Uptake and Persistence of Safer Conception Strategies Among South African Women Planning for Pregnancy.

التفاصيل البيبلوغرافية
العنوان:	Uptake and Persistence of Safer Conception Strategies Among South African Women Planning for Pregnancy.
المؤلفون:	Isehunwa OO; Division of Infectious Diseases, Heersink School of Medicine, University of Alabama at Birmingham, 703 19Th Street South, Birmingham, AL, 35233, USA. oluwaseyiisehunwa@uabmc.edu., Jaggernath M; Wits MRU (MatCH Research Unit), Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa., Kriel Y; Wits MRU (MatCH Research Unit), Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa., Psaros C; Department of Psychiatry, Massachusetts General Hospital, Boston, USA.; Department of Medicine, Harvard Medical School, Boston, USA., Mathenjwa M; Epidemiology and Prevention Department, Centre for the AIDS Programme of South Africa (CAPRISA), Durban, South Africa., Hurwitz KE; Target RWE, Durham, NC, USA., Bennett K; Target RWE, Durham, NC, USA., Smith PM; Division of Infectious Diseases, Heersink School of Medicine, University of Alabama at Birmingham, 703 19Th Street South, Birmingham, AL, 35233, USA., Bangsberg DR; Vin University College of Health Sciences, Hanoi, Vietnam., Marrazzo JM; Division of Infectious Diseases, Heersink School of Medicine, University of Alabama at Birmingham, 703 19Th Street South, Birmingham, AL, 35233, USA., Haberer JE; Department of Medicine, Harvard Medical School, Boston, USA.; Center for Global Health, Massachusetts General Hospital, Boston, USA., Smit JA; Wits MRU (MatCH Research Unit), Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa., Matthews LT; Division of Infectious Diseases, Heersink School of Medicine, University of Alabama at Birmingham, 703 19Th Street South, Birmingham, AL, 35233, USA.
المصدر:	AIDS and behavior [AIDS Behav] 2024 Sep 06. Date of Electronic Publication: 2024 Sep 06.
Publication Model:	Ahead of Print
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9712133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-3254 (Electronic) Linking ISSN: 10907165 NLM ISO Abbreviation: AIDS Behav Subsets: MEDLINE
أسماء مطبوعة:	Publication: 2005- : New York, NY : Springer Science + Business Media Original Publication: New York, NY : Plenum Press, 1997-
مستخلص:	Safer conception strategies can minimize HIV acquisition during periconception periods among women living in HIV-endemic areas. We examined uptake and predictors of persistent use of the same safer conception strategy among a cohort of HIV-uninfected South African women ages 18-35 years planning for pregnancy with a partner living with HIV or of unknown HIV-serostatus. The safer conception strategies we evaluated included oral PrEP, condomless sex limited to peak fertility, and waiting for a better time to have a child (until, for example, the risks of HIV acquisition are reduced and/or the individual is prepared to care for a child); persistence was defined as using the same safer conception strategy from the first visit through 9 months follow-up. Modified Poisson regression models were used to examine predictors of persistent use of the same strategy. The average age of 227 women in our cohort was 24.6 (range: 18.0, 35.7) years. In this cohort, 121 (74.2%) women reported persisting in the same strategy through 9 months. Employment and HIV knowledge were associated with the persistent use of any strategy. Our results highlight the need to provide safer conception services to women exposed to HIV during periconception periods. Findings also offer some insights into factors that might influence persistent use. Further research is needed to better understand how to involve male partners and how their involvement might influence women's consistent use of safer conception strategies during periconception periods. (© 2024. The Author(s).)
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معلومات مُعتمدة:	NIMHK23MH095655 Natonal institute of health; NIMHR01MH108412 National Institute of Health
فهرسة مساهمة:	Keywords: HIV prevention; Persistence; Safer conception strategies; South Africa; Women planning for pregnancy
تواريخ الأحداث:	Date Created: 20240906 Latest Revision: 20240906
رمز التحديث:	20240906
DOI:	10.1007/s10461-024-04475-z
PMID:	39240299
قاعدة البيانات:	MEDLINE

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تدمد:	1573-3254
DOI:	10.1007/s10461-024-04475-z