دورية أكاديمية

RANO 2.0 criteria: concepts applicable to the neuroradiologist's clinical practice.

التفاصيل البيبلوغرافية
العنوان: RANO 2.0 criteria: concepts applicable to the neuroradiologist's clinical practice.
المؤلفون: Sanvito F; UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, University of California Los Angeles, Los Angeles, California, USA., Castellano A; Neuroradiology Unit and CERMAC, IRCCS Ospedale San Raffaele Vita-Salute San Raffaele University, Milan, Italy., Cloughesy TF; UCLA Brain Tumor Program, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California., Wen PY; Center For Neuro-Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA., Ellingson BM; UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, University of California Los Angeles, Los Angeles, California, USA.
المصدر: Current opinion in oncology [Curr Opin Oncol] 2024 Jul 05. Date of Electronic Publication: 2024 Jul 05.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9007265 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-703X (Electronic) Linking ISSN: 10408746 NLM ISO Abbreviation: Curr Opin Oncol Subsets: MEDLINE
أسماء مطبوعة: Publication: Philadelphia, PA : Lippincott Williams & Wilkins
Original Publication: Philadelphia, PA : Current Science, c1989-
مستخلص: Purpose of Review: The Response Assessment in Neuro-Oncology (RANO) 2.0 criteria aim at improving the standardization and reliability of treatment response assessment in clinical trials studying central nervous system (CNS) gliomas. This review presents the evidence supporting RANO 2.0 updates and discusses which concepts can be applicable to the clinical practice, particularly in the clinical radiographic reads.
Recent Findings: Updates in RANO 2.0 were supported by recent retrospective analyses of multicenter data from recent clinical trials. As proposed in RANO 2.0, in tumors receiving radiation therapy, the post-RT MRI scan should be used as a reference baseline for the following scans, as opposed to the pre-RT scan, and radiographic findings suggesting progression within three months after radiation therapy completion should be verified with confirmatory scans. Volumetric assessments should be considered, when available, especially for low-grade gliomas, and the evaluation of nonenhancing disease should have a marginal role in glioblastoma. However, the radiographic reads in the clinical setting also benefit from aspects that lie outside RANO 2.0 criteria, such as qualitative evaluations, patient-specific clinical considerations, and advanced imaging.
Summary: While RANO 2.0 criteria are meant for the standardization of the response assessment in clinical trials, some concepts have the potential to improve patients' management in the clinical practice.
(Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
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معلومات مُعتمدة: R01 CA270027 United States CA NCI NIH HHS; R01 CA279984 United States CA NCI NIH HHS
تواريخ الأحداث: Date Created: 20240716 Latest Revision: 20240719
رمز التحديث: 20240719
DOI: 10.1097/CCO.0000000000001077
PMID: 39011735
قاعدة البيانات: MEDLINE
الوصف
تدمد:1531-703X
DOI:10.1097/CCO.0000000000001077