دورية أكاديمية

Altered states of consciousness in Danish healthy volunteers and recreational users of psilocybin and the possible impact of setting and intention: Danish validation of the five-dimensional altered states of consciousness questionnaire.

التفاصيل البيبلوغرافية
العنوان: Altered states of consciousness in Danish healthy volunteers and recreational users of psilocybin and the possible impact of setting and intention: Danish validation of the five-dimensional altered states of consciousness questionnaire.
المؤلفون: Hovmand OR; Psychiatric Research Unit, Region Zealand Psychiatry, Slagelse, Denmark.; Psychiatry South, Region Zealand Psychiatry, Vordingborg, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark., Madsen MK; Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Neurology, Odense University Hospital, Region of Southen Denmark, Denmark., Fisher PM; Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Stenbæk DS; Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Neurology, Odense University Hospital, Region of Southen Denmark, Denmark.; Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
المصدر: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2024 Aug 13, pp. 2698811241269669. Date of Electronic Publication: 2024 Aug 13.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Sage Publications Country of Publication: United States NLM ID: 8907828 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1461-7285 (Electronic) Linking ISSN: 02698811 NLM ISO Abbreviation: J Psychopharmacol Subsets: MEDLINE
أسماء مطبوعة: Publication: Thousand Oaks, CA : Sage Publications
Original Publication: Oxford, UK : Oxford University Press,
مستخلص: Background: Psychedelic substances reliably induce marked altered states of consciousness (ASC), which may be important for lasting effects and clinical outcomes of psychedelic intervention. Several instruments are available to measure the acute psychedelic experience, of which the Five Dimensional Altered States of Consciousness Questionnaire (5D-ASC) is commonly used. The questionnaire can be scored and analyzed as having five dimensions or 11 subscales, but the two have not been evaluated with comparable factor analysis methods.
Methods: The Danish translation of the 5D-ASC was completed by one sample of healthy volunteers receiving psilocybin in a laboratory setting ( N  = 47) and one sample of recreative users5D-ASC of psychedelics ( N  = 550), who reported retrospectively through an online survey based on their most recent experience with psilocybin. We calculated internal consistency measures of Cronbach's alpha and McDonald's omega, conducted a confirmatory factor analysis of the previously suggested factor structures, and tested for possible associations between the 5D-ASC total scores and dose, setting, and intention. For the 11 subscales, we reported omega-sem (composite reliability) using the parameters of the fitted confirmatory factor analyses model.
Results: Confirmatory factor analysis showed that the 11 subscales had a good fit to data and showed a better fit compared to the originally proposed five-dimensional solution and good internal consistencies. We further found that the 5D-ASC total scores correlated positively with the dose in the recreative sample. We found no correlations between 5D-ASC total scores and intention or setting.
Discussion: We find the Danish 5D-ASC to be a valid tool for measuring ASC among Danish-speaking individuals.
Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
فهرسة مساهمة: Keywords: Altered states of consciousness; LSD; psilocybin; psychedelics
تواريخ الأحداث: Date Created: 20240813 Latest Revision: 20240813
رمز التحديث: 20240813
DOI: 10.1177/02698811241269669
PMID: 39135498
قاعدة البيانات: MEDLINE
الوصف
تدمد:1461-7285
DOI:10.1177/02698811241269669