دورية أكاديمية
Examining the Difficulties in Identifying and Handling Cardiac Amyloidosis; Acquiring Important Knowledge and Robust Treatment Methods.
| العنوان: | Examining the Difficulties in Identifying and Handling Cardiac Amyloidosis; Acquiring Important Knowledge and Robust Treatment Methods. |
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| المؤلفون: | Saleh Ali GM; School of Pharmacy, RK University, Kasturbadham, Rajkot, Gujarat, 360020, India., Emmanuel Seme WA; School of Pharmacy, RK University, Kasturbadham, Rajkot, Gujarat, 360020, India., Dudhat K; School of Pharmacy, RK University, Kasturbadham, Rajkot, Gujarat, 360020, India. |
| المصدر: | Cardiovascular & hematological disorders drug targets [Cardiovasc Hematol Disord Drug Targets] 2024 Jul 23. Date of Electronic Publication: 2024 Jul 23. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101269160 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-4063 (Electronic) Linking ISSN: 1871529X NLM ISO Abbreviation: Cardiovasc Hematol Disord Drug Targets Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Sharjah, U.A.E. ; San Francisco, CA : Bentham Science Publishers, [2006]- |
| مستخلص: | Systemic amyloidosis is a rare protein misfolding and deposition condition that causes slow organ failure. Each of the more than 15 exclusive sorts of systemic amyloidosis, which encourage amyloid production and tissue deposition, is introduced by a unique precursor protein. Amyloidosis can affect various organs, including the heart, kidneys, liver, nerves, gastrointestinal tract, lungs, muscles, skin, and soft tissues. It can either be acquired or hereditary. Insidious and doubtful signs often cause a put-off in diagnosis. In the closing decade, noteworthy progressions have been made in the identity, prediction, and handling of amyloidosis. Shotgun proteomics based on mass spectrometry has revolutionized amyloid typing and enabled the identification of novel amyloid forms. It is critical to correctly identify the precursor protein implicated in amyloidosis because the kind of protein influences the proper treatment strategy. Cardiac amyloidosis is a disorder characterized by the systemic accumulation of amyloid protein in the myocardium's extracellular space, which causes a variety of symptoms. The buildup of amyloid aggregates precipitates myocardial thickening and stiffening, culminating in diastolic dysfunction and, in due course, heart failure. We examine every kind of systemic amyloidosis in this text to offer practitioners beneficial equipment for diagnosing and treating those unusual diseases. This review presents a comprehensive analysis of cardiac amyloidosis and consolidates current methods for screening, diagnosis, evaluation, and treatment alternatives. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| فهرسة مساهمة: | Keywords: AL amyloidosis therapy; ATTR amyloidosis; Cardiac amyloidosis; cardiac biomarker |
| تواريخ الأحداث: | Date Created: 20240730 Latest Revision: 20240730 |
| رمز التحديث: | 20240730 |
| DOI: | 10.2174/011871529X301954240715041558 |
| PMID: | 39075963 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2212-4063 |
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| DOI: | 10.2174/011871529X301954240715041558 |