دورية أكاديمية

Testing the homogeneity of odds ratio across strata for combined bilateral and unilateral data.

التفاصيل البيبلوغرافية
العنوان: Testing the homogeneity of odds ratio across strata for combined bilateral and unilateral data.
المؤلفون: Hua S; Department of Biostatistics, University at Buffalo, Buffalo, New York, United States of America., Ma C; Department of Biostatistics, University at Buffalo, Buffalo, New York, United States of America.
المصدر: PloS one [PLoS One] 2024 Jul 18; Vol. 19 (7), pp. e0307276. Date of Electronic Publication: 2024 Jul 18 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Otitis Media*/diagnosis, Humans ; Odds Ratio ; Myopia/diagnosis ; Computer Simulation ; Female ; Male
مستخلص: Bilateral and unilateral combined data are commonly involved in clinical trials or observational studies designed to test the treatment effectiveness on paired organs or bodily parts within individual subjects. It is essential to examine if the treatment effect is consistent across different subgroups such as age, gender, or disease severity for understanding how the treatment works for various patient populations. In this paper, we propose three large-sample homogeneity tests of odds ratio in the stratified randomization setting using correlated combined data. Our simulation results show that the score test exhibits robust empirical type I error control and demonstrates strong power characteristics compared to other methods proposed. We apply the proposed tests to real-world datasets of acute otitis media and myopia to illustrate their practical application and utility.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Hua, Ma. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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تواريخ الأحداث: Date Created: 20240718 Date Completed: 20240718 Latest Revision: 20240720
رمز التحديث: 20240720
مُعرف محوري في PubMed: PMC11257320
DOI: 10.1371/journal.pone.0307276
PMID: 39024202
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0307276