دورية أكاديمية
أعرض في EDS

The effect of carbomer versus noncarbomer lubricant on the adequacy of cervical cytology specimens.

التفاصيل البيبلوغرافية
العنوان: The effect of carbomer versus noncarbomer lubricant on the adequacy of cervical cytology specimens.
المؤلفون: Lander ME; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address: mlander221@gmail.com., Feldman K; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Summit Health, Yonkers, New York., Perlman B; Department of Reproductive Endocrinology and Infertility, Damien Fertility Partners, Shrewsbury, New Jersey., Greenberg P; Biostatistics and Epidemiology Services Center, Rutgers School of Public Health, Piscataway, New Jersey., Heller DS; Department of Pathology, Rutgers, New Jersey Medical School, Newark, New Jersey., Einstein MH; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Rutgers, New Jersey Medical School, Newark, New Jersey., Marcus JZ; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois.
المصدر: Journal of the American Society of Cytopathology [J Am Soc Cytopathol] 2024 Jul 09. Date of Electronic Publication: 2024 Jul 09.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101613234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2945 (Print) Linking ISSN: 22132953 NLM ISO Abbreviation: J Am Soc Cytopathol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Elsevier
مستخلص: Introduction: Cervical cytology remains a critical screening tool for cervical cancer. While various factors can influence cytology quality, the effect of lubricant type used during specimen collection has been previously studied with inconclusive results. This study aimed to evaluate the impact of surgical lubricant on cervical cytology results and elucidate risk factors associated with unsatisfactory results. We hypothesized that switching from a carbomer-containing lubricant to a noncarbomer, water-soluble lubricant would improve specimen adequacy in cervical cytology.
Materials and Methods: A retrospective chart review was performed examining patient cytologic results from January to December 2017 at a single academic institution. After historical rates of unsatisfactory cytology were higher than acceptable standards, the practice changed lubricant formulation from a carbomer containing lubricant to a noncarbomer, water soluble lubricant. Demographic data and treatment characteristics were collected for eligible patients. Matched analysis was performed to examine factors associated with an unsatisfactory cytology result.
Results: After the change in lubricant, there was a significant decline in the rates of unsatisfactory cytology from 9.6% to 5.7%, P = 0.01. This decline was also observed when patients were matched based on menopausal status, personal history of gynecologic malignancy, pregnancy status, and cytology specimen type (10.0% to 4.8%, P = 0.001).
Conclusions: Change in lubricant from a carbomer containing to noncarbomer, water soluble product was associated with a statistically significant decline in the rates of unsatisfactory cytology. Although prior data have had mixed results as to the etiology of unsatisfactory cytology, we feel that this directly contributed to the high rates observed at our institution.
(Copyright © 2024 American Society of Cytopathology. Published by Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Carbomer; Cervical cytology; Lubricant; Pap smear; Unsatisfactory
تواريخ الأحداث: Date Created: 20240802 Latest Revision: 20240802
رمز التحديث: 20240803
DOI: 10.1016/j.jasc.2024.07.003
PMID: 39095272
قاعدة البيانات: MEDLINE
الوصف
تدمد:2213-2945
DOI:10.1016/j.jasc.2024.07.003