دورية أكاديمية
أعرض في EDS

Impact of moderate-to-high-suicide-intent in major depressive disorder: a retrospective cohort study on patient characteristics and healthcare resource utilisation in England.

التفاصيل البيبلوغرافية
العنوان: Impact of moderate-to-high-suicide-intent in major depressive disorder: a retrospective cohort study on patient characteristics and healthcare resource utilisation in England.
المؤلفون: Denee T; Janssen-Cilag Ltd, 50-100 Holmers Farm Way, High Wycombe, Buckinghamshire, HP12 4EG, UK. tdenee@its.jnj.com., Kerr C; Janssen-Cilag Ltd, 50-100 Holmers Farm Way, High Wycombe, Buckinghamshire, HP12 4EG, UK., Richards S; Janssen-Cilag Ltd, 50-100 Holmers Farm Way, High Wycombe, Buckinghamshire, HP12 4EG, UK., Dennis N; Amaris Health Economics and Market Access, 7 Rue de Châteaudun, Paris, 75009, France., Foix-Colonier A; Amaris Health Economics and Market Access, 7 Rue de Châteaudun, Paris, 75009, France., Fischer C; Amaris Health Economics and Market Access, 7 Rue de Châteaudun, Paris, 75009, France., Larkin F; Acute Mental Health Services, West London NHS Trust, London, UK.
المصدر: BMC psychiatry [BMC Psychiatry] 2024 Aug 23; Vol. 24 (1), pp. 576. Date of Electronic Publication: 2024 Aug 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968559 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-244X (Electronic) Linking ISSN: 1471244X NLM ISO Abbreviation: BMC Psychiatry Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Depressive Disorder, Major*/epidemiology , Patient Acceptance of Health Care*/statistics & numerical data, Humans ; Female ; Male ; Adult ; England ; Retrospective Studies ; Middle Aged ; Mental Health Services/statistics & numerical data ; Suicide, Attempted/statistics & numerical data ; Young Adult ; Primary Health Care/statistics & numerical data ; Adolescent ; Aged ; Hospitalization/statistics & numerical data ; Suicidal Ideation
مستخلص: Background: Major depressive disorder (MDD) is a disabling mental illness that can affect all aspects of daily life and is a leading cause of healthcare resource utilisation (HCRU).
Aims: We aimed to characterise patients with MDD with moderate-to-high-suicide-intent, compare their HCRU to patients with MDD without moderate-to-high-suicide-intent, and better understand their patient pathways.
Methods: This retrospective cohort study used data collected from primary care electronic health records from Clinical Practice Research Datalink (CPRD), linked to Hospital Episode Statistics, Mental Health Services Data Set, and Office for National Statistics in England. Adults diagnosed with ≥ 1 MDD diagnosis between 04/2007 and 11/2015 were categorised by suicide intent.
Results: 307,476 patients with MDD were included (294,259 patients without moderate-to-high-suicide-intent and 13,217 with moderate-to-high-suicide-intent). Patients with MDD with moderate-to-high-suicide-intent were younger on average (39.0 vs. 44.8 years) and included a lower percentage of females (58% vs. 65%) compared to patients without moderate-to-high-suicide-intent. HCRU was greater among patients with moderate-to-high-suicide-intent than patients without moderate-to-high-suicide-intent during the first follow-up year for general practitioner consultations (38.5 vs. 29.4), psychiatric outpatient visits (1.5 vs. 0.1), psychiatrist visits (3.6 vs. 0.3), emergency visits (1.5 vs. 0.3), and hospitalisations (86% vs. 26%). Overall, 56% of patients with moderate-to-high-suicide-intent had an antidepressant prescription within 30 days from the initial moderate-to-high-suicide-intent.
Conclusions: Patients with MDD and moderate-to-high-suicide-intent were younger, included more males and incurred greater HCRU than those without moderate-to-high-suicide-intent. These results suggest a greater need for effective medical care and appropriate treatments for patients with moderate-to-high-suicide-intent, which could help reduce associated symptoms, mortality, and HCRU.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Clinical practice research datalink (CPRD); England; Healthcare Resource use; Hospital episode statistics (HES); Major depressive disorder; Mental health services data set (MHSDS); Office for National statistics (ONS); Population-based study; Suicide intent
تواريخ الأحداث: Date Created: 20240823 Date Completed: 20240824 Latest Revision: 20240826
رمز التحديث: 20240826
مُعرف محوري في PubMed: PMC11342576
DOI: 10.1186/s12888-024-05961-3
PMID: 39180055
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-244X
DOI:10.1186/s12888-024-05961-3