دورية أكاديمية

Pretreatment lymphangiography and operative evaluation in carcinoma of the cervix.

التفاصيل البيبلوغرافية
العنوان: Pretreatment lymphangiography and operative evaluation in carcinoma of the cervix.
المؤلفون: Lagasse LD, Ballon SC, Berman ML, Watring WG
المصدر: American journal of obstetrics and gynecology [Am J Obstet Gynecol] 1979 May 15; Vol. 134 (2), pp. 219-24.
نوع المنشور: Comparative Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0370476 Publication Model: Print Cited Medium: Print ISSN: 0002-9378 (Print) Linking ISSN: 00029378 NLM ISO Abbreviation: Am J Obstet Gynecol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2005->: New York : Elsevier
Original Publication: St. Louis.
مواضيع طبية MeSH: Lymph Node Excision* , Lymphography*, Uterine Cervical Neoplasms/*radiotherapy, Evaluation Studies as Topic ; Female ; Humans ; Lymphatic Metastasis ; Methods ; Neoplasm Staging ; Time Factors ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/surgery
مستخلص: Ninety-five patients with cervical carcinoma who were not candidates for definitive operation underwent initial lymphatic and 24-hour nodal phase lymphangiography and lymphadenectomy prior to radiation therapy. Operation by a transperitoneal or extraperitoneal approach consisted of bilateral pelvic and periaortic lymphadenectomy, exploratory laparotomy, and intraperitoneal biopsies as indicated by the findings. Radiation therapy was modified to include proved sites of metastases. Intestinal injuries followed transperitoneal operation and radiation therapy but were uncommon in patients in whom exploration was done by the extraperitoneal route. Eighteen patients (19%) had unsuspected metastases to common iliac or periaortic lymph nodes identified at operation. The characteristics of the primary tumor and the interpretation of the lymphangiogram provided an inaccurate basis on which to modify treatment. As further studies confirm the risk of disseminated disease in those patients with metastases to common iliac and the periaortic lymph nodes, future treatment plans might incorporate adjuvant chemotherapy or immunotherapy in addition to extended-field irradiation.
تواريخ الأحداث: Date Created: 19790515 Date Completed: 19790829 Latest Revision: 20190615
رمز التحديث: 20231215
DOI: 10.1016/0002-9378(79)90889-5
PMID: 453251
قاعدة البيانات: MEDLINE
الوصف
تدمد:0002-9378
DOI:10.1016/0002-9378(79)90889-5