دورية أكاديمية
أعرض في EDS

Hepatic resections for pediatric hepatoblastoma: analysis of 30-day outcomes using the National Surgical Quality Improvement Program-Pediatric database.

التفاصيل البيبلوغرافية
العنوان: Hepatic resections for pediatric hepatoblastoma: analysis of 30-day outcomes using the National Surgical Quality Improvement Program-Pediatric database.
المؤلفون: Thobani H; Section of Pediatric Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.; Division of Pediatric Surgery, Department of Surgery, Stanford Center for Academic Medicine, Lucile Packard Children's Hospital, 453 Quarry Rd, Palo Alto, Stanford, CA, 94304, USA., Durrani R; Section of Pediatric Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan., Raymond SL; Division of Pediatric Surgery, Department of Surgery, University of Florida, Gainesville, FL, USA., Shah AA; Department of Pediatric Surgery, Children's Hospital and Medical Center, University of Nebraska, Omaha, NE, USA., Islam S; Section of Pediatric Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan., Khan FA; Division of Pediatric Surgery, Department of Surgery, Stanford Center for Academic Medicine, Lucile Packard Children's Hospital, 453 Quarry Rd, Palo Alto, Stanford, CA, 94304, USA. fakhan1@stanford.edu.
المصدر: Pediatric surgery international [Pediatr Surg Int] 2024 Aug 17; Vol. 40 (1), pp. 230. Date of Electronic Publication: 2024 Aug 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8609169 Publication Model: Electronic Cited Medium: Internet ISSN: 1437-9813 (Electronic) Linking ISSN: 01790358 NLM ISO Abbreviation: Pediatr Surg Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin : Springer International, c1986-
مواضيع طبية MeSH: Hepatoblastoma*/surgery , Liver Neoplasms*/surgery , Hepatectomy*/methods , Quality Improvement* , Postoperative Complications*/epidemiology , Databases, Factual*, Humans ; Female ; Infant ; Male ; Child, Preschool ; Child ; Treatment Outcome ; Retrospective Studies ; Blood Transfusion/statistics & numerical data ; United States
مستخلص: Background: Surgical resection remains the cornerstone of treatment for hepatoblastoma in children and offers the best chance of disease-free survival. We aimed to analyze the 30 day outcomes of hepatic resection for hepatoblastoma stratified by extent using the National Surgical Quality Improvement Program-Pediatric (NSQIP-P).
Methods: We queried NSQIP-P for children undergoing resection of Hepatoblastoma from 2012 to 2021. Relevant clinical characteristics and outcomes were extracted for multivariate logistic regression to identify predictors of common adverse outcomes.
Results: We included 458 children with a median age of 1.90 years. Overall complications were rare, and perioperative blood transfusion (64.2%) and postoperative ventilation > 48 h (10.0%) were the only adverse events prevalent in more than 5% of patients. Median transfusion volume was 15.7 ml/kg. On multivariate regression, only patients undergoing Trisectionectomy (aOR = 3.387, 95% C.I. = 1.348-8.510) had higher odds of receiving > 75th percentile blood transfusion. Furthermore, only perioperative transfusion and postoperative ventilation > 48 h were statistically more common in patients undergoing extended versus standard resections.
Conclusions: Outcomes following resection of hepatoblastoma are excellent, with low rates of postoperative adverse events. Although children undergoing trisectionectomy likely require greater transfusion volume, extended hepatic resections do not appear to have worse 30 day outcomes despite greater operative complexity and duration.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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فهرسة مساهمة: Keywords: Children; Hepatectomy; Hepatic lobectomy; Hepatoblastoma; Pediatric liver tumors; Trisectionectomy
تواريخ الأحداث: Date Created: 20240817 Date Completed: 20240817 Latest Revision: 20240817
رمز التحديث: 20240818
DOI: 10.1007/s00383-024-05820-y
PMID: 39154089
قاعدة البيانات: MEDLINE
الوصف
تدمد:1437-9813
DOI:10.1007/s00383-024-05820-y