دورية أكاديمية
أعرض في EDS

Effects of antiarrhythmic drug responsiveness and diagnosis-to-ablation time on outcomes after catheter ablation for persistent atrial fibrillation.

التفاصيل البيبلوغرافية
العنوان: Effects of antiarrhythmic drug responsiveness and diagnosis-to-ablation time on outcomes after catheter ablation for persistent atrial fibrillation.
المؤلفون: Kim HJ; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea.; Division of Cardiology, Department of Internal Medicine Yeungnam University College of Medicine Daegu Republic of Korea., Kim D; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea., Kim K; Yonsei University Health System Seoul Republic of Korea., Choi SH; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea.; Cardiology Division Gachon University Gil Medical Center Incheon Republic of Korea., Kim MH; Yonsei University Health System Seoul Republic of Korea., Park JW; Yonsei University Health System Seoul Republic of Korea., Yu HT; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea., Kim TH; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea., Uhm JS; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea., Joung B; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea., Lee MH; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea., Pak HN; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea.
المصدر: Journal of arrhythmia [J Arrhythm] 2024 Jul 02; Vol. 40 (4), pp. 867-878. Date of Electronic Publication: 2024 Jul 02 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: Japan NLM ID: 101263026 Publication Model: eCollection Cited Medium: Print ISSN: 1880-4276 (Print) Linking ISSN: 18804276 NLM ISO Abbreviation: J Arrhythm Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2018- : Tokyo : Wiley
Original Publication: Tokyo : Japanese Society of Cardiac Pacing and Electrophysiology
مستخلص: Background: The impact of delaying atrial fibrillation catheter ablation (AFCA) for antiarrhythmic drug (AAD) management on the disease course remains unclear. This study investigated AFCA rhythm outcomes based on the diagnosis-to-ablation time (DAT) and AAD responsiveness in participants with persistent AF (PeAF).
Methods: We included data from 1038 AAD-resistant PeAF participants, all of whom had a clear time point for AF diagnosis, especially PeAF at diagnosis time, and had undergone an AFCA for the first time. Participants who experienced recurrences of paroxysmal type on AAD therapy were analyzed as a cohort of AAD-partial responders; those maintaining PeAF on AAD were AAD-non-responders. We determined the DAT cutoff for best discriminating long-term rhythm outcomes using a maximum log-likelihood estimation method based on the Cox proportional hazard regression model.
Results: Of the participants (79.8% male; median age 61), 806 (77.6%) were AAD-non-responders. AAD-non-responders had a higher body mass index and a larger left atrial diameter than AAD-partial-responders. They also had a higher incidence of AF recurrence after AFCA (adjusted hazard ratio 1.75, 95% confidence interval 1.33-2.30; log-rank p  < .001) compared to AAD-partial-responders. The maximum log-likelihood estimation showed bimodal cutoffs at 22 and 40 months. The optimal DAT cutoff rhythm outcome was 22 months, which discriminated better in the AAD-partial-responders than in the AAD-non-responders.
Conclusions: Both DAT and AAD responsiveness influenced AFCA rhythm outcomes. Delaying AFCA to a DAT of longer than 22 months was inadvisable, particularly in the participants in whom PeAF was changed to paroxysmal AF during AAD therapy.
Competing Interests: Authors declare no conflict of interests for this article.
(© 2024 The Author(s). Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society.)
References: JAMA. 2023 Jan 10;329(2):127-135. (PMID: 36625809)
Eur Heart J. 2020 Jan 1;41(1):12-85. (PMID: 31820000)
J Cardiovasc Electrophysiol. 2011 Aug;22(8):839-45. (PMID: 21410581)
J Clin Pharm Ther. 2019 Oct;44(5):708-714. (PMID: 31056776)
Expert Rev Cardiovasc Ther. 2017 Apr;15(4):289-305. (PMID: 28267401)
JAMA. 2022 Jun 21;327(23):2296-2305. (PMID: 35727277)
BMJ. 2021 May 11;373:n991. (PMID: 33975876)
Circulation. 2019 Mar 5;139(10):e56-e528. (PMID: 30700139)
Heart Rhythm. 2017 Oct;14(10):e275-e444. (PMID: 28506916)
Eur Heart J. 2021 Feb 1;42(5):373-498. (PMID: 32860505)
N Engl J Med. 2023 Jan 12;388(2):105-116. (PMID: 36342178)
J Am Coll Cardiol. 2014 Jun 10;63(22):2335-45. (PMID: 24613319)
Am Heart J. 2012 May;163(5):887-93. (PMID: 22607868)
Circ Arrhythm Electrophysiol. 2020 Apr;13(4):e008128. (PMID: 32191539)
J Am Heart Assoc. 2013 Mar 18;2(2):e004549. (PMID: 23537812)
Eur Heart J. 2020 Dec 14;41(47):4483-4493. (PMID: 33022705)
Europace. 2012 May;14(5):646-52. (PMID: 22310154)
Heart Rhythm. 2012 Apr;9(4):632-696.e21. (PMID: 22386883)
Heart Rhythm. 2013 Sep;10(9):1257-62. (PMID: 23702238)
Nat Rev Cardiol. 2014 Nov;11(11):639-54. (PMID: 25113750)
Am J Cardiol. 2010 Jul 1;106(1):62-8. (PMID: 20609649)
Am J Cardiol. 2018 May 15;121(10):1192-1199. (PMID: 29571722)
Europace. 2018 Apr 1;20(4):589-595. (PMID: 28340103)
N Engl J Med. 2015 May 7;372(19):1812-22. (PMID: 25946280)
J Cardiovasc Electrophysiol. 2020 Feb;31(2):457-464. (PMID: 31919909)
Europace. 2023 Feb 16;25(2):351-359. (PMID: 36106534)
J Am Coll Cardiol. 2011 Jul 26;58(5):493-501. (PMID: 21777747)
Eur Heart J. 2023 Jul 14;44(27):2447-2454. (PMID: 37062010)
N Engl J Med. 2020 Oct 1;383(14):1305-1316. (PMID: 32865375)
Circ Res. 2020 Jun 19;127(1):4-20. (PMID: 32716709)
N Engl J Med. 2018 Feb 01;378(5):417-427. (PMID: 29385358)
J Am Coll Cardiol. 2022 Mar 15;79(10):951-961. (PMID: 35272799)
فهرسة مساهمة: Keywords: antiarrhythmic responsiveness; atrial fibrillation; atrial fibrillation catheter ablation; atrial fibrillation duration; clinical recurrence
تواريخ الأحداث: Date Created: 20240814 Latest Revision: 20240815
رمز التحديث: 20240815
مُعرف محوري في PubMed: PMC11317675
DOI: 10.1002/joa3.13104
PMID: 39139899
قاعدة البيانات: MEDLINE
الوصف
تدمد:1880-4276
DOI:10.1002/joa3.13104