دورية أكاديمية
أعرض في EDS

Association between C-reactive protein to albumin ratio and subclinical myocardial injury in the general population free from cardiovascular disease.

التفاصيل البيبلوغرافية
العنوان: Association between C-reactive protein to albumin ratio and subclinical myocardial injury in the general population free from cardiovascular disease.
المؤلفون: Li S; Department of Cardiology, Ningbo Ninth Hospital, No. 68 Xiangbei Road, Jiangbei District, Ningbo, 315000, Zhejiang, China., Wang Y; Department of Hyperbaric Oxygen, Rehabilitation Hospital Affiliated to National Research Center for Rehabilitation Technical Aids, Beijing, 100000, China., Xu N; Department of Cardiology, Ningbo Ninth Hospital, No. 68 Xiangbei Road, Jiangbei District, Ningbo, 315000, Zhejiang, China., Xie D; Department of Cardiology, Ningbo Ninth Hospital, No. 68 Xiangbei Road, Jiangbei District, Ningbo, 315000, Zhejiang, China. xdq1982@126.com.
المصدر: Journal of cardiothoracic surgery [J Cardiothorac Surg] 2024 Aug 23; Vol. 19 (1), pp. 487. Date of Electronic Publication: 2024 Aug 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101265113 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-8090 (Electronic) Linking ISSN: 17498090 NLM ISO Abbreviation: J Cardiothorac Surg Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, 2006-
مواضيع طبية MeSH: C-Reactive Protein*/analysis , C-Reactive Protein*/metabolism , Biomarkers*/blood , Nutrition Surveys*, Humans ; Male ; Female ; Middle Aged ; Myocardial Infarction/blood ; Myocardial Infarction/epidemiology ; Myocardial Infarction/diagnosis ; Adult ; Serum Albumin/analysis ; Aged ; Risk Factors ; United States/epidemiology ; Cross-Sectional Studies
مستخلص: Objective: The study aimed to examine the role of the C-reactive protein to albumin ratio (CAR) as an inflammatory biomarker in relation to subclinical myocardial injury (SC-MI), addressing the limited knowledge of their association.
Methods: The study included 5,949 individuals without cardiovascular disease (CVD) from the National Health and Nutrition Examination Survey. SC-MI was identified through a Cardiac Infarction Injury Score (CIIS) of ≥ 10 units based on a 12-lead electrocardiogram. The study used multivariate logistic regression models, adjusted for potential confounders, to evaluate the relationship between CAR and SC-MI. Subgroup analyses were conducted to substantiate the results, and the non-linear correlation was assessed via restricted cubic spline (RCS) regression.
Results: The RCS curve showed a significant positive correlation between CAR and SC-MI (P for nonlinear = 0.2496). When adjusted for all confounders, individuals in the highest tertile of CAR exhibited a higher likelihood of SC-MI compared to those in the lowest tertile, with an odds ratio (OR) of 1.21 (95% CI: 1.06-1.39, P for trend = 0.029). A 10-unit increment in CAR was linked to a 3.6% heightened risk of SC-MI [OR = 1.036 (95% CI: 1.006, 1.066)], with this association being more prominent among male adults, non-smokers, married individuals, those without diabetes mellitus, and those with no history of cancer.
Conclusion: The findings of this study suggest a positive correlation between CAR and SC-MI among the US adult population, indicating the potential of CAR in enhancing SC-MI prevention strategies in the general population.
(© 2024. The Author(s).)
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معلومات مُعتمدة: 2021C02 Jiangbei District Science and Technology Programme
فهرسة مساهمة: Keywords: Albumin; C-reactive protein; Cardiovascular disease; Subclinical myocardial injury
المشرفين على المادة: 9007-41-4 (C-Reactive Protein)
0 (Biomarkers)
0 (Serum Albumin)
تواريخ الأحداث: Date Created: 20240822 Date Completed: 20240823 Latest Revision: 20240822
رمز التحديث: 20240823
DOI: 10.1186/s13019-024-02988-1
PMID: 39175007
قاعدة البيانات: MEDLINE
الوصف
تدمد:1749-8090
DOI:10.1186/s13019-024-02988-1