دورية أكاديمية
Oral labetalol in the urgent treatment of severe hypertension.
العنوان: | Oral labetalol in the urgent treatment of severe hypertension. |
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المؤلفون: | Olowoyeye JO, Okoro EO, Omotosho AB |
المصدر: | Tropical and geographical medicine [Trop Geogr Med] 1986 Mar; Vol. 38 (1), pp. 73-8. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Foundation Tropical and Geographical Medicin Country of Publication: Netherlands NLM ID: 0376231 Publication Model: Print Cited Medium: Print ISSN: 0041-3232 (Print) Linking ISSN: 00413232 NLM ISO Abbreviation: Trop Geogr Med Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Hague : Foundation Tropical and Geographical Medicin Original Publication: Amsterdam [etc.] Foundation Tropical and Geographical Medicine [etc.] |
مواضيع طبية MeSH: | Hypertension/*drug therapy , Labetalol/*therapeutic use, Administration, Oral ; Adult ; Aged ; Female ; Heart Rate/drug effects ; Humans ; Labetalol/administration & dosage ; Male ; Middle Aged |
مستخلص: | 15 hypertensive patients presenting with diastolic blood pressures (DBP) of 130 mmHg or higher were hospitalised and treated with oral labetolol. They all received a diuretic and 400 mg of labetolol orally initially and subsequent doses at 2, 6, 12, 18 and 24 hours depending on the level of diastolic pressure. The mean of systolic/diastolic blood pressure dropped from 241/130 mmHg to 191/125 mmHg 30 minutes after the initial dose, and to 157/103 mmHg after six hours. Of the patients 73% had DBP of 115 mmHg or less six hours after the initial dose. Oral labetolol is recommended in hypertensive emergencies when sodium nitroprusside, diazoxide or trimethaphan cannot be used as an alternative to other agents. |
المشرفين على المادة: | R5H8897N95 (Labetalol) |
تواريخ الأحداث: | Date Created: 19860301 Date Completed: 19860516 Latest Revision: 20131121 |
رمز التحديث: | 20240627 |
PMID: | 3961913 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0041-3232 |
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