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Symptoms of Depression, Eating Disorders, and Binge Eating in Adolescents With Obesity: The Fast Track to Health Randomized Clinical Trial.

التفاصيل البيبلوغرافية
العنوان: Symptoms of Depression, Eating Disorders, and Binge Eating in Adolescents With Obesity: The Fast Track to Health Randomized Clinical Trial.
المؤلفون: Jebeile H; The University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.; The Children's Hospital at Westmead, Institute of Endocrinology and Diabetes, Westmead, New South Wales, Australia., Baur LA; The University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.; The Children's Hospital at Westmead, Weight Management Services, Westmead, New South Wales, Australia., Kwok C; The University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.; The Children's Hospital at Westmead, Weight Management Services, Westmead, New South Wales, Australia., Alexander S; The Children's Hospital at Westmead, Weight Management Services, Westmead, New South Wales, Australia., Brown J; Monash Children's Hospital, Department of Paediatric Endocrinology and Diabetes, Clayton, Victoria, Australia.; Monash University, Department of Paediatrics, Clayton, Victoria, Australia., Collins CE; University of Newcastle, School of Health Sciences, College of Health, Medicine and Wellbeing, Callaghan, New South Wales, Australia.; Food and Nutrition Research Program, Hunter Medical research Institute, New Lambton Heights, New South Wales, Australia., Cowell CT; The University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.; Kids Research, The Children's Hospital at Westmead, Westmead, New South Wales, Australia., Day K; Monash University, Nutrition, Dietetics & Food, Melbourne, Victoria, Australia.; School of Agriculture, Food and Ecosystem Sciences, University of Melbourne, Melbourne, Victoria, Australia., Garnett SP; The University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.; Kids Research, The Children's Hospital at Westmead, Westmead, New South Wales, Australia., Gow ML; The University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia., Grunseit AM; The Children's Hospital at Westmead, Nutrition and Dietetics, Westmead, New South Wales, Australia., Henderson M; The Children's Hospital at Westmead, Institute of Endocrinology and Diabetes, Westmead, New South Wales, Australia., House ET; The University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.; The Children's Hospital at Westmead, Institute of Endocrinology and Diabetes, Westmead, New South Wales, Australia., Inkster MK; Monash Children's Hospital, Department of Paediatric Endocrinology and Diabetes, Clayton, Victoria, Australia.; Monash University, Nutrition, Dietetics & Food, Melbourne, Victoria, Australia., Lang S; Monash University, Nutrition, Dietetics & Food, Melbourne, Victoria, Australia., Paxton SJ; La Trobe University, School of Psychology and Public Health, Melbourne, Victoria, Australia., Truby H; School of Primary and Allied Health Care, Monash University, Melbourne, Victoria, Australia.; School of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, Queensland, Australia., Varady KA; University of Illinois, Department of Kinesiology and Nutrition, Chicago., Lister NB; The University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.; The Children's Hospital at Westmead, Institute of Endocrinology and Diabetes, Westmead, New South Wales, Australia.
المصدر: JAMA pediatrics [JAMA Pediatr] 2024 Aug 26. Date of Electronic Publication: 2024 Aug 26.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2168-6211 (Electronic) Linking ISSN: 21686203 NLM ISO Abbreviation: JAMA Pediatr Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Chicago, IL : American Medical Association, [2013]-
مستخلص: Importance: Depression and eating disorders are heightened for adolescents with obesity. Clinical reviews alongside self-report questionnaires are important to ensure appropriate intervention.
Objective: To evaluate changes in self-report symptoms of depression, eating disorders, and binge eating in adolescents with obesity during the Fast Track to Health trial.
Design, Setting, and Participants: This was a randomized clinical trial conducted from 2018 to 2023. It was a multisite trial conducted at children's hospitals in Sydney, New South Wales, and Melbourne, Victoria, Australia, and included adolescents (13-17 years) with obesity (defined as adult equivalent body mass index ≥30; calculated as weight in kilograms divided by height in meters squared) and 1 or more related complications.
Interventions: Duration was 52 weeks including a very low energy diet for 4 weeks followed by intermittent energy restriction (IER) or continuous energy restriction (CER).
Main Outcomes and Measures: Self-report symptoms of depression (Center for Epidemiologic Studies Depression Scale-Revised 10-Item Version for Adolescents [CESDR-10]; scores 0-30), eating disorders (Eating Disorder Examination Questionnaire [EDE-Q]; scores 0-6), and binge eating (Binge Eating Scale [BES]; scores 0-46) were assessed. Adolescents were screened for depression and eating disorders (weeks 0, 4, 16, and 52) and monitored for the onset of new symptoms of disordered eating during dietetic consults.
Results: Of 141 adolescents (median [IQR] age, 14.8 [12.9-17.9] years; 71 male [50.4%]) enrolled, median baseline EDE-Q score was 2.28 (IQR, 1.43-3.14), median baseline CESDR-10 score was 9.00 (IQR, 4.00-14.50), and median baseline BES score was 11.00 (IQR, 5.00-17.00). There were no differences between groups for change in CESDR-10 (mean difference at week 52, 0.75; 95% CI, -1.86 to 3.37), EDE-Q (mean difference at week 52, 0.02; 95% CI, -0.41 to 0.45), or BES (mean difference at week 52, -2.91; 95% CI, -5.87 to 0.05). The within-group reductions at week 4 were maintained at week 52, for CESDR-10 and EDE-Q, indicating reduced symptoms of depression and eating disorders. Within-group reductions on the BES were maintained in the IER group only. Seventeen adolescents (12.1%) required support or referral for depression and/or disordered eating, including 7 (5%; 5 IER, 2 CER) adolescents who experienced the onset or reemergence of symptoms during the intervention.
Conclusions and Relevance: Results suggest that many treatment-seeking adolescents with obesity self-reported symptoms of depression and eating disorders. Although symptoms reduced for most, some required additional support. Obesity treatment is an opportune time to screen and monitor for depression and disordered eating.
Trial Registration: Australian New Zealand Clinical Trials Registry: ACTRN12617001630303.
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تواريخ الأحداث: Date Created: 20240826 Latest Revision: 20240829
رمز التحديث: 20240830
مُعرف محوري في PubMed: PMC11348093
DOI: 10.1001/jamapediatrics.2024.2851
PMID: 39186289
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-6211
DOI:10.1001/jamapediatrics.2024.2851