دورية أكاديمية
Anticancer, antimicrobial and antioxidant activity of CuO-ZnO bimetallic nanoparticles: green synthesised from Eryngium foetidum leaf extract.
العنوان: | Anticancer, antimicrobial and antioxidant activity of CuO-ZnO bimetallic nanoparticles: green synthesised from Eryngium foetidum leaf extract. |
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المؤلفون: | Daimari J; Department of Chemistry, Central Institute of Technology Kokrajhar (Deemed to be University, under MoE, Govt. of India), Kokrajhar, Assam, 783370, India., Deka AK; Department of Chemistry, Central Institute of Technology Kokrajhar (Deemed to be University, under MoE, Govt. of India), Kokrajhar, Assam, 783370, India. a.kalita@cit.ac.in. |
المصدر: | Scientific reports [Sci Rep] 2024 Aug 22; Vol. 14 (1), pp. 19506. Date of Electronic Publication: 2024 Aug 22. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: London : Nature Publishing Group, copyright 2011- |
مواضيع طبية MeSH: | Copper*/chemistry , Plant Extracts*/chemistry , Plant Extracts*/pharmacology , Zinc Oxide*/chemistry , Zinc Oxide*/pharmacology , Plant Leaves*/chemistry , Metal Nanoparticles*/chemistry , Antioxidants*/pharmacology , Antioxidants*/chemistry , Antioxidants*/chemical synthesis , Green Chemistry Technology* , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis, Humans ; MCF-7 Cells ; Anti-Infective Agents/pharmacology ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/chemical synthesis ; Microbial Sensitivity Tests ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry |
مستخلص: | In the present study, green synthetic pathway was adapted to synthesize CuO-ZnO bimetallic nanoparticles (BNPs) using Eryngium foetidum leaf extract and their anti-cancer activity against MCF7 breast cancer cell lines, anti-microbial activity and in vitro anti-oxidant activity were evaluated. Various bio-active compounds present in leaf extract were responsible for the reduction of CuO-ZnO NPs from respective Cu 2+ and Zn 2+ metal precursors. In the present study, the involvement of bio-active compounds present in E. foetidum extract before and after green synthesis of BNPs were evaluated for the first time. Rod-shaped and spherical structural morphology of synthesized BNPs were revealed by using FESEM, TEM, and XRD analysis with particle size ranged from 7 to 23 nm with an average size of 16.49 nm. The distribution of Cu and Zn were confirmed by elemental mapping. The green synthesized CuO-ZnO NPs showed significant cytotoxic effect with the inhibition rate 89.20 ± 0.03% at concentration of 500 μg/mL. Again, good antioxidant activity with IC (© 2024. The Author(s).) |
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معلومات مُعتمدة: | 202122-NFST-ASS-00285 UGC New Delhi India |
فهرسة مساهمة: | Keywords: E. foetidum; Anticancer; Antimicrobial; Antioxidant; BNPs; Green synthesis |
المشرفين على المادة: | 789U1901C5 (Copper) 0 (Plant Extracts) SOI2LOH54Z (Zinc Oxide) 0 (Antioxidants) V1XJQ704R4 (cupric oxide) 0 (Antineoplastic Agents) 0 (Anti-Infective Agents) 0 (Anti-Bacterial Agents) |
تواريخ الأحداث: | Date Created: 20240822 Date Completed: 20240822 Latest Revision: 20240822 |
رمز التحديث: | 20240823 |
DOI: | 10.1038/s41598-024-69847-w |
PMID: | 39174638 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2045-2322 |
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DOI: | 10.1038/s41598-024-69847-w |