دورية أكاديمية

Atrial fibrillation and risk of sudden cardiac arrest in young adults.

التفاصيل البيبلوغرافية
العنوان: Atrial fibrillation and risk of sudden cardiac arrest in young adults.
المؤلفون: Kim YG; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul 02841, Republic of Korea., Jeong JH; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul 02841, Republic of Korea., Han KD; Department of Statistics and Actuarial Science, Soongsil University, Seoul 06978, Republic of Korea., Roh SY; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Guro Hospital, Seoul, Republic of Korea., Lee HS; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul 02841, Republic of Korea., Choi YY; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul 02841, Republic of Korea., Shim J; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul 02841, Republic of Korea., Kim YH; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul 02841, Republic of Korea., Choi JI; Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, Seoul 02841, Republic of Korea.
المصدر: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2024 Jul 02; Vol. 26 (7).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883649 Publication Model: Print Cited Medium: Internet ISSN: 1532-2092 (Electronic) Linking ISSN: 10995129 NLM ISO Abbreviation: Europace Subsets: MEDLINE
أسماء مطبوعة: Publication: 2006- : Oxford : Oxford University Press
Original Publication: London ; Philadelphia : Saunders, c1999-
مواضيع طبية MeSH: Atrial Fibrillation*/epidemiology , Atrial Fibrillation*/diagnosis , Death, Sudden, Cardiac*/epidemiology , Death, Sudden, Cardiac*/etiology, Humans ; Male ; Female ; Adult ; Republic of Korea/epidemiology ; Young Adult ; Incidence ; Risk Factors ; Risk Assessment ; Databases, Factual ; Age Factors ; Time Factors ; Comorbidity ; Multivariate Analysis
مستخلص: Aims: Evidence of an association between atrial fibrillation (AF) and sudden cardiac arrest (SCA) in young adults is limited. In this study, we aim to evaluate this association in a general population aged between 20 and 39 years.
Methods and Results: Young adults who underwent health check-ups between 2009 and 2012 were screened from a nationwide healthcare database in South Korea. A history of AF diagnosis before the health check-ups was identified based on the relevant International Classification of Diseases, 10th edition codes reported in the database. Associations between an established diagnosis of AF and the risk of SCA during follow-up were examined. A total of 6 345 162 young people were analysed with a mean follow-up duration of 9.4 years. The mean age was 30.9 ± 5.0 years, and 5875 (0.09%) individuals were diagnosed with AF. During follow-up, SCA occurred in 5352 (0.08%) individuals, and the crude incidence was 0.56 and 0.09 events per 1000 person-years for participants with and without AF, respectively. Individuals with AF had a 3.0-fold higher risk in a multivariate model adjusted for age, sex, lifestyle, anthropometric data, and medical comorbidities (adjusted hazard ratio 2.96, 95% confidence interval 1.99-4.41, P < 0.001). Both incident and prevalent AFs were associated with an increased risk of SCA, with no significant differences between the two groups.
Conclusion: Atrial fibrillation was associated with a significantly higher risk of SCA developing in healthy young adults. Whether the rate or rhythm control influences the risk of SCA in young patients with AF remains to be examined.
(© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.)
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معلومات مُعتمدة: Korea University; KHRS2023-3 Korean Heart Rhythm Society; 2021R1A2C2011325 National Research Foundation
فهرسة مساهمة: Keywords: Atrial fibrillation; Sudden cardiac arrest; Young adults
تواريخ الأحداث: Date Created: 20240719 Date Completed: 20240727 Latest Revision: 20240729
رمز التحديث: 20240729
مُعرف محوري في PubMed: PMC11282462
DOI: 10.1093/europace/euae196
PMID: 39026436
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-2092
DOI:10.1093/europace/euae196