دورية أكاديمية
Prognostic Value of Resting Left Ventricular Sphericity Indexes in Coronary Artery Disease With Preserved Ejection Fraction.
| العنوان: | Prognostic Value of Resting Left Ventricular Sphericity Indexes in Coronary Artery Disease With Preserved Ejection Fraction. |
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| المؤلفون: | Wu P; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University Taiyuan China., Zhao Y; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China., Guo X; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University Taiyuan China., Liu X; Department of Radiology Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University Taiyuan China., Hu Y; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Shanxi Key Laboratory of Molecular Imaging Shanxi Medical University Taiyuan Shanxi China., Xiao Y; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Shanxi Key Laboratory of Molecular Imaging Shanxi Medical University Taiyuan Shanxi China., Xu L; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Shanxi Key Laboratory of Molecular Imaging Shanxi Medical University Taiyuan Shanxi China., Huang N; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China., Li Y; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Shanxi Key Laboratory of Molecular Imaging Shanxi Medical University Taiyuan Shanxi China., Wang Y; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Shanxi Key Laboratory of Molecular Imaging Shanxi Medical University Taiyuan Shanxi China., Ren T; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Shanxi Key Laboratory of Molecular Imaging Shanxi Medical University Taiyuan Shanxi China., Wu Q; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Shanxi Key Laboratory of Molecular Imaging Shanxi Medical University Taiyuan Shanxi China., Wang R; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Shanxi Key Laboratory of Molecular Imaging Shanxi Medical University Taiyuan Shanxi China., Zhang X; Laboratory for Molecular Imaging, Department of Nuclear Medicine Beijing Anzhen Hospital, Capital Medical University Beijing China., Wu Z; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University Taiyuan China., Li S; Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan China.; Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University Taiyuan China. |
| المصدر: | Journal of the American Heart Association [J Am Heart Assoc] 2024 Sep 03; Vol. 13 (17), pp. e032169. Date of Electronic Publication: 2024 Aug 27. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford : Wiley-Blackwell |
| مواضيع طبية MeSH: | Coronary Artery Disease*/physiopathology , Coronary Artery Disease*/diagnosis , Coronary Artery Disease*/diagnostic imaging , Stroke Volume*/physiology , Myocardial Perfusion Imaging*/methods , Ventricular Function, Left*/physiology, Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Prognosis ; Aged ; Ventricular Remodeling/physiology ; Predictive Value of Tests ; Heart Ventricles/physiopathology ; Heart Ventricles/diagnostic imaging |
| مستخلص: | Background: Adverse left ventricular remodeling is a significant cardiovascular predictor for patients with coronary artery disease and preserved left ventricular ejection fraction (LVEF). However, the remodeling indexes reflecting left ventricular spherization by myocardial perfusion imaging are underexplored. Methods and Results: 727 patients (mean age 59.8±13.5 years, 329 women) diagnosed or suspected coronary artery disease with preserved LVEF who underwent resting myocardial perfusion imaging were retrospectively enrolled. The myocardial perfusion imaging findings including the total perfusion deficit and sphericity indexes (shape index (SI) and eccentricity index (EI) obtained from gated (QGS) and non-gated (QPS) images) were collected. Major adverse cardiovascular events (MACE) were followed up for 45.1±22.0 months. All patients were divided into 4 subgroups based on total perfusion deficit at 10% and LVEF at 65%. Univariable comparative analyses were performed in 5 cohorts (all patients and 4 subgroups). Patients who experienced MACE displayed higher SI and/or lower EI (all P <0.05). Kaplan-Meier survival analyses suggested significant differences for SI Conclusions: For patients diagnosed or suspected of coronary artery disease with preserved or supra-normal LVEF, resting sphericity indexes by myocardial perfusion imaging displayed incremental long-term prognostic value. Among these indicators, SI |
| فهرسة مساهمة: | Keywords: myocardial ischemia; myocardial perfusion imaging; preserved left ventricular ejection fraction; sphericity indexes; prognosis |
| تواريخ الأحداث: | Date Created: 20240827 Date Completed: 20240903 Latest Revision: 20240903 |
| رمز التحديث: | 20240903 |
| DOI: | 10.1161/JAHA.123.032169 |
| PMID: | 39189479 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2047-9980 |
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| DOI: | 10.1161/JAHA.123.032169 |