دورية أكاديمية
Clinical and immunological features of laryngeal cryptococcosis.
| عنوان ترانسليتريتد: | Clinical and immunological features of laryngeal cryptococcosis. |
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| المؤلفون: | Oliveira VF; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Moléstias Infecciosas e Parasitárias, São Paulo, São Paulo, Brazil., Taborda M; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Moléstias Infecciosas e Parasitárias, São Paulo, São Paulo, Brazil., Catarina MBS; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas Departamento de Patologia, São Paulo, São Paulo, Brazil., Kruschewsky WLL; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Moléstias Infecciosas e Parasitárias, São Paulo, São Paulo, Brazil., Rapozo MM; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Moléstias Infecciosas e Parasitárias, São Paulo, São Paulo, Brazil., Rocha TQD; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas Departamento de Patologia, São Paulo, São Paulo, Brazil., Pagliari C; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas Departamento de Patologia, São Paulo, São Paulo, Brazil., Magri ASGK; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Moléstias Infecciosas e Parasitárias, São Paulo, São Paulo, Brazil., Magri MMC; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Moléstias Infecciosas e Parasitárias, São Paulo, São Paulo, Brazil., Soto MN; Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas Departamento de Patologia, São Paulo, São Paulo, Brazil. |
| المصدر: | Revista do Instituto de Medicina Tropical de Sao Paulo [Rev Inst Med Trop Sao Paulo] 2024 Jul 08; Vol. 66, pp. e40. Date of Electronic Publication: 2024 Jul 08 (Print Publication: 2024). |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | Portuguese |
| بيانات الدورية: | Publisher: Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo Country of Publication: Brazil NLM ID: 7507484 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-9946 (Electronic) Linking ISSN: 00364665 NLM ISO Abbreviation: Rev Inst Med Trop Sao Paulo Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Sao Paulo : Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo |
| مواضيع طبية MeSH: | Cryptococcosis*/immunology , Laryngeal Diseases*/immunology , Laryngeal Diseases*/microbiology, Humans |
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| فهرسة مساهمة: | Local Abstract: [Publisher, Portuguese] The literature holds few descriptions on immune response findings for laryngeal cryptococcosis. Immunology has been more extensively described in cases involving the central nervous system and the lungs, although many of these studies were conducted in animal models. We aimed to analyze the clinical and immunological characteristics of three patients with laryngeal cryptococcosis. We observed a weak participation of the innate immune response, whereas adaptive immunity showed the predominance of a Th2-type response over a Th1-type response. Most cases occur in male older adults with immunosuppressive conditions, of which HIV infection was absent. Hoarseness configured the main symptom. We found a disease that was restricted to the larynx and possibly the lungs by contiguity. Patients with hoarseness and lesions in nasal endoscopy should be investigated for cryptococcosis by a biopsy of the larynx, including with negative serum cryptococcal antigen. The immunological aspects of our findings of laryngeal involvement resembled those in the most commonly affected systems. |
| تواريخ الأحداث: | Date Created: 20240725 Date Completed: 20240725 Latest Revision: 20240730 |
| رمز التحديث: | 20240730 |
| مُعرف محوري في PubMed: | PMC11251512 |
| DOI: | 10.1590/S1678-9946202466040 |
| PMID: | 39052027 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-9946 |
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| DOI: | 10.1590/S1678-9946202466040 |