دورية أكاديمية
أعرض في EDS

MRI-based assessment paraspinal extensor muscle fatty infiltration in acute cervical spinal cord injury patients - a retrospective study.

التفاصيل البيبلوغرافية
العنوان: MRI-based assessment paraspinal extensor muscle fatty infiltration in acute cervical spinal cord injury patients - a retrospective study.
المؤلفون: Liao Y; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China., Lin X; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China., Su W; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China., Wu X; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China., Wang X; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China., Yang W; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China., Lu H; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China., Huang C; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China., Wu Y; Department of Spinal Surgery, Longyan First Hospital (Longyan First Affiliated Hospital of Fujian Medical University), Longyan, 364000, China. wuyiqi1983@163.com.
المصدر: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2024 Sep 03; Vol. 25 (1), pp. 702. Date of Electronic Publication: 2024 Sep 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474 (Electronic) Linking ISSN: 14712474 NLM ISO Abbreviation: BMC Musculoskelet Disord Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2000-
مواضيع طبية MeSH: Spinal Cord Injuries*/diagnostic imaging , Spinal Cord Injuries*/pathology , Paraspinal Muscles*/diagnostic imaging , Paraspinal Muscles*/pathology , Magnetic Resonance Imaging* , Cervical Vertebrae*/diagnostic imaging , Cervical Vertebrae*/pathology , Adipose Tissue*/diagnostic imaging , Adipose Tissue*/pathology, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Aged ; Adult ; Case-Control Studies
مستخلص: Background: The effect of fat infiltration in the paraspinal muscles on cervical degenerative disease has been confirmed by multiple studies. However, little is known about fat infiltration in the paraspinal extensors in patients with acute cervical spinal cord injury (SCI). This study aimed to investigate the difference in paraspinal extensor fatty infiltration between patients with acute cervical SCI and healthy controls, and to further explore the protective role of the paravertebral extensor muscles in patients with cervical SCI.
Methods: A total of 50 patients with acute cervical SCI admitted to the emergency department from January 2019 to November 2023 were retrospectively analyzed, including 26 males and 24 females, with an average age of 59.60 ± 10.81 years. A control group of 50 healthy middle-aged and elderly individuals was also included, comprising 28 males and 22 females, with an average age of 55.00 ± 8.21 years. Cervical spine magnetic resonance imaging (MRI) was used to measure the cross-sectional areas of the superficial and deep cervical extensor muscles, the corresponding vertebral body cross-sectional areas, and the fat area within the superficial and deep extensor muscle groups using Image J software. Differences between the two groups were compared, and the cervical SCI patients were further analyzed based on the severity of the spinal cord injury and gender differences.
Results: The deep fatty infiltration ratio (DFIR) and superficial fatty infiltration ratio (SFIR) at C4-C7 in the cervical SCI group were significantly higher than those in the control group (P < 0.001). The cross-sectional area of the functional deep extensor area (FDEA) relative to the vertebral body area (VBA) and the cross-sectional area of the functional superficial extensor area (FSEA) relative to the VBA at the C5 and C6 levels in the cervical SCI group were significantly lower than those in the control group (P < 0.001, P < 0.001, P = 0.034, P = 0.004 respectively). Among the cervical SCI patients, the cross-sectional areas of the deep extensor area (DEA) and the superficial extensor area (SEA) in males were significantly higher than those in females (P < 0.001). At the C6 and C7 levels, the FDEA/VBA and FSEA/VBA ratios in the male group were higher than those in the female group (P = 0.009, P = 0.022, P = 0.019, P = 0.005, respectively).
Conclusion: Patients with acute cervical SCI exhibit significantly higher fatty infiltration and a greater degree of paravertebral extensor muscle degeneration compared to healthy controls. This finding underscores the importance of the paravertebral extensor muscles in the context of cervical SCI and may guide future therapeutic strategies.
(© 2024. The Author(s).)
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معلومات مُعتمدة: 2021LYF17022 Longyan Science and Technology Project; 2021LYF17022 Longyan Science and Technology Project; 2021LYF17022 Longyan Science and Technology Project; 2021LYF17022 Longyan Science and Technology Project; 2021LYF17022 Longyan Science and Technology Project; 2021LYF17022 Longyan Science and Technology Project
فهرسة مساهمة: Keywords: Cervical; Cervical extensor; Cross-sectional; Fat infiltration; Magnetic resonance imaging; Paraspinal muscle; Spinal cord injuries; Spine
تواريخ الأحداث: Date Created: 20240903 Date Completed: 20240904 Latest Revision: 20240906
رمز التحديث: 20240906
مُعرف محوري في PubMed: PMC11370304
DOI: 10.1186/s12891-024-07808-0
PMID: 39227803
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2474
DOI:10.1186/s12891-024-07808-0