التفاصيل البيبلوغرافية
| العنوان: |
Rapid determination of 54 dye components in hair dyes by liquid chromatography coupled to quadrupole orbitrap high-resolution mass spectrometry. |
| المؤلفون: |
Sun J; Jiangsu Institute for Food and Drug Control, Nanjing 210019, China., Xue GX; Jiangsu Institute for Food and Drug Control, Nanjing 210019, China.; Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China., Gong X; Jiangsu Institute for Food and Drug Control, Nanjing 210019, China., Zhang ZP; Jiangsu Institute for Food and Drug Control, Nanjing 210019, China., Xu J; Jiangsu Institute for Food and Drug Control, Nanjing 210019, China., Chen L; Jiangsu Institute for Food and Drug Control, Nanjing 210019, China., Cao L; Center for Inspection, Jiangsu Medical Products Administration, Nanjing 210019, China., Feng YL; Jiangsu Institute for Food and Drug Control, Nanjing 210019, China., Zhang YJ; School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China. zhangyj@ahtcm.edu.cn. |
| المصدر: |
Analytical methods : advancing methods and applications [Anal Methods] 2024 Sep 27. Date of Electronic Publication: 2024 Sep 27. |
| Publication Model: |
Ahead of Print |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: RSC Pub Country of Publication: England NLM ID: 101519733 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-9679 (Electronic) Linking ISSN: 17599660 NLM ISO Abbreviation: Anal Methods Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Cambridge : RSC Pub., 2009- |
| مستخلص: |
Chemical hair dye components can have allergenic, reproductive, and carcinogenic risks. Detecting restricted and prohibited ingredients in these products is challenging due to product diversity, isomer separation, instability, and wide polarity range. A method was developed using HPLC-high-resolution mass spectrometry for the qualitative and quantitative analysis of 54 hair dye components in various products. Samples were extracted with a 70% methanol solution, ultrasonicated in an ice bath, centrifuged, filtered, diluted with 25% methanol solution and 25% methanol solution containing 0.05% D-isoascorbic acid. Separation was achieved using an ACE Excel 3 C18 column (2.1 mm × 150 mm, 3 μm) with analysis conducted via quadrupole Orbitrap mass spectrometry. It showed good linear correlations, with detection limits of 0.1-23.5 ng mL -1 , and quantitation limits of 0.2-78.1 ng mL -1 . Average recovery ranged from 60.0% to 118.4%, with repeatability from 4.0% to 14.9%. Stability was confirmed within 48 hours. When applied to 20 batches of commercially available hair dyes, 24 hair dye components were found within permissible levels. The method is crucial for quality control of hair dyes, covering 10 common prohibited and 44 permissible hair dye components outlined in the Safety and Technical Standards for Cosmetics (2015 Edition). Compared to the standard methods, it can separate isomers in a single mobile phase system within 15 minutes in positive ion mode while maintaining sensitivity for phenol, hydroquinone, and other components in negative ion mode. Moreover, the pre-treatment strategy significantly improved stability and accuracy, enabling precise analysis of the 54 hair dye components. |
| تواريخ الأحداث: |
Date Created: 20240927 Latest Revision: 20240927 |
| رمز التحديث: |
20240927 |
| DOI: |
10.1039/d4ay00981a |
| PMID: |
39329180 |
| قاعدة البيانات: |
MEDLINE |
