دورية أكاديمية
Study of the Acute Toxicity of Scorpion Leiurus macroctenus Venom in Rats.
| العنوان: | Study of the Acute Toxicity of Scorpion Leiurus macroctenus Venom in Rats. |
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| المؤلفون: | Gunas V; Department of Forensic Medicine and Law National Pirogov Memorial Medical University, Pyrohova Street, 56, Vinnytsia 21018, Ukraine., Maievskyi O; Department of Clinical Medicine Educational and Scientific Center 'Institute of Biology and Medicine' of Taras Shevchenko National University of Kyiv, Hlushkova Avenue, 2, Kyiv 03127, Ukraine., Raksha N; Department of Biochemistry Educational and Scientific Center 'Institute of Biology and Medicine' of Taras Shevchenko National University of Kyiv, Hlushkova Avenue, 2, Kyiv 03127, Ukraine., Vovk T; Department of Biochemistry Educational and Scientific Center 'Institute of Biology and Medicine' of Taras Shevchenko National University of Kyiv, Hlushkova Avenue, 2, Kyiv 03127, Ukraine., Savchuk O; Department of Biochemistry Educational and Scientific Center 'Institute of Biology and Medicine' of Taras Shevchenko National University of Kyiv, Hlushkova Avenue, 2, Kyiv 03127, Ukraine., Shchypanskyi S; Department of Biochemistry Educational and Scientific Center 'Institute of Biology and Medicine' of Taras Shevchenko National University of Kyiv, Hlushkova Avenue, 2, Kyiv 03127, Ukraine., Gunas I; Department of Human Anatomy National Pirogov Memorial Medical University, Pyrohova Street, 56, Vinnytsia 21018, Ukraine. |
| المصدر: | TheScientificWorldJournal [ScientificWorldJournal] 2024 Jul 17; Vol. 2024, pp. 9746092. Date of Electronic Publication: 2024 Jul 17 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Hindawi Publishing Corporation Country of Publication: United States NLM ID: 101131163 Publication Model: eCollection Cited Medium: Internet ISSN: 1537-744X (Electronic) Linking ISSN: 1537744X NLM ISO Abbreviation: ScientificWorldJournal Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York : Hindawi Publishing Corporation Original Publication: Boynton Beach, FL : Scientific World, Inc., c2001- |
| مواضيع طبية MeSH: | Scorpion Venoms*/toxicity , Scorpions*, Animals ; Rats ; Lethal Dose 50 ; Male ; Animals, Poisonous |
| مستخلص: | Background: The expansion of the territory of human habitation leads to inevitable interference in the natural range of distribution of one or another species of animals, some of which may be dangerous for human life. Scorpions-the Arachnida class and order Scorpiones-can be considered as such typical representatives. Scorpions of the Buthidae family pose a particular danger to humans. However, LD Methods and Results: 15 sexually mature scorpions were used in the study, which were kept in the same conditions and milked by a common method (electric milking). For the study, 60 male rats were used, which were injected intramuscularly with 0.5 ml of venom solution with a gradual increase in the dose (5 groups, 10 rats in each), and 10 rats were injected intramuscularly with physiological solution as control group. LD calculations were done using probit analysis method in the modification of the method by V.B. Prozorovsky. The LD Conclusions: The analysis of scientific publications and other sources of information gives reason to believe that Leiurus macroctenus has one of the highest values of LD Competing Interests: The authors have no conflicts of interest to declare. (Copyright © 2024 Valery Gunas et al.) |
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| المشرفين على المادة: | 0 (Scorpion Venoms) |
| SCR Organism: | Leiurus |
| تواريخ الأحداث: | Date Created: 20240725 Date Completed: 20240725 Latest Revision: 20240726 |
| رمز التحديث: | 20240726 |
| مُعرف محوري في PubMed: | PMC11268967 |
| DOI: | 10.1155/2024/9746092 |
| PMID: | 39050385 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1537-744X |
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| DOI: | 10.1155/2024/9746092 |