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Brain Perception of Different Oils on Appetite Regulation: An Anorectic Gene Expression Pattern in the Hypothalamus Dependent on the Vagus Nerve.

التفاصيل البيبلوغرافية
العنوان: Brain Perception of Different Oils on Appetite Regulation: An Anorectic Gene Expression Pattern in the Hypothalamus Dependent on the Vagus Nerve.
المؤلفون: Lopes GCA; Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil., Miranda BCR; Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil., Lima JOPF; Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil., Martins JA; Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil., de Sousa AA; Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil., Nobre TA; Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil., Severo JS; Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil., da Silva TEO; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo 17012-900, SP, Brazil., Afonso MDS; Department of Inflammation and Fibrosis, Gilead Sciences, Foster City, CA 94404, USA., Lima JDCC; Cancer Metabolism Research Group, Department of Surgery and LIM26-HCFMUSP, Faculty of Medicine, University of São Paulo, São Paulo 17012-900, SP, Brazil., de Matos Neto EM; Department of Physical Education, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Torres LRO; Federal Institute of Education, Science and Technology of Maranhão, Caxias 65030-005, MA, Brazil., Cintra DE; Laboratory of Nutritional Genomics, University of Campinas, Campinas 13083-855, SP, Brazil.; Nutrigenomics and Lipids Research Center, CELN, School of Applied Sciences University of Campinas, São Paulo 13083-970, SP, Brazil.; Hospital Israelita Albert Einstein (HIAE), São Paulo 05652-900, SP, Brazil., Lottenberg AM; Nutrigenomics and Lipids Research Center, CELN, School of Applied Sciences University of Campinas, São Paulo 13083-970, SP, Brazil.; Hospital Israelita Albert Einstein (HIAE), São Paulo 05652-900, SP, Brazil.; Laboratório de Lípides (LIM10), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, University of São Paulo, São Paulo 17012-900, SP, Brazil., Seelaender M; Cancer Metabolism Research Group, Department of Surgery and LIM26-HCFMUSP, Faculty of Medicine, University of São Paulo, São Paulo 17012-900, SP, Brazil., Silva MTBD; Institute of Biomedical Sciences Abel Salazar, Center for Drug Discovery and Innovative Medicines, Laboratory of Physiology, Department of Immuno-Physiology and Pharmacology, University of Porto, 4099-002 Porto, Portugal., Torres-Leal FL; Metabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina 64049-550, PI, Brazil.
المصدر: Nutrients [Nutrients] 2024 Jul 24; Vol. 16 (15). Date of Electronic Publication: 2024 Jul 24.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Vagus Nerve*/drug effects , Vagus Nerve*/physiology , Hypothalamus*/metabolism , Hypothalamus*/drug effects , Olive Oil*/pharmacology , Neuropeptide Y*/genetics , Neuropeptide Y*/metabolism , Palm Oil*/pharmacology , Appetite Regulation*/drug effects , Soybean Oil*/administration & dosage , Soybean Oil*/pharmacology, Animals ; Male ; Rats, Wistar ; Linseed Oil/pharmacology ; Rats ; Eating/drug effects ; Plant Oils/pharmacology ; Pro-Opiomelanocortin/genetics ; Pro-Opiomelanocortin/metabolism ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Gastrointestinal Motility/drug effects ; Gene Expression Regulation/drug effects ; RNA, Messenger/metabolism ; RNA, Messenger/genetics
مستخلص: (1) Background: We examined the effect of the acute administration of olive oil (EVOO), linseed oil (GLO), soybean oil (SO), and palm oil (PO) on gastric motility and appetite in rats. (2) Methods: We assessed food intake, gastric retention (GR), and gene expression in all groups. (3) Results: Both EVOO and GLO were found to enhance the rate of stomach retention, leading to a decrease in hunger. On the other hand, the reduction in food intake caused by SO was accompanied by delayed effects on stomach retention. PO caused an alteration in the mRNA expression of NPY, POMC, and CART. Although PO increased stomach retention after 180 min, it did not affect food intake. It was subsequently verified that the absence of an autonomic reaction did not nullify the influence of EVOO in reducing food consumption. Moreover, in the absence of parasympathetic responses, animals that received PO exhibited a significant decrease in food consumption, probably mediated by lower NPY expression. (4) Conclusions: This study discovered that different oils induce various effects on parameters related to food consumption. Specifically, EVOO reduces food consumption primarily through its impact on the gastrointestinal tract, making it a recommended adjunct for weight loss. Conversely, the intake of PO limits food consumption in the absence of an autonomic reaction, but it is not advised due to its contribution to the development of cardiometabolic disorders.
References: Nat Commun. 2018 Aug 24;9(1):3432. (PMID: 30143607)
J Pharm Pharmacol. 2008 Jan;60(1):63-70. (PMID: 18088506)
Physiol Rep. 2015 Feb 12;3(2):. (PMID: 25677547)
Nutrition. 2006 Feb;22(2):197-205. (PMID: 16459232)
Science. 2018 Nov 16;362(6416):. (PMID: 30385464)
Physiol Behav. 2004 Apr;81(2):249-73. (PMID: 15159171)
Eur J Pharmacol. 2020 Jun 15;877:173087. (PMID: 32234430)
Int J Mol Sci. 2023 Feb 06;24(4):. (PMID: 36834616)
Foods. 2019 Dec 03;8(12):. (PMID: 31816909)
Endocr Rev. 2022 Mar 9;43(2):314-328. (PMID: 34490882)
J Dairy Sci. 2016 Feb;99(2):1161-1172. (PMID: 26627858)
Am J Physiol Gastrointest Liver Physiol. 2013 Apr 15;304(8):G708-14. (PMID: 23370677)
Front Endocrinol (Lausanne). 2019 Jan 04;9:754. (PMID: 30662430)
Am J Clin Nutr. 1998 Dec;68(6):1157-73. (PMID: 9846842)
Theranostics. 2020 Jul 9;10(18):8197-8210. (PMID: 32724466)
Neurogastroenterol Motil. 2017 May;29(5):. (PMID: 27781333)
Gut. 1988 Mar;29(3):306-11. (PMID: 3356362)
Mol Metab. 2022 May;59:101455. (PMID: 35167990)
Neuroscience. 2020 Dec 15;451:164-173. (PMID: 33002557)
PLoS One. 2022 Mar 17;17(3):e0264321. (PMID: 35298484)
Cell Metab. 2021 Mar 2;33(3):676-687.e5. (PMID: 33450178)
Crit Rev Food Sci Nutr. 2022;62(8):2235-2249. (PMID: 33261509)
Nutrients. 2018 Oct 07;10(10):. (PMID: 30301241)
Biomed Pharmacother. 2002 Oct;56(8):365-79. (PMID: 12442909)
Neuroimage. 2008 Feb 15;39(4):1824-31. (PMID: 18155924)
Front Nutr. 2019 Nov 12;6:170. (PMID: 31781572)
Am J Physiol Endocrinol Metab. 2019 Oct 1;317(4):E559-E572. (PMID: 31310579)
Life Sci. 2021 Feb 15;267:118972. (PMID: 33383052)
Biochem Res Int. 2022 Feb 21;2022:9394356. (PMID: 35237451)
Nutrients. 2014 Apr 02;6(4):1364-73. (PMID: 24699194)
Ann Nutr Metab. 2003;47(3-4):132-8. (PMID: 12743464)
Pathology. 2019 Feb;51(2):131-141. (PMID: 30522787)
Molecules. 2021 Nov 26;26(23):. (PMID: 34885769)
Brain Res. 2004 Apr 23;1006(1):100-6. (PMID: 15047028)
Front Endocrinol (Lausanne). 2022 Oct 28;13:932761. (PMID: 36387867)
Front Cell Neurosci. 2018 Sep 03;12:276. (PMID: 30233321)
Cell Metab. 2023 Jun 6;35(6):979-995.e7. (PMID: 37201523)
Sci Rep. 2023 Apr 5;13(1):5556. (PMID: 37019935)
Inflamm Res. 2019 Nov;68(11):915-932. (PMID: 31363792)
J Integr Neurosci. 2022 Mar 18;21(2):47. (PMID: 35364635)
Front Physiol. 2020 Feb 11;11:61. (PMID: 32116771)
Turk J Biol. 2020 Dec 14;44(6):437-448. (PMID: 33402870)
Brain Sci. 2020 Jun 19;10(6):. (PMID: 32575391)
Lab Pract. 1973 Jul;22(6):475-6 passim. (PMID: 4727126)
Physiol Behav. 2016 Dec 1;167:194-201. (PMID: 27654062)
J Physiol. 1956 Feb 28;131(2):452-62. (PMID: 13320346)
Eur J Clin Nutr. 2017 Oct;71(10):1154-1165. (PMID: 28098139)
Physiol Behav. 2023 Feb 1;259:114041. (PMID: 36427543)
Cell Mol Gastroenterol Hepatol. 2023;15(3):633-663. (PMID: 36410709)
Nutr Res. 2019 Mar;63:86-94. (PMID: 30824401)
معلومات مُعتمدة: NA This research was funded by the Coordination for the Improvement of Higher Education Per-sonnel (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES), CNPq, and Piauí Research Support Foundation (Fundação de Amparo à Pesquisa do Piauí - FA
فهرسة مساهمة: Keywords: appetite regulation; fatty acids; gastrointestinal motility; vagus nerve
المشرفين على المادة: 0 (Olive Oil)
0 (Neuropeptide Y)
5QUO05548Z (Palm Oil)
8001-22-7 (Soybean Oil)
8001-26-1 (Linseed Oil)
0 (Plant Oils)
66796-54-1 (Pro-Opiomelanocortin)
0 (Nerve Tissue Proteins)
0 (cocaine- and amphetamine-regulated transcript protein)
0 (RNA, Messenger)
تواريخ الأحداث: Date Created: 20240810 Date Completed: 20240810 Latest Revision: 20240812
رمز التحديث: 20240813
مُعرف محوري في PubMed: PMC11314563
DOI: 10.3390/nu16152397
PMID: 39125278
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu16152397