دورية أكاديمية
أعرض في EDS

Influence of Depression on the Quality of Life in Patients With Parkinson's Disease in Southwest Nigeria.

التفاصيل البيبلوغرافية
العنوان: Influence of Depression on the Quality of Life in Patients With Parkinson's Disease in Southwest Nigeria.
المؤلفون: Orji OJ; Department of Acute Medicine, University Hospital of Derby and Burton, NHS Foundation Trust, Derby, GBR., Ijioma CE; Department of Pediatrics, Abia State Specialist Hospital and Diagnostics Centre, Umuahia, NGA., Odarah JE; Department of Geriatrics, JBS Gerontology Centre and Medicare Services, Lekki, NGA., Okeji IE; Department of General Medicine, North Cumbria Integrated Care, NHS Foundation Trust, North Cumbria, GBR., Areh JE; Department of Emergency Medicine, Warrington and Halton Hospitals, NHS Foundation Trust, Warrington, GBR., Anele DO; Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, Gregory University, Uturu, NGA.; Department of Neurology, Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Ogbomoso, NGA., Zacs IC; Department of Internal Medicine, Abia State University Teaching Hospital, Aba, NGA., Kalesanwo EA; Department of Surgery, Olabisi Onabanjo University Teaching Hospital, Sagamu, NGA., Austin-Jemifor O; Department of Internal Medicine, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham, NHS Foundation Trust, Birmingham, GBR., Nnamani UC; Department of General Practice, General Hospital, Umunze, NGA.
المصدر: Cureus [Cureus] 2024 Jul 22; Vol. 16 (7), pp. e65077. Date of Electronic Publication: 2024 Jul 22 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Background Parkinson's disease (PD) is a chronic neurodegenerative disorder that significantly impacts patients' quality of life (QoL). Depression is a common comorbidity in patients with PD, potentially exacerbating QoL deterioration. This study aimed to assess the influence of depression on QoL in patients with PD at Ladoke Akintola University of Technology (LAUTECH), Ogbomoso, Nigeria. Methodology A cross-sectional, descriptive study design was utilized. The study included 420 patients with PD attending the Neurology Clinic at LAUTECH. A purposive sampling technique was employed to select participants. Data collection instruments included the Unified Parkinson's Disease Rating Scale (UPDRS) for PD assessment, the Hoehn and Yahr scale for PD staging, the Patient Health Questionnaire-9 (PHQ-9) for depression evaluation, and the Parkinson's Disease Questionnaire-39 (PDQ-39) for QoL assessment. Data were analyzed using SPSS version 25.0 (IBM Corp., Armonk, NY), with descriptive and inferential statistics (Chi-square test) to determine associations, considering a P -value < 0.05 as significant. Results Among the participants, the prevalence of moderate to severe depression was 245, representing 58.81%. QoL assessment revealed that 297 (70.71%) patients with PD reported poor to very poor overall QoL. A significant association was found between the degree of depression and overall QoL ( P = 0.000). Patients with severe depression reported the poorest QoL, while those with minimal to no depression reported the highest QoL scores. Conclusions Depression significantly impacts the QoL in patients with PD at LAUTECH in southwest Nigeria. Addressing depression in PD management is crucial to improve patient outcomes.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Ethical Review Committee of Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Ogbomoso issued approval LTH/OGB/EC/2023/196. The study, reviewed by the Ethics Committee, was found to incorporate standard ethical considerations for public health research and posed no identifiable risks to the participants. It was considered valuable and beneficial for public health advancement and was hereby approved. . Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Orji et al.)
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فهرسة مساهمة: Keywords: depression; neurodegenerative disorder; parkinson's disease; quality of life; southwest
تواريخ الأحداث: Date Created: 20240822 Latest Revision: 20240823
رمز التحديث: 20240823
مُعرف محوري في PubMed: PMC11337142
DOI: 10.7759/cureus.65077
PMID: 39171038
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.65077