دورية أكاديمية
The immediate metabolomic effects of whole-genome duplication in the greater duckweed, Spirodela polyrhiza.
| العنوان: | The immediate metabolomic effects of whole-genome duplication in the greater duckweed, Spirodela polyrhiza. |
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| المؤلفون: | Wu T; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, 9000, Belgium.; VIB Center for Plant Systems Biology, VIB, Ghent, 9052, Belgium., Bafort Q; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, 9000, Belgium.; VIB Center for Plant Systems Biology, VIB, Ghent, 9052, Belgium.; Department of Biology, Ghent University, Ghent, 9000, Belgium., Mortier F; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, 9000, Belgium.; VIB Center for Plant Systems Biology, VIB, Ghent, 9052, Belgium.; Department of Biology, Ghent University, Ghent, 9000, Belgium., Almeida-Silva F; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, 9000, Belgium.; VIB Center for Plant Systems Biology, VIB, Ghent, 9052, Belgium., Natran A; VIB Center for Plant Systems Biology, VIB, Ghent, 9052, Belgium., Van de Peer Y; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, 9000, Belgium.; VIB Center for Plant Systems Biology, VIB, Ghent, 9052, Belgium.; College of Horticulture, Academy for Advanced Interdisciplinary Studies, Nanjing Agricultural University Biochemistry, Nanjing, 210095, China.; Centre for Microbial Ecology and Genomics, Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, 0028, South Africa. |
| المصدر: | American journal of botany [Am J Bot] 2024 Aug; Vol. 111 (8), pp. e16383. Date of Electronic Publication: 2024 Aug 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 0370467 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-2197 (Electronic) Linking ISSN: 00029122 NLM ISO Abbreviation: Am J Bot Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2018-> : [Philadelphia, PA] : Wiley Original Publication: Baltimore Md : Botanical Society Of America |
| مواضيع طبية MeSH: | Araceae*/genetics , Araceae*/metabolism , Genome, Plant* , Metabolomics* , Gene Duplication*, Metabolome ; Polyploidy ; Biomass |
| مستخلص: | Premise: In plants, whole-genome duplication (WGD) is a common mutation with profound evolutionary potential. Given the costs associated with a superfluous genome copy, polyploid establishment is enigmatic. However, in the right environment, immediate phenotypic changes following WGD can facilitate establishment. Metabolite abundances are the direct output of the cell's regulatory network and determine much of the impact of environmental and genetic change on the phenotype. While it is well known that an increase in the bulk amount of genetic material can increase cell size, the impact of gene dosage multiplication on the metabolome remains largely unknown. Methods: We used untargeted metabolomics on four genetically distinct diploid-neoautotetraploid pairs of the greater duckweed, Spirodela polyrhiza, to investigate how WGD affects metabolite abundances per cell and per biomass. Results: Autopolyploidy increased metabolite levels per cell, but the response of individual metabolites varied considerably. However, the impact on metabolite level per biomass was restricted because the increased cell size reduced the metabolite concentration per cell. Nevertheless, we detected both quantitative and qualitative effects of WGD on the metabolome. Many effects were strain-specific, but some were shared by all four strains. Conclusions: The nature and impact of metabolic changes after WGD depended strongly on the genotype. Dosage effects have the potential to alter the plant metabolome qualitatively and quantitatively, but were largely balanced out by the reduction in metabolite concentration due to an increase in cell size in this species. (© 2024 Botanical Society of America.) |
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| معلومات مُعتمدة: | 833522 International ERC_ European Research Council |
| فهرسة مساهمة: | Keywords: Araceae; Lemnaceae; Spirodela polyrhiza; comparative metabolomics; dosage effects; duckweed; polyploidy; whole genome duplication (WGD) |
| تواريخ الأحداث: | Date Created: 20240801 Date Completed: 20240823 Latest Revision: 20240829 |
| رمز التحديث: | 20240830 |
| مُعرف محوري في PubMed: | PMC7616399 |
| DOI: | 10.1002/ajb2.16383 |
| PMID: | 39087852 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1537-2197 |
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| DOI: | 10.1002/ajb2.16383 |