دورية أكاديمية
Laboratory profiling of patients with long COVID in the Brazilian Amazon region: A cross-sectional study.
| العنوان: | Laboratory profiling of patients with long COVID in the Brazilian Amazon region: A cross-sectional study. |
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| المؤلفون: | Galúcio VCA; Centre for Biological Health Sciences, State University of Pará (UEPA), Belém, Brazil., de Menezes DC; Centre for Biological Health Sciences, State University of Pará (UEPA), Belém, Brazil., Chaves ECR; Centre for Biological Health Sciences, State University of Pará (UEPA), Belém, Brazil., van den Berg AVS; Centre for Biological Health Sciences, State University of Pará (UEPA), Belém, Brazil., de Lima PDL; Centre for Biological Health Sciences, State University of Pará (UEPA), Belém, Brazil., da Costa Vasconcelos PF; Centre for Biological Health Sciences, State University of Pará (UEPA), Belém, Brazil., Quaresma JAS; Centre for Biological Health Sciences, State University of Pará (UEPA), Belém, Brazil.; School of Medicine, São Paulo University (USP), São Paulo, Brazil.; Tropical Medicine Centre, Federal University of Pará (UFPA), Belém, Brazil., Falcão LFM; Centre for Biological Health Sciences, State University of Pará (UEPA), Belém, Brazil.; School of Medicine, São Paulo University (USP), São Paulo, Brazil. |
| المصدر: | Journal of medical virology [J Med Virol] 2024 Aug; Vol. 96 (8), pp. e29828. |
| نوع المنشور: | Journal Article; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York Ny : Wiley-Liss Original Publication: New York, Liss. |
| مواضيع طبية MeSH: | COVID-19*/blood , COVID-19*/epidemiology , COVID-19*/diagnosis, Humans ; Brazil/epidemiology ; Cross-Sectional Studies ; Male ; Female ; Middle Aged ; Aged ; Adult ; SARS-CoV-2 ; Hospitalization/statistics & numerical data ; C-Reactive Protein/analysis ; Aged, 80 and over |
| مستخلص: | The condition commonly referred to as long coronavirus disease (COVID) is characterized by the continuation of symptoms, sometimes accompanied by new symptoms that persist after the resolution of acute coronavirus disease 2019 (COVID-19). This observational cross-sectional study investigated 332 patients with long COVID in the Brazilian Amazon region. The study aimed to elucidate the systemic interactions associated with long COVID by compiling the findings related to hematological, coagulation, immunological, metabolic, hepatic, renal, and muscular profiles. Participants with long COVID were identified using rigorous criteria and underwent thorough laboratory examinations. The obtained data were subsequently analyzed, allowing for comparisons, associations, and correlations between findings within distinct groups in the study. Significant associations were observed between hospitalization during the acute phase and persistent laboratory abnormalities, suggesting a potential link between acute severity and long-term effects. Notably, individuals with long COVID for over a year exhibited elevated levels of monocytes, prolonged prothrombin times, reduced prothrombin activity, high levels of lactate dehydrogenase, and an increased frequency of qualitative C-reactive protein detection. This study provides valuable insights into the laboratory risk profile of patients with long COVID, particularly in the unique context of the Amazon region, where patients exhibit persistent symptoms lasting up to 1261 days. (© 2024 Wiley Periodicals LLC.) |
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| معلومات مُعتمدة: | 006/2020 Amazon Foundation for Research Support (FAPESPA); 09/2021 Secretary of Science, Technology, and Higher, Professional and Technological Education (SECTET); 13/2020 Coordination for the Improvement of Higher Education Personnel-Brazil (CAPES); 406360/2022-7 National Council for Scientific and Technological Development-Brazil (CNPq) |
| فهرسة مساهمة: | Keywords: biomarkers; hematological tests; laboratory markers; long COVID |
| المشرفين على المادة: | 9007-41-4 (C-Reactive Protein) |
| تواريخ الأحداث: | Date Created: 20240731 Date Completed: 20240731 Latest Revision: 20240731 |
| رمز التحديث: | 20240731 |
| DOI: | 10.1002/jmv.29828 |
| PMID: | 39081145 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1096-9071 |
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| DOI: | 10.1002/jmv.29828 |