دورية أكاديمية

Long-term outcomes of ventricular tachycardia ablation in repaired tetralogy of Fallot: Systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Long-term outcomes of ventricular tachycardia ablation in repaired tetralogy of Fallot: Systematic review and meta-analysis.
المؤلفون: Prana Jagannatha GN; Faculty of Medicine Udayana University, Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia., Mendel B; Department of Cardiology and Vascular Medicine Sultan Sulaiman Government Hospital Serdang Bedagai North Sumatra Indonesia., Labi NPT; Faculty of Medicine Sam Ratulangi University Manado North Sulawesi Indonesia., Aji WC; Faculty of Medicine Muhammadiyah Yogyakarta University Yogyakarta Indonesia., Kosasih AM; Faculty of Medicine Udayana University, Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia., Adrian J; Faculty of Medicine Udayana University, Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia., de Liyis BG; Faculty of Medicine Udayana University, Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia., Pertiwi PFK; Faculty of Medicine Udayana University, Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia., Antara IMPS; Division of Electrophysiology and Cardiac Pacing, Department of Cardiology and Vascular Medicine, Faculty of Medicine Udayana University, Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.
المصدر: Journal of arrhythmia [J Arrhythm] 2024 Jun 12; Vol. 40 (4), pp. 935-947. Date of Electronic Publication: 2024 Jun 12 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: Japan NLM ID: 101263026 Publication Model: eCollection Cited Medium: Print ISSN: 1880-4276 (Print) Linking ISSN: 18804276 NLM ISO Abbreviation: J Arrhythm Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2018- : Tokyo : Wiley
Original Publication: Tokyo : Japanese Society of Cardiac Pacing and Electrophysiology
مستخلص: Background: Ventricular tachycardia (VT) remains a risk in repaired Tetralogy of Fallot (rTOF); however, long-term benefits of VT ablation have not been established. This study compares the outcomes of rTOF patients with and without VT ablation.
Methods: We searched multiple databases examining the outcomes of rTOF patients who had undergone VT ablation compared to those without ablation. Primary outcomes were VT recurrence, sudden cardiac death (SCD), and all-cause mortality. Subgroup analysis was conducted based on the type of ablation (catheter and surgical). Slow-conducting anatomical isthmus (SCAI)-based catheter ablation (CA) was also analyzed separately. The secondary outcome was the risk factors for the pre-ablation history of VT.
Results: Fifteen cohort studies with 1459 patients were included, 21.4% exhibited VTs. SCAI was found in 30.4% of the population, with 3.7% of non-inducible VT. Factors significantly associated with VT before ablation included a history of ventriculostomy, QRS duration ≥180 ms, fragmented QRS, moderate to severe pulmonary regurgitation, high premature ventricular contractions burden, late gadolinium enhancement, and SCAI. Ablation was only beneficial in reducing VTs recurrence in SCAI-based CA (risk ratio (RR) 0.11; 95% CI 0.03 to 0.33. p  < 0.001; I 2  = 0%) with no recurrence in patients with preventive ablation (mean follow-up time 91.14 ± 77.81 months). The outcomes of VT ablation indicated a favorable trend concerning SCD and all-cause mortality (RR 0.49 and 0.44, respectively); however, they were statistically insignificant.
Conclusions: SCAI-based CA has significant advantages in reducing VT recurrence in rTOF patients. Risk stratification plays a key role in determining the decision to perform ablation.
Competing Interests: The authors have no conflicts of interest to declare.
(© 2024 The Author(s). Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society.)
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فهرسة مساهمة: Keywords: ablation; slow‐conducting anatomical isthmus; sudden cardiac death; tetralogy of Fallot; ventricular tachycardia
تواريخ الأحداث: Date Created: 20240814 Latest Revision: 20240815
رمز التحديث: 20240815
مُعرف محوري في PubMed: PMC11317698
DOI: 10.1002/joa3.13095
PMID: 39139861
قاعدة البيانات: MEDLINE
الوصف
تدمد:1880-4276
DOI:10.1002/joa3.13095