دورية أكاديمية
Comparison of two intravaginal progesterone-releasing devices in lactating Holstein cows synchronized with a 5-d GnRH-based timed-AI protocol.
| العنوان: | Comparison of two intravaginal progesterone-releasing devices in lactating Holstein cows synchronized with a 5-d GnRH-based timed-AI protocol. |
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| المؤلفون: | Colazo MG; Department of Agricultural Food and Nutritional Science, University of Alberta, Edmonton, T6G 2P5, Canada; Leduc Farm Animal Clinic, Leduc, T9E 6Z9, Canada. Electronic address: colazo@ualberta.ca., Behrouzi A; Department of Agricultural Food and Nutritional Science, University of Alberta, Edmonton, T6G 2P5, Canada., Gobikrushanth M; School of Veterinary Science, University of Queensland, Gatton, QLD, 4343, Australia. |
| المصدر: | Theriogenology [Theriogenology] 2024 Nov; Vol. 229, pp. 83-87. Date of Electronic Publication: 2024 Aug 14. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial, Veterinary; Comparative Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 0421510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3231 (Electronic) Linking ISSN: 0093691X NLM ISO Abbreviation: Theriogenology Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: [New York, N.Y.?] : Elsevier Original Publication: Los Altos, Calif., Geron-X. |
| مواضيع طبية MeSH: | Insemination, Artificial*/veterinary , Insemination, Artificial*/methods , Estrus Synchronization*/methods , Gonadotropin-Releasing Hormone*/pharmacology , Gonadotropin-Releasing Hormone*/administration & dosage , Progesterone*/administration & dosage , Progesterone*/pharmacology , Lactation*, Animals ; Cattle/physiology ; Female ; Pregnancy ; Administration, Intravaginal |
| مستخلص: | The objective of the study was to compare the effectiveness of CIDR vs. PRID-Delta devices for use in a 5-day Ovsynch protocol for TAI in lactating Holstein cows that were either not in estrus after the end of the voluntary waiting period or non-pregnant and not returning to estrus following the previous AI. Cows fitted with a collar-mounted automated activity monitoring system (Alta Cow Watch) were subjected to a standard 5-d Ovsynch protocol [100 μg of gonadorelin (GnRH) on Day 0 and 500 μg of cloprostenol on Days 5 and 6] and allocated randomly to receive either an intravaginal device containing 1.35 g (CIDR; n = 304) or 1.55 g (PRID ® DELTA; n = 304) of progesterone between Day 0 and 5. All cows received a second administration of GnRH at approximately 56 h and timed-AI (TAI) 72 h after intravaginal device removal. Inseminations were done using conventional frozen-thawed semen. Estrus events prior to TAI were recorded and transrectal ultrasonography was done on Day 0 to determine presence of a corpus luteum (CL) and 33 and 61 d post-TAI, respectively, to diagnose and confirm pregnancy. Cows had an average of 2.2 lactations, 124.3 days in milk, and a milk yield of 43.6 kg/d at enrollment. The overall percentage of cows with a CL at initiation of treatment was 68.8 % and did not differ between treatment groups. Cows with a CL had greater pregnancy per AI (P/AI) at 33 and 61 d post-TAI than cows without a CL (P < 0.01; 46.9 and 42.3 % vs. 32.1 and 27.4 %, respectively). The overall percentage of cows that expressed estrus prior to TAI was 24.8 % and did not differ between treatment groups; however, estrus expression prior to TAI affected P/AI at 33 and 61 d post-TAI (P < 0.01; 53.6 and 49.0 % vs. 38.5 and 33.9 % for those expressing or not expressing estrus, respectively). Pregnancy per AI at 33 d post-TAI tended to differ between treatment groups (P = 0.08; 46.1 vs. 38.5 % for PRID and CIDR groups, respectively) and P/AI at 61 d post-TAI was greater (P < 0.01) for PRID-treated cows (43.8 %) compared to CIDR-treated cows (31.6 %). Thus, PRID-treated cows had lower pregnancy loss than CIDR-treated cows (P < 0.01; 5.0 vs. 17.9 %). Also, treatment with a PRID tended (P = 0.08) to result in fewer twin pregnancies (7.9 vs. 14.5 % for PRID and CIDR treated cows, respectively). In conclusion, lactating dairy cows subjected to a 5-d Ovsynch TAI protocol plus a PRID-Delta had greater P/AI at 61 d post-TAI, lower pregnancy loss between 33 and 61 d post-TAI, and fewer twin pregnancies compared to cows subjected to a 5-d Ovsynch protocol plus a CIDR. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Cattle; Estrus: ovulation; Reproduction |
| المشرفين على المادة: | 33515-09-2 (Gonadotropin-Releasing Hormone) 4G7DS2Q64Y (Progesterone) |
| تواريخ الأحداث: | Date Created: 20240821 Date Completed: 20240908 Latest Revision: 20240908 |
| رمز التحديث: | 20240909 |
| DOI: | 10.1016/j.theriogenology.2024.08.018 |
| PMID: | 39167836 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-3231 |
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| DOI: | 10.1016/j.theriogenology.2024.08.018 |