دورية أكاديمية
Chemical Profile, Antibacterial Activity and Antioxidant Activity of Bark Volatile Oil of Terminalia arjuna.
| العنوان: | Chemical Profile, Antibacterial Activity and Antioxidant Activity of Bark Volatile Oil of Terminalia arjuna. |
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| المؤلفون: | Rauf M; National University of Sciences and Technology, Atta-ur-Rahman School of Applied Biosciences, NUST islamabad, Islamabad, PAKISTAN., Intisar A; University of the Punjab, Institute of Chemistry, House 2 street 2 Larechs colony 4 Mughalpura, 54840, Lahore, PAKISTAN., Manzoor S; National University of Sciences and Technology, Atta-ur-Rahman School of Applied Biosciences, NUST Islamabad, Islamabad, PAKISTAN., Qaisar U; University of the Punjab, School of biological sciences, University of the Punjab, Lahore, 54590, Lahore, PAKISTAN., Bano S; University of the Punjab, School of Chemistry, University of the Punjab, Lahore, 54590, Lahore, PAKISTAN., Ahmed E; University of the Punjab, School of chemistry, University of the Punjab, Lahore, 54590, Lahore, PAKISTAN., Mutahir Z; University of the Punjab, School of Biochemistry, University of the Punjab, Lahore, 54590, Lahore, PAKISTAN., Ain NU; University of the Punjab, Centre for Applied Molecular Biology, University of the Punjab, Lahore, 54590, Lahore, PAKISTAN. |
| المصدر: | Chemistry & biodiversity [Chem Biodivers] 2024 Jul 22, pp. e202400951. Date of Electronic Publication: 2024 Jul 22. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Zürich, Switzerland : Hoboken, NJ : Verlag Helvetica Chimica Acta ; Distributed in the USA by Wiley, c2004- |
| مستخلص: | Terminalia arjuna is an evergreen medicinal plant that belongs to the Combretaceae family of flowering plants. The bark of the plant exhibits antiviral, anticancer, hypocholesterolemic, antioxidant and antimicrobial properties. In this study, composition antibacterial activity, antioxidant activity and cytotoxicity of bark oil of Terminalia Arjuna (Roxb.) were reported. Oils were extracted by microwave assisted hydrodistillation where an oil yield of 0.18% was obtained followed by the identification of 35 compounds by gas chromatography mass spectrometry. The most abundant volatiles were furfural (11.11%), isoeugenol (9.99%), p-ethylguaiacol (9.97%), α-cadinol (9.57%), and estragole (9.47%). The oil was further evaluated against ten different drug resistant strains where oil showed significant activity against all pathogens and the highest activity was found against Acinetobacter baumannii (22mm), Klebsiella pneumoniae (22mm) and Staphylococcus aureus (22mm) in a concentration-dependent manner. Antioxidant activity evaluation demonstrated 68% radical scavenging activity by the volatile oil as compared to 81% of the standard, ascorbic acid at a concentration of 1000 μg. Cytotoxicity studies were conducted to see the effect of sample on the expression level of a housekeeping gene, Glyceraldehyde 3-phosphate dehydrogenase where it did not affect the normal transcription of the gene. (© 2024 Wiley‐VCH GmbH.) |
| فهرسة مساهمة: | Keywords: Terminalia arjuna, bark oil composition, antibacterial activity, antioxidant activity, furfural, isoeugenol |
| تواريخ الأحداث: | Date Created: 20240722 Latest Revision: 20240722 |
| رمز التحديث: | 20240722 |
| DOI: | 10.1002/cbdv.202400951 |
| PMID: | 39034926 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1612-1880 |
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| DOI: | 10.1002/cbdv.202400951 |