دورية أكاديمية
Management dilemma: managing bipolar affective disorder in a patient with hereditary angioedema.
| العنوان: | Management dilemma: managing bipolar affective disorder in a patient with hereditary angioedema. |
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| المؤلفون: | Wimalasiri IU; Mental Health and Wellbeing Services, Western Health, Sunshine, Victoria, Australia isuri.wimalasiri@wh.org.au.; Faculty of Medicine, General Sir John Kotelawala Defence University, Ratmalana, Sri Lanka., Jain N; Mental Health and Wellbeing Services, Western Health, Sunshine, Victoria, Australia.; Department of Psychiatry, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne , Melbourne, Victoria, Australia., Jayaram M; Mental Health and Wellbeing Services, Western Health, Sunshine, Victoria, Australia.; Department of Psychiatry, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne , Melbourne, Victoria, Australia. |
| المصدر: | BMJ case reports [BMJ Case Rep] 2024 Sep 17; Vol. 17 (9). Date of Electronic Publication: 2024 Sep 17. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BMJ Pub. Group |
| مواضيع طبية MeSH: | Bipolar Disorder*/complications , Bipolar Disorder*/drug therapy , Angioedemas, Hereditary*/complications , Angioedemas, Hereditary*/drug therapy, Humans ; Female ; Middle Aged ; Suicidal Ideation |
| مستخلص: | Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by the deficiency or dysfunction of C1 esterase inhibitors. We present a case of a female in her 50s with HAE and bipolar affective disorder (BPAD). She has experienced severe depressive and manic episodes with significant disruption to her life. She has also had potentially life-threatening episodes of recurrent angioedema with severe facial and body swelling and post-pharyngeal symptoms.She presented to us with a depressive episode with suicidal ideation. Her angioedema was flared by both psychological stressors and psychotropic medications. Choosing the correct mood stabiliser without triggering angioedema was a major challenge in her treatment. Also, psychosocial interventions and frequent liaison with her immunology team were necessary to provide her with optimum care in the community. Here, we discuss the challenges we faced and how we overcame them in managing this rare presentation of coexisting BPAD and HAE. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2024. No commercial re-use. See rights and permissions. Published by BMJ.) |
| فهرسة مساهمة: | Keywords: Bipolar I disorder; Drug interactions; Immunology; Psychiatry (drugs and medicines); Unwanted effects / adverse reactions |
| تواريخ الأحداث: | Date Created: 20240917 Date Completed: 20240917 Latest Revision: 20240917 |
| رمز التحديث: | 20240918 |
| DOI: | 10.1136/bcr-2024-260597 |
| PMID: | 39289031 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1757-790X |
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| DOI: | 10.1136/bcr-2024-260597 |