دورية أكاديمية
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Comparative Analysis of Grape Seed Oil, Linseed Oil, and a Blend: In Vivo Effects of Supplementation.

التفاصيل البيبلوغرافية
العنوان: Comparative Analysis of Grape Seed Oil, Linseed Oil, and a Blend: In Vivo Effects of Supplementation.
المؤلفون: Fernandes CDP; Graduate Program in Health and Development in the Central-West Region of Brazil, Experimental Disease Models Laboratory (LMED-Finep), Medical School, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Pott A; Laboratory of Botany, Institute of Biosciences, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Hiane PA; Graduate Program in Health and Development in the Central-West Region of Brazil, Experimental Disease Models Laboratory (LMED-Finep), Medical School, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Nascimento VAD; Graduate Program in Health and Development in the Central-West Region of Brazil, Experimental Disease Models Laboratory (LMED-Finep), Medical School, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Filiú WFO; Pharmaceutical Science, Food and Nutrition Faculty, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Oliveira LCS; Chemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Sanjinez-Argandoña EJ; School of Engineering (FAEN), Federal University of Grande Dourados (UFGD), Cidade Universitária, Dourados-Itahum Road 7 Km 12, Dourados 79804-970, Brazil., Cavalheiro LF; Chemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Nazário CED; Chemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Caires ARL; Optics and Photonics Group, Institute of Physics, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Michels FS; Optics and Photonics Group, Institute of Physics, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Freitas KC; Graduate Program in Health and Development in the Central-West Region of Brazil, Experimental Disease Models Laboratory (LMED-Finep), Medical School, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Asato MA; Medical School, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Donadon JR; Pharmaceutical Science, Food and Nutrition Faculty, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Bogo D; Graduate Program in Health and Development in the Central-West Region of Brazil, Experimental Disease Models Laboratory (LMED-Finep), Medical School, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Guimarães RCA; Graduate Program in Health and Development in the Central-West Region of Brazil, Experimental Disease Models Laboratory (LMED-Finep), Medical School, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
المصدر: Foods (Basel, Switzerland) [Foods] 2024 Jul 20; Vol. 13 (14). Date of Electronic Publication: 2024 Jul 20.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101670569 Publication Model: Electronic Cited Medium: Print ISSN: 2304-8158 (Print) Linking ISSN: 23048158 NLM ISO Abbreviation: Foods Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2012]-
مستخلص: Grape seeds are rich in bioactive substances, including polyphenols, terpenoids, and phytosterols. Linseed ( Linum usitatissimum L.) boasts a high concentration of polyunsaturated fatty acids (PUFAs), lignans, phytoestrogens, and soluble fibers, all contributing to its therapeutic potential. In this study, we pioneered the formulation of an oil blend (GL) combining grape seed oil (G) and golden linseed oil (GL) in equal volumes (1:1 ( v / v )) and we evaluated in terms of the nutritional, physical, and chemical properties and their influence in an in vivo experimental model. We analyzed the oils by performing physical-chemical analyses, examining the oxidative stability using Rancimat; conducting thermal analyses via thermogravimetry/derivative thermogravimetry (TG/DTG) and differential scanning calorimetry (DSC), performing optical UV-vis absorption analyses; examining the fluorescence emission-excitation matrix, total carotenoids, and color, and conducting metabolic assessments in an in vivo experimental trial. The fatty acid profile presented a higher fraction of linoleic acid (C18:2) in G and GL and alpha-linolenic acid (C18:3) in L. The acidity and peroxide indices were within the recommended ranges. The TG/DTG, DSC, and Rancimat analyses revealed similar behaviors, and the optical analyses revealed color variations caused by carotenoid contents in L and GL. In the in vivo trial, G (G2: 2000 mg/kg/day) promoted lower total consumption, and the blend (GL: 2000 mg/kg/day) group exhibited less weight gain per gram of consumed food. The group with G supplementation (G2: 2000 mg/kg/day) and GL had the highest levels of HDL-c. The group with L supplementation (L2: 2000 mg/kg/day) had the lowest total cholesterol level. The L2, G1 (1000 mg/kg/day), and G2 groups exhibited the lowest MCP-1 and TNF-α values. Additionally, the lowest adipocyte areas occurred in G and GL. Our results suggest that this combination is of high quality for consumption and can influence lipid profiles, markers of inflammation, and antioxidant status.
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معلومات مُعتمدة: 001 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
فهرسة مساهمة: Keywords: alpha-linolenic acid; cytokines; fatty acids; linolenic acid; seed oil
تواريخ الأحداث: Date Created: 20240727 Latest Revision: 20240729
رمز التحديث: 20240729
مُعرف محوري في PubMed: PMC11276530
DOI: 10.3390/foods13142283
PMID: 39063367
قاعدة البيانات: MEDLINE
الوصف
تدمد:2304-8158
DOI:10.3390/foods13142283