دورية أكاديمية
أعرض في EDS

Effectiveness of Resistance Exercise on Cognitive Function in Animal Models of Alzheimer Disease: A Systematic Review and Meta-Analysis.

التفاصيل البيبلوغرافية
العنوان: Effectiveness of Resistance Exercise on Cognitive Function in Animal Models of Alzheimer Disease: A Systematic Review and Meta-Analysis.
المؤلفون: de Andrade Santos FO; Ricardo Mario Arida, Physiology Department, Federal University of São Paulo, SP, Brazil, arida@unifesp.br., Passos AA, Arida RM, Teixeira-Machado L
المصدر: The journal of prevention of Alzheimer's disease [J Prev Alzheimers Dis] 2024; Vol. 11 (4), pp. 998-1012.
نوع المنشور: Journal Article; Systematic Review; Meta-Analysis
اللغة: English
بيانات الدورية: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101638820 Publication Model: Print Cited Medium: Internet ISSN: 2426-0266 (Electronic) Linking ISSN: 22745807 NLM ISO Abbreviation: J Prev Alzheimers Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: <2018>: [Cham, Switzerland] : Springer International Publishing
Original Publication: Auzeville-Tolosane : SERDI éd., [2014]-
مواضيع طبية MeSH: Alzheimer Disease*/therapy , Alzheimer Disease*/psychology , Disease Models, Animal* , Resistance Training* , Cognition*/physiology , Physical Conditioning, Animal*, Animals
مستخلص: Aim: Alzheimer's disease (AD) is among common cause of dementia. Complementary therapies, such as resistance exercise (RE), have been proposed as an alternative for the treatment of AD. We performed a systematic review and meta-analysis to investigate the effects of RE on the cognitive function of AD animal models and their physiological mechanisms.
Methods: This review was submitted to PROSPERO (CRD42019131266) and was done according to PRISMA checklist. Four databases were used in the search: MEDLINE/PUBMED, SCOPUS, Web of Science and Google Scholar. We used SYRCLE and CAMAREDES to assess the risk of bias and methodological quality. We calculated the standardized mean difference using 95% confidence intervals and considered the random effects model and p < 0.05 to determine significance.
Key Findings: A total of 1,807 studies were founded, and after the selection process, only 11 studies were included in this review and 8 studies were included for meta-analysis. Four studies applied RE before AD induction, 7 studies applied RE after AD induction or in the AD condition. All studies included 550 adult and older animals weighing 25-280g. Our analysis revealed that RE had a positive effect on memory in AD animal models but did not show a significant impact on anxiety.
Conclusion: RE performed four or six weeks, more than three days a week, had a significant protective effect on memory. The included studies had a high risk of bias and moderate methodological quality. Therefore, RE can be a potential strategy for preventing cognitive decline in animal models.
Competing Interests: No conflict of interest.
References: Med Sci Sports Exerc. 2007 Aug;39(8):1401-7. (PMID: 17762374)
Biochem Med (Zagreb). 2012;22(3):276-82. (PMID: 23092060)
Nat Rev Neurosci. 2018 Oct;19(10):583-598. (PMID: 30194347)
Sci Rep. 2023 Feb 13;13(1):2535. (PMID: 36781881)
Syst Rev. 2016 Dec 5;5(1):210. (PMID: 27919275)
J Alzheimers Dis. 2018;61(1):359-372. (PMID: 29154278)
Brain Sci. 2023 Jul 22;13(7):. (PMID: 37509042)
Int J Mol Sci. 2020 Dec 29;22(1):. (PMID: 33383820)
Physiol Behav. 2019 Mar 15;201:42-52. (PMID: 30552921)
Hippocampus. 2016 Aug;26(8):1096-103. (PMID: 27008926)
Psychiatr Times. 2018 Nov;35(11):14-17. (PMID: 30820070)
Alzheimers Dement. 2020 Mar 10;:. (PMID: 32157811)
Ageing Res Rev. 2016 Jan;25:13-23. (PMID: 26607411)
SAGE Open Med. 2016 Jan 22;4:2050312115626731. (PMID: 26835020)
Front Psychol. 2014 Jul 10;5:753. (PMID: 25071694)
Stroke. 2004 May;35(5):1203-8. (PMID: 15060322)
BMJ. 2021 Mar 29;372:n71. (PMID: 33782057)
Mol Neurobiol. 2023 Jan;60(1):264-276. (PMID: 36261694)
Braz J Med Biol Res. 2012 Dec;45(12):1215-20. (PMID: 22930413)
J Neurosci. 2005 Apr 27;25(17):4217-21. (PMID: 15858047)
J Sport Health Sci. 2020 Sep;9(5):394-404. (PMID: 32780691)
Cell Biochem Funct. 2020 Mar;38(2):213-221. (PMID: 31978253)
Alzheimers Dement. 2023 Apr;19(4):1292-1299. (PMID: 36043526)
Int J Sports Med. 2013 Apr;34(4):368-75. (PMID: 23041964)
Exp Gerontol. 2021 Jan;143:111186. (PMID: 33279659)
Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2403-E2409. (PMID: 29463708)
J Neurochem. 2017 Jul;142(2):286-296. (PMID: 28382744)
Ann Neurosci. 2019 Jan;25(3):121-125. (PMID: 30814820)
Med Sci Sports Exerc. 2011 Jul;43(7):1334-59. (PMID: 21694556)
Front Neurosci. 2023 Apr 06;17:1132825. (PMID: 37090809)
J Cell Biol. 2018 Feb 5;217(2):459-472. (PMID: 29196460)
J Affect Disord. 2016 Jan 15;190:264-271. (PMID: 26540080)
Front Neurosci. 2023 Mar 02;17:1131214. (PMID: 36937673)
J Physiother. 2020 Jan;66(1):9-18. (PMID: 31843427)
J Neuroinflammation. 2020 Jan 3;17(1):4. (PMID: 31900170)
Braz J Med Biol Res. 2020 Oct 09;53(11):e9816. (PMID: 33053097)
Alzheimers Dement. 2018 Sep;14(9):1171-1183. (PMID: 29907423)
Med Sci Sports Exerc. 2009 Mar;41(3):687-708. (PMID: 19204579)
Neurosci Biobehav Rev. 2017 Sep;80:443-456. (PMID: 28666827)
Neurobiol Aging. 2012 Aug;33(8):1690-8. (PMID: 21741129)
Physiol Behav. 2019 Jul 1;206:206-212. (PMID: 30995451)
Br J Sports Med. 2020 Dec;54(24):1451-1462. (PMID: 33239350)
Behav Brain Res. 2017 Jun 15;328:159-177. (PMID: 28390878)
Neurosci Lett. 2022 Jan 1;766:136322. (PMID: 34737021)
Mol Neurobiol. 2017 Dec;54(10):7928-7937. (PMID: 27878552)
BMC Med Res Methodol. 2014 Mar 26;14:43. (PMID: 24667063)
Physiol Behav. 2022 Jan 1;243:113631. (PMID: 34715093)
Int J Sports Med. 2020 Oct;41(12):815-823. (PMID: 32599643)
Alzheimers Dement. 2018 Jun;14(6):775-786. (PMID: 29396107)
Science. 2018 Sep 7;361(6406):. (PMID: 30190379)
Sports Med. 2017 Dec;47(12):2521-2532. (PMID: 28819746)
J Cell Biol. 2012 Jan 23;196(2):261-76. (PMID: 22270918)
Basic Clin Neurosci. 2021 May-Jun;12(3):349-359. (PMID: 34917294)
J Sport Health Sci. 2022 Mar;11(2):212-223. (PMID: 34004389)
J Alzheimers Dis. 2020;73(4):1525-1539. (PMID: 31958083)
J Appl Physiol (1985). 2019 Jul 1;127(1):254-263. (PMID: 31120807)
J Neurosci. 2000 Jun 15;20(12):4563-72. (PMID: 10844026)
J Sports Sci Med. 2005 Sep 01;4(3):300-13. (PMID: 24453535)
فهرسة مساهمة: Keywords: Alzheimer disease; anxiety; memory; resistance exercise
تواريخ الأحداث: Date Created: 20240724 Date Completed: 20240724 Latest Revision: 20240727
رمز التحديث: 20240727
مُعرف محوري في PubMed: PMC11266263
DOI: 10.14283/jpad.2024.75
PMID: 39044511
قاعدة البيانات: MEDLINE
الوصف
تدمد:2426-0266
DOI:10.14283/jpad.2024.75