دورية أكاديمية
أعرض في EDS

Gestational diabetes as a risk factor for GBS maternal rectovaginal colonization: a systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Gestational diabetes as a risk factor for GBS maternal rectovaginal colonization: a systematic review and meta-analysis.
المؤلفون: Mercado-Evans V; Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS 385, Houston, TX, 77030, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, 77030, USA., Zulk JJ; Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS 385, Houston, TX, 77030, USA., Hameed ZA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS 385, Houston, TX, 77030, USA., Patras KA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS 385, Houston, TX, 77030, USA. katy.patras@bcm.edu.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX, 77030, USA. katy.patras@bcm.edu.
المصدر: BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2024 Jul 20; Vol. 24 (1), pp. 488. Date of Electronic Publication: 2024 Jul 20.
نوع المنشور: Journal Article; Systematic Review; Meta-Analysis
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967799 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2393 (Electronic) Linking ISSN: 14712393 NLM ISO Abbreviation: BMC Pregnancy Childbirth Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Diabetes, Gestational*/epidemiology , Streptococcal Infections*/epidemiology , Streptococcus agalactiae* , Vagina*/microbiology , Pregnancy Complications, Infectious*/epidemiology , Pregnancy Complications, Infectious*/microbiology , Rectum*/microbiology, Humans ; Female ; Pregnancy ; Risk Factors
مستخلص: Background: Maternal rectovaginal colonization by group B Streptococcus (GBS) increases the risk of perinatal GBS disease that can lead to death or long-term neurological impairment. Factors that increase the risk of rectovaginal GBS carriage are incompletely understood resulting in missed opportunities for detecting GBS in risk-based clinical approaches. There is a lacking consensus on whether gestational diabetes mellitus (GDM) is a risk factor for rectovaginal GBS. This systematic review and meta-analysis aims to address current conflicting findings and determine whether GDM should be clinically considered as a risk factor for maternal GBS colonization.
Methods: Peer-reviewed studies that provided GDM prevalence and documented GBS vaginal and/or rectal colonization in women with and without GDM were included in this analysis. From study inception to October 30, 2023, we identified 6,275 relevant studies from EMBASE and PUBMED of which 19 were eligible for inclusion. Eligible studies were analyzed and thoroughly assessed for risk of bias with a modified Newcastle-Ottawa Scale that interrogated representativeness and comparability of cohorts, quality of reporting for GDM and GBS status, and potential bias from other metabolic diseases. Results were synthesized using STATA 18 and analyzed using random-effects meta-analyses.
Results: Studies encompassed 266,706 women from 10 different countries, with study periods spanning from 1981 to 2020. Meta-analysis revealed that gestational diabetes is associated with a 16% increased risk of rectovaginal GBS carriage (OR 1.16, CI 1.07-1.26, P = 0.003). We also performed subgroup analyses to assess independent effects of pregestational vs. gestational diabetes on risk of maternal GBS carriage. Pregestational diabetes (Type 1 or Type 2 diabetes mellitus) was also associated with an increased risk of 76% (pooled OR 1.76, CI 1.27-2.45, P = 0.0008).
Conclusions: This study achieved a consensus among previously discrepant observations and demonstrated that gestational diabetes and pregestational diabetes are significant risk factors for maternal rectovaginal carriage of GBS. Recognition of GDM as a risk factor during clinical decisions about GBS screening and intrapartum antibiotic prophylaxis may decrease the global burden of GBS on maternal-perinatal health.
(© 2024. The Author(s).)
References: Stat Med. 2002 Jun 15;21(11):1539-58. (PMID: 12111919)
Nat Commun. 2024 Feb 3;15(1):1035. (PMID: 38310089)
Diabetes Res Clin Pract. 2022 Jan;183:109050. (PMID: 34883186)
J Obstet Gynaecol. 2019 Jul;39(5):628-632. (PMID: 30932731)
Eur J Obstet Gynecol Reprod Biol. 2021 Dec;267:274-279. (PMID: 34839249)
Infez Med. 2021 Mar 1;29(1):85-93. (PMID: 33664177)
Microbiology (Reading). 2004 Aug;150(Pt 8):2565-2573. (PMID: 15289553)
Front Cell Infect Microbiol. 2021 Apr 29;11:641005. (PMID: 33996627)
BJOG. 2020 May;127(6):680-691. (PMID: 31913562)
Obstet Gynecol. 2021 Jul 1;138(1):6-15. (PMID: 34259458)
BMC Pregnancy Childbirth. 2023 Mar 27;23(1):207. (PMID: 36973793)
Lancet Glob Health. 2022 Jun;10(6):e807-e819. (PMID: 35490693)
Am J Obstet Gynecol. 2019 Apr;220(4):324-335. (PMID: 30447213)
PLoS One. 2022 Mar 16;17(3):e0264273. (PMID: 35294459)
Acta Obstet Gynecol Scand. 1988;67(7):617-20. (PMID: 3073623)
Gut. 2018 Sep;67(9):1614-1625. (PMID: 29760169)
J Immunol Res. 2016;2016:7154524. (PMID: 27294162)
Arch Gynecol Obstet. 2019 Mar;299(3):703-711. (PMID: 30656444)
Obstet Gynecol. 2005 Dec;106(6):1246-52. (PMID: 16319248)
BMC Microbiol. 2022 Dec 21;22(1):313. (PMID: 36544085)
BMJ. 2008 Apr 26;336(7650):924-6. (PMID: 18436948)
Neonatology. 2019;115(4):301-309. (PMID: 30808831)
Obstet Gynecol. 1997 Feb;89(2):257-60. (PMID: 9015031)
BMC Infect Dis. 2018 Jul 3;18(1):291. (PMID: 29970020)
Int J Gynaecol Obstet. 2022 Jul;158(1):70-78. (PMID: 34561861)
Arch Dis Child. 2009 Sep;94(9):674-80. (PMID: 19457879)
J Med Microbiol. 2018 May;67(5):652-661. (PMID: 29543148)
Am J Perinatol. 2024 May;41(S 01):e2539-e2546. (PMID: 37557898)
Am J Reprod Immunol. 2023 Oct;90(4):e13779. (PMID: 37766411)
Pediatrics. 2016 Dec;138(6):. (PMID: 27940705)
Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4680-7. (PMID: 20534435)
Clin Microbiol Infect. 2017 Sep;23(9):673.e9-673.e16. (PMID: 28274774)
BJOG. 2019 Feb;126(3):349-358. (PMID: 29791775)
Am J Perinatol. 1992 Sep-Nov;9(5-6):425-7. (PMID: 1418148)
N Engl J Med. 2021 Mar 11;384(10):895-904. (PMID: 33704936)
Biosci Rep. 2019 Dec 20;39(12):. (PMID: 31820803)
J Matern Fetal Med. 1997 Mar-Apr;6(2):120-3. (PMID: 9086431)
Infect Dis Obstet Gynecol. 2019 Feb 3;2019:5430493. (PMID: 30853787)
Sci Rep. 2017 Aug 23;7(1):9212. (PMID: 28835692)
Lancet Infect Dis. 2016 Sep;16(9):1076-1084. (PMID: 27236858)
BMJ. 2011 Oct 18;343:d5928. (PMID: 22008217)
J Med Microbiol. 2019 May;68(5):728-740. (PMID: 31013212)
J Infect Dis. 2017 Sep 15;216(6):744-751. (PMID: 28934437)
J Korean Med Sci. 2022 Dec 12;37(48):e338. (PMID: 36513052)
Front Pediatr. 2019 Dec 10;7:513. (PMID: 31921726)
Acta Obstet Gynecol Scand. 2021 Aug;100(8):1501-1510. (PMID: 33768531)
Int J Mol Sci. 2021 Apr 20;22(8):. (PMID: 33923959)
J Med Microbiol. 2019 May;68(5):803-811. (PMID: 30994439)
Taiwan J Obstet Gynecol. 2021 Mar;60(2):262-265. (PMID: 33678325)
Obstet Gynecol. 1999 Feb;93(2):292-6. (PMID: 9932572)
Nat Rev Dis Primers. 2019 Jul 11;5(1):47. (PMID: 31296866)
BJOG. 2006 Dec;113(12):1452-8. (PMID: 17083655)
Clin Infect Dis. 2017 Nov 06;65(suppl_2):S100-S111. (PMID: 29117327)
Arch Dis Child Fetal Neonatal Ed. 2007 Jul;92(4):F271-6. (PMID: 17227807)
Eur Rev Med Pharmacol Sci. 2017 May;21(10):2303-2315. (PMID: 28617561)
BMC Med. 2021 May 27;19(1):120. (PMID: 34039350)
Front Immunol. 2017 Jun 14;8:702. (PMID: 28659928)
Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11060-5. (PMID: 26283357)
Endocrine. 2019 May;64(2):254-264. (PMID: 30421135)
معلومات مُعتمدة: AI173448 National Institute of Allergy and Infectious Diseases; R21 AI173448 United States AI NIAID NIH HHS; DK128053 United States DK NIDDK NIH HHS; AI167547 National Institute of Allergy and Infectious Diseases; GM136554 United States GM NIGMS NIH HHS; NGP10103 Burroughs Wellcome Fund; T32 GM136554 United States GM NIGMS NIH HHS; R01 DK128053 United States DK NIDDK NIH HHS; DK136201 United States DK NIDDK NIH HHS
فهرسة مساهمة: Keywords: Streptococcus agalactiae; Diabetes mellitus; Gestational diabetes; Group B Streptococcus; Neonatal outcomes; Type 1 diabetes; Type 2 diabetes; Vaginal colonization; Vaginal microbiome
تواريخ الأحداث: Date Created: 20240720 Date Completed: 20240720 Latest Revision: 20240725
رمز التحديث: 20240726
مُعرف محوري في PubMed: PMC11264770
DOI: 10.1186/s12884-024-06694-7
PMID: 39033123
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2393
DOI:10.1186/s12884-024-06694-7