دورية أكاديمية
Cocoa Butter: Evolution from Natural Food Ingredient to Pharmaceutical Excipient and Drug Delivery System.
| العنوان: | Cocoa Butter: Evolution from Natural Food Ingredient to Pharmaceutical Excipient and Drug Delivery System. |
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| المؤلفون: | Loke YH; Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia., Phang HC; Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia., Mohamad N; Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia., Kee PE; Biorefinery and Bioprocessing Engineering Laboratory, Department of Chemical Engineering and Materials Science, Yuan Ze University, Taoyuan, Taiwan., Chew YL; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia., Lee SK; M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Kajang, Selangor, Malaysia., Goh CF; Discipline of Pharmaceutical Technology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Pulau Pinang, 11800, Malaysia., Yeo CI; Sunway Biofunctional Molecules Discovery Centre, School of Medical and Life Sciences, Sunway University, Malaysia., Liew KB; Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia. |
| المصدر: | Planta medica [Planta Med] 2024 Jul 23. Date of Electronic Publication: 2024 Jul 23. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: George Thieme Country of Publication: Germany NLM ID: 0066751 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0221 (Electronic) Linking ISSN: 00320943 NLM ISO Abbreviation: Planta Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Stuttgart ; New York : George Thieme Original Publication: Stuttgart, Hippokrates Verlag. |
| مستخلص: | For decades, cocoa butter has been extensively used in food industries, particularly in the production of chocolate confectioneries. The composition of fats within cocoa butter, such as stearic acid, palmitic acid, and oleic acid, determines its properties. Studies have indicated the existence of at least six polymorphic forms of cocoa butter, each possessing distinct characteristics and melting points. Recently, cocoa butter has garnered attention for its potential as a delivery system for pharmaceutical products. This review thoroughly explores cocoa butter, encompassing its production process, composition, properties, and polymorphism. It delves into its diverse applications across various industries including food, cosmetics, and pharmaceuticals. Additionally, the review investigates cocoa butter alternatives aiming to substitute cocoa butter and their roles in different drug delivery systems. The unique properties of cocoa butter have sparked interest in pharmaceutical industries, particularly since its introduction as a drug delivery system and excipient. This has prompted researchers and industry stakeholders to explore novel formulations and delivery methods, thereby expanding the range of options available to consumers in the pharmaceutical market. Competing Interests: The authors declare that they have no conflict of interest. (Thieme. All rights reserved.) |
| معلومات مُعتمدة: | DVC(R&I)/RMU/URGS/2023_007 University Research Grant Scheme (URGS) |
| تواريخ الأحداث: | Date Created: 20240723 Latest Revision: 20240723 |
| رمز التحديث: | 20240725 |
| DOI: | 10.1055/a-2359-8097 |
| PMID: | 39043195 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1439-0221 |
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| DOI: | 10.1055/a-2359-8097 |