دورية أكاديمية
Effect of aerobic exercise program on neuropathic pain and quality of life in person with paraplegia: study protocol for a randomized controlled trial.
| العنوان: | Effect of aerobic exercise program on neuropathic pain and quality of life in person with paraplegia: study protocol for a randomized controlled trial. |
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| المؤلفون: | Gera A; Indian Spinal Injuries Centre, Institute of Rehabilitation Sciences, Guru Gobind Singh Indraprastha University, New Delhi, India., Walia S; Indian Spinal Injuries Centre, Institute of Rehabilitation Sciences, Guru Gobind Singh Indraprastha University, New Delhi, India. shef0604@gmail.com.; Department of Physiotherapy, Gurugram University, GURGAON, India. shef0604@gmail.com., Khanna S; Indian Spinal Injuries Centre, Institute of Rehabilitation Sciences, Guru Gobind Singh Indraprastha University, New Delhi, India., Wadhwa G; Indian Spinal Injuries Centre, Institute of Rehabilitation Sciences, Guru Gobind Singh Indraprastha University, New Delhi, India. |
| المصدر: | Trials [Trials] 2024 Sep 02; Vol. 25 (1), pp. 580. Date of Electronic Publication: 2024 Sep 02. |
| نوع المنشور: | Journal Article; Clinical Trial Protocol |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [London] : BioMed Central, 2006- |
| مواضيع طبية MeSH: | Quality of Life* , Neuralgia*/therapy , Neuralgia*/physiopathology , Neuralgia*/psychology , Paraplegia*/rehabilitation , Paraplegia*/physiopathology , Paraplegia*/psychology , Exercise Therapy*/methods , Randomized Controlled Trials as Topic* , Spinal Cord Injuries*/complications , Spinal Cord Injuries*/rehabilitation , Spinal Cord Injuries*/physiopathology , Spinal Cord Injuries*/psychology, Humans ; Double-Blind Method ; Adult ; Middle Aged ; Treatment Outcome ; Male ; Female ; Exercise ; Pain Measurement ; Time Factors ; Young Adult |
| مستخلص: | Background: Individuals with spinal cord injury (SCI) often suffer from neuropathic pain which is often disabling and negatively affects function, participation, and quality of life (QoL). Pharmacological treatments lack efficacy in neuropathic pain reduction hence studying alternatives to drug treatment is necessary. Preclinical evidence of various aerobic exercises has shown positive effects on neuropathic pain but scientific studies investigating its effect in the SCI human population are limited. Methodology: This study is a double-blind, parallel, two-group, randomized controlled trial with an interventional study design that aims to evaluate the effectiveness of aerobic exercise program on neuropathic pain and quality of life (QoL) in individuals with chronic paraplegia. Thirty individuals with chronic paraplegia with the neurological level of injury from T2 to L2 will be recruited from the rehabilitation department at a super specialty hospital based on the inclusion criteria. Using a 1:1 allocation ratio, the participants will be randomly assigned to one of the two groups. The intervention group will perform high-intensity interval training (HIIT) aerobic exercise using an arm ergometer based on their peak heart rate, and the control group will perform free-hand arm aerobic exercise. In both groups, the intervention will be delivered as 30-min sessions, four times a week for 6 weeks. Outcome Measures: International Spinal Cord Injury Pain Basic Data Set Version 3.0 will be used for diagnosing and assessing neuropathic pain and its interference with day-to-day activities, mood, and sleep. The International Spinal Cord Society (ISCoS) QoL basic data set will be used to assess QoL, and 6-min push test distance will be used to assess peak heart rate and aerobic capacity. Discussion: The effectiveness of the aerobic exercise program will be assessed based on the changes in neuropathic pain score and its interference with day-to-day activities, mood, sleep, QoL, and aerobic capacity after 3 weeks mid-intervention and after 6 weeks post-intervention. The trial will provide new knowledge about the effectiveness of the aerobic exercise program in improving neuropathic pain and QoL in individuals with chronic paraplegia. Trial Registration: Clinical Trials Registry-India CTRI/2023/08/056257. Registered on 8 August 2023. (© 2024. The Author(s).) |
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| فهرسة مساهمة: | Keywords: Aerobic exercise; High-intensity interval training; Neuropathic pain; Paraplegia; Randomized controlled trial |
| تواريخ الأحداث: | Date Created: 20240902 Date Completed: 20240903 Latest Revision: 20240905 |
| رمز التحديث: | 20240905 |
| مُعرف محوري في PubMed: | PMC11370080 |
| DOI: | 10.1186/s13063-024-08430-0 |
| PMID: | 39223575 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1745-6215 |
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| DOI: | 10.1186/s13063-024-08430-0 |