دورية أكاديمية

Gender Differences in the Diagnosis of Chronic Obstructive Pulmonary Disease after Spirometry.

التفاصيل البيبلوغرافية
العنوان: Gender Differences in the Diagnosis of Chronic Obstructive Pulmonary Disease after Spirometry.
المؤلفون: Moffett AT; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA., Halpern SD; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USAs.; Department of Medical Ethics and Health Policy, University of Pennsylvania, Philadelphia, PA, USA., Weissman GE; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USAs.
المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Jul 19. Date of Electronic Publication: 2024 Jul 19.
نوع المنشور: Journal Article; Preprint
اللغة: English
بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
مستخلص: Background: Women are more likely than men to report delays in the diagnosis of chronic obstructive pulmonary disease (COPD), though the etiology of these delays is unknown. We sought to test whether delays in COPD diagnosis persist after the performance of spirometry.
Methods: We used the Optum Labs Data Warehouse to identify patients 18 years of age and older without a prior diagnosis of COPD, with a post-bronchodilator forced expiratory volume in 1 second (FEV 1 ) to forced vital capacity (FVC) ratio of less than 0.7 on spirometry. We used a Cox proportional hazards model to compare the time to diagnosis after spirometry in men and women, adjusting for age, race, ethnicity, tobacco use, and post-bronchodilator FEV 1 /FVC.
Results: The probability of receiving a COPD diagnosis after the performance of spirometry was lower among women than men (adjusted hazard ratio [aHR] 0.66, 95% confidence interval [CI] 0.50 to 0.88).
Conclusion: In this retrospective cohort study of patients with spirometric evidence of obstruction, the time to diagnosis of COPD was greater among women than men. While previous vignette-based studies have found that gender differences in the diagnosis of COPD resolve with the performance of spirometry, we found that gender differences persist after spirometry has been performed. Clinicians were less likely to diagnose COPD in women even when spirometry supported this diagnosis.
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معلومات مُعتمدة: F32 HL167456 United States HL NHLBI NIH HHS
تواريخ الأحداث: Date Created: 20240729 Latest Revision: 20240801
رمز التحديث: 20240801
مُعرف محوري في PubMed: PMC11275668
DOI: 10.1101/2024.07.18.24310648
PMID: 39072031
قاعدة البيانات: MEDLINE
الوصف
DOI:10.1101/2024.07.18.24310648