التفاصيل البيبلوغرافية
| العنوان: |
Total Synthesis of Conjugation-Ready Hyperbranched Pentasaccharide of Clavibacter phaseoli VKM Ac-2641 T by [Au]/[Ag] Catalysis. |
| المؤلفون: |
Kumar Das P; Department of Chemistry, Indian Institute of Science Education and Research Pune, Pune 411 008, India., Hotha S; Department of Chemistry, Indian Institute of Science Education and Research Pune, Pune 411 008, India. |
| المصدر: |
Organic letters [Org Lett] 2024 Jul 25. Date of Electronic Publication: 2024 Jul 25. |
| Publication Model: |
Ahead of Print |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Washington, DC : American Chemical Society, c1999- |
| مستخلص: |
Infections by Clavibacter spp. cause an economic burden to farmers. The components present in the cell wall glycopolymers (CWGs) are important for studying the host-pathogen interactions, colonization, and infection. A pentasaccharide containing a hyperbranched Rib f -, Gal f -, and Man p - has recently been identified. Herein, we describe the first total synthesis of the conjugation-ready hyperbranched pentasaccharide of C. phaseoli VKM Ac-2641 T using the [Au]/[Ag]-catalyzed glycosidation chemistry of ethynylcyclohexyl carbonate glycosyl donors. The pentasaccharide was synthesized in a highly convergent fashion from readily accessible monosaccharide building blocks. |
| تواريخ الأحداث: |
Date Created: 20240725 Latest Revision: 20240725 |
| رمز التحديث: |
20240726 |
| DOI: |
10.1021/acs.orglett.4c02386 |
| PMID: |
39052645 |
| قاعدة البيانات: |
MEDLINE |
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