PMID: 32938935)
Nutrients. 2023 Jun 18;15(12):. (PMID: 37375694)
Sleep Health. 2015 Jun;1(2):115-120. (PMID: 26894229)
Front Pharmacol. 2015 Mar 24;6:50. (PMID: 25852554)
J Cell Biol. 2016 Oct 10;215(1):15-25. (PMID: 27738003)
Occup Environ Med. 2015 Feb;72(2):100-7. (PMID: 25261528)
Nutr Res Rev. 2010 Jun;23(1):155-68. (PMID: 20122305)
Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):E1132-41. (PMID: 23440187)
PLoS One. 2017 Mar 15;12(3):e0173861. (PMID: 28296937)
Am J Clin Nutr. 2015 Jan;101(1):135-43. (PMID: 25527757)
Nature. 1990 Feb 8;343(6258):536-40. (PMID: 2105471)
PLoS One. 2014 Dec 29;9(12):e114422. (PMID: 25545545)
Sleep. 2016 Feb 01;39(2):457-65. (PMID: 27091639)
J Clin Endocrinol Metab. 2015 Sep;100(9):E1255-61. (PMID: 26168277)
Yale J Biol Med. 2019 Jun 27;92(2):259-270. (PMID: 31249487)
المشرفين على المادة: EC 2.3.1.48 (CLOCK Proteins)
EC 2.3.1.48 (CLOCK protein, human)
تواريخ الأحداث: Date Created: 20240715 Date Completed: 20240715 Latest Revision: 20240717
رمز التحديث: 20240717
مُعرف محوري في PubMed: PMC11245155
DOI: 10.1172/JCI170998
PMID: 39007272
قاعدة البيانات: MEDLINE
الوصف
تدمد:1558-8238
DOI:10.1172/JCI170998